Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Fredi Brühlmann"'
Autor:
V.S. Fatykhova, Fredi Brühlmann, Lucia S. Mukhtarova, Svetlana S. Gorina, Yana Y. Toporkova, Elena K. Bessolitsyna, Tatiana Ilyina, Alexander N. Grechkin, Elena O. Smirnova
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1863:369-378
The CYP74C subfamily of fatty acid hydroperoxide transforming enzymes includes hydroperoxide lyases (HPLs) and allene oxide synthases (AOSs). This work reports a new facet of the putative CYP74C HPLs. Initially, we found that the recombinant CYP74C13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a4659b1c35a54ddf1d1cf6953385a3
https://doi.org/10.1016/j.bbalip.2018.01.002
https://doi.org/10.1016/j.bbalip.2018.01.002
Autor:
Bojan Bosijokovic, Fredi Brühlmann
Publikováno v:
Organic Process Research & Development. 20:1974-1978
The biotechnological production of six-carbon membered green leaf aldehydes and alcohols appreciated for their fruity, green-grassy odors in fragrances and flavors exploits the 13-lipoxygenase pathway found in higher plants. Homogenized seeds, fruits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2777eb6dccc88e5f527f1bcca38f5ae
https://doi.org/10.1021/acs.oprd.6b00303
https://doi.org/10.1021/acs.oprd.6b00303
Autor:
Lucia S. Mukhtarova, Fredi Brühlmann, Bulat I. Khairutdinov, Alexander N. Grechkin, Mats Hamberg
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1863(10)
Hydroperoxide lyases (HPLs) of the CYP74 family (P450 superfamily) are widely distributed enzymes in higher plants and are responsible for the stress-initiated accumulation of short-chain aldehydes. Fatty acid hydroperoxides serve as substrates for H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025cbe022dd954f353169e883f8507af
https://pubmed.ncbi.nlm.nih.gov/30305246
https://pubmed.ncbi.nlm.nih.gov/30305246
Autor:
Nicolas Jeckelmann, Christophe Ullmann, Olivier P. Haefliger, Laurent Fourage, Cédric Dubois, Denis Wahler, Fredi Brühlmann
Publikováno v:
Journal of Biotechnology. 184:17-26
Directed evolution via iterative cycles of random and targeted mutagenesis was applied to the P450 domain of the subterminal fatty acid hydroxylase CYP102A1 of Bacillus megaterium to shift its regioselectivity towards the terminal position of palmiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302498d38fa14f45036d5eef3cbb01c3
https://doi.org/10.1016/j.jbiotec.2014.05.002
https://doi.org/10.1016/j.jbiotec.2014.05.002
Autor:
Christophe Ullmann, Pascal Auffray, Denis Wahler, Laurent Fourage, Bojan Bosijokovic, Fredi Brühlmann
Publikováno v:
Journal of Biotechnology. 163:339-345
The performance of a 13-hydroperoxide lyase from guava, an enzyme of the CYP74 family, which is of interest for the industrial production of saturated and unsaturated C6-aldehydes and their derivatives, was improved by directed evolution. Four rounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437581755b4795ed2779d50410390064
https://doi.org/10.1016/j.jbiotec.2012.11.005
https://doi.org/10.1016/j.jbiotec.2012.11.005
Publikováno v:
Biotechnology in Personal Care ISBN: 9780429113888
This chapter provides a summary of the main areas in which biotechnology hashad, and will in the future have, an impact on the fragrance industry.The implications of knowledge gained from biotechnology are clear to theperfume industry and provide muc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5501bfcbca68c5e53cdf3f957d6a020b
https://doi.org/10.3109/9781420015034-17
https://doi.org/10.3109/9781420015034-17
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1761:1419-1428
The conversion of linoleic acid 9-hydroperoxide (9-HPOD) by recombinant melon (Cucumis melo L.) hydroperoxide lyase (HPL, CYP74C subfamily) was studied. Short (5 s-1 min) incubations at 0 degrees C followed by rapid extraction and trimethylsilylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346765089c64fcfd1eed267837add8b1
https://doi.org/10.1016/j.bbalip.2006.09.002
https://doi.org/10.1016/j.bbalip.2006.09.002
Publikováno v:
Journal of Agricultural and Food Chemistry. 51:1410-1414
Formation of the flavor compound and precursor 4-hydroxy-5-methyl-3[2H]-furanone (HMF, norfuraneol) was demonstrated in cytosolic protein extracts obtained from Zygosaccharomyces rouxii after incubation with a number of carbohydrate phosphates. 4-Hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c4e83ce41225cc5846976a484a1762
https://doi.org/10.1021/jf025948m
https://doi.org/10.1021/jf025948m
Autor:
Fredi Brühlmann, Wilfred Chen
Publikováno v:
Biotechnology and Bioengineering. 63:544-551
Highly substituted polychlorinated biphenyls (PCBs) are known to be very resistant to aerobic biodegradation, particularly the initial attack by biphenyl dioxygenase. Functional evolution of the substrate specificity of biphenyl dioxygenase was demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79fb26a22c905feb432738832092eb51
https://doi.org/10.1002/(sici)1097-0290(19990605)63:5<544::aid-bit4>3.0.co
https://doi.org/10.1002/(sici)1097-0290(19990605)63:5<544::aid-bit4>3.0.co
Autor:
Noel T. Keen, Fredi Brühlmann
Publikováno v:
Gene. 202:45-51
The pel gene from an Amycolata sp. encoding a pectate lyase (EC 4.2.2.2) was isolated by activity screening a genomic DNA library in Streptomyces lividans TK24. Subsequent subcloning and sequencing of a 2.3 kb Bam HI– Bgl II fragment revealed an op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e5d4dd8333427c4393d3fa73d3ff72
https://doi.org/10.1016/s0378-1119(97)00449-6
https://doi.org/10.1016/s0378-1119(97)00449-6