Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Frederike Wilkens"'
Autor:
Rielana Wichert, Anna Ermund, Stefanie Schmidt, Matthias Schweinlin, Miroslaw Ksiazek, Philipp Arnold, Katharina Knittler, Frederike Wilkens, Barbara Potempa, Björn Rabe, Marit Stirnberg, Ralph Lucius, Jörg W. Bartsch, Susanna Nikolaus, Maren Falk-Paulsen, Philip Rosenstiel, Marco Metzger, Stefan Rose-John, Jan Potempa, Gunnar C. Hansson, Peter J. Dempsey, Christoph Becker-Pauly
Publikováno v:
Cell Reports, Vol 21, Iss 8, Pp 2090-2103 (2017)
The host metalloprotease meprin β is required for mucin 2 (MUC2) cleavage, which drives intestinal mucus detachment and prevents bacterial overgrowth. To gain access to the cleavage site in MUC2, meprin β must be proteolytically shed from epithelia
Externí odkaz:
https://doaj.org/article/b24e999113e241ad82f86e3fbecdd8d3
Autor:
Jan Potempa, Frederike Wilkens, Christoph Becker-Pauly, Jörg W. Bartsch, Philipp Arnold, Miroslaw Ksiazek, Susanna Nikolaus, Stefan Rose-John, Barbara Potempa, Marit Stirnberg, Anna Ermund, Peter J. Dempsey, Rielana Wichert, Matthias Schweinlin, Marco Metzger, Philip Rosenstiel, Björn Rabe, Gunnar C. Hansson, Ralph Lucius, Maren Falk-Paulsen, Katharina Knittler, Stefanie Schmidt
Publikováno v:
CELL Reports
Cell Reports, Vol 21, Iss 8, Pp 2090-2103 (2017)
Cell Reports, Vol 21, Iss 8, Pp 2090-2103 (2017)
Summary The host metalloprotease meprin β is required for mucin 2 (MUC2) cleavage, which drives intestinal mucus detachment and prevents bacterial overgrowth. To gain access to the cleavage site in MUC2, meprin β must be proteolytically shed from e