On the current failure -- but bright future -- of topology-driven biological network alignment

Autor: Wang, Siyue, Chen, Xiaoyin, Frederisy, Brent J., Mbakogu, Benedict A., Kanne, Amy D., Khosravi, Pasha, Hayes, Wayne B.

Publikováno v: "On the current failure--but bright future--of topology-driven biological network alignment". Advances in Protein Chemistry and Structural Biology, Volume 131 (2022), pp. 1-44

The function of a protein is defined by its interaction partners. Thus, topology-driven network alignment of the protein-protein interaction (PPI) networks of two species should uncover similar interaction patterns and allow identification of functio

Externí odkaz: http://arxiv.org/abs/2204.11999