The angiotensin AT2-receptor agonist compound 21 is an antagonist for the thromboxane TP-receptor – Implications for preclinical studies and future clinical use

Autor: Fredgart, Maise H. ^{a, 1}, Leurgans, Thomas M. ^{a, 1}, Stenelo, Martin ^a, Nybo, Mads ^b, Bloksgaard, Maria ^a, Lindblad, Lena ^c, De Mey, Jo G.R. ^{a, 1}, Steckelings, U. Muscha ^{a, ⁎, 1}

Publikováno v: In Peptides June 2023 164

Endothelin‐1 shifts the mediator of bradykinin‐induced relaxation from NO to H2O2 in resistance arteries from patients with cardiovascular disease

Autor: Leurgans, Thomas M, Bloksgaard, Maria, Brewer, Jonathan R, Bagatolli, Luis A, Fredgart, Maise H, Rosenstand, Kristoffer, Hansen, Maria L, Rasmussen, Lars M, Irmukhamedov, Akhmadjon, De Mey, Jo G R

Publikováno v: Leurgans, T M, Bloksgaard, M, Brewer, J R, Bagatolli, L A, Fredgart, M H, Rosenstand, K, Hansen, M L, Rasmussen, L M, Irmukhamedov, A & De Mey, J G R 2016, ' Endothelin-1 shifts the mediator of bradykinin-induced relaxation from NO to H2 O2 in resistance arteries from patients with cardiovascular disease ', British Journal of Pharmacology, vol. 173, no. 10, pp. 1653-1664 . https://doi.org/10.1111/bph.13467

Background and Purpose We tested the hypothesis that in resistance arteries from cardiovascular disease (CVD) patients, effects of an endothelium-dependent vasodilator depend on the contractile stimulus. Experimental Approach Arteries dissected from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b5612a66fc426f1bd9990d11f509aee8
https://europepmc.org/articles/PMC4842913/