Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Frederike Tebbe"'
Autor:
Benedikt Goretzki, Christoph Wiedemann, Brett A. McCray, Stefan L. Schäfer, Jasmin Jansen, Frederike Tebbe, Sarah-Ana Mitrovic, Julia Nöth, Ainara Claveras Cabezudo, Jack K. Donohue, Cy M. Jeffries, Wieland Steinchen, Florian Stengel, Charlotte J. Sumner, Gerhard Hummer, Ute A. Hellmich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Intrinsically disordered regions (IDRs) are essential for membrane receptor regulation but often remain unresolved in structural studies. TRPV4, a member of the TRP vanilloid channel family involved in thermo- and osmosensation, has a large
Externí odkaz:
https://doaj.org/article/164d0c141a984b619e153ae313a859dd
Autor:
Christoph Wiedemann, Benedikt Goretzki, Zoe N. Merz, Frederike Tebbe, Pauline Schmitt, Ute A. Hellmich
Publikováno v:
Biomolecular NMR Assignments. 16:289-296
The mammalian Transient Receptor Potential Vanilloid (TRPV) channels are a family of six tetrameric ion channels localized at the plasma membrane. The group I members of the family, TRPV1 through TRPV4, are heat-activated and exhibit remarkable polym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883161995a24e3eebc9073bde0f5c4c8
https://doi.org/10.1007/s12104-022-10093-4
https://doi.org/10.1007/s12104-022-10093-4
Autor:
Robin Deutscher, Safa Karagöz, Patrick Purder, Jürgen Kolos, Christian Meyners, Wisely Sugiarto, Patryk Krajczy, Frederike Tebbe, Thomas Geiger, Can Ünal, Ute Hellmich, Michael Steinert, Felix Hausch
Legionella pneumophila is the causative agent of Legionnaires’ disease, a serious form of pneumonia. Its macrophage infectiv-ity potentiator (Mip), a member of a highly conserved family of FK506-binding proteins, plays a major role in the prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b1e3a142490dbd2b62838f42f6324e9
https://doi.org/10.26434/chemrxiv-2023-vfssm
https://doi.org/10.26434/chemrxiv-2023-vfssm
Autor:
Benedikt Goretzki, Christoph Wiedemann, Brett A. McCray, Stefan L. Schäfer, Jasmin Jansen, Frederike Tebbe, Sarah-Ana Mitrovic, Julia Nöth, Jack K. Donohue, Cy M. Jeffries, Wieland Steinchen, Florian Stengel, Charlotte J. Sumner, Gerhard Hummer, Ute A. Hellmich
Intrinsically disordered regions (IDRs) are essential for membrane receptor regulation but often remain unresolved in structural studies. TRPV4, a member of the TRP vanilloid channel family involved in thermo- and osmosensation, has a large N-termina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f44518da6b4f14f311d51b48232e18bc
https://doi.org/10.1101/2022.12.21.521430
https://doi.org/10.1101/2022.12.21.521430
Publikováno v:
Biomolecular NMR assignments. 16(2)
Transient receptor potential (TRP) channels are important pharmacological targets due to their ability to act as sensory transducers on the organismic and cellular level, as polymodal signal integrators and because of their role in numerous diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db60dc96ddb32b3b04587fb528bb441
https://pubmed.ncbi.nlm.nih.gov/35451798
https://pubmed.ncbi.nlm.nih.gov/35451798
Publikováno v:
Journal of Molecular Biology. 433:166931
The first genuine high-resolution single particle cryo-electron microscopy structure of a membrane protein determined was a transient receptor potential (TRP) ion channel, TRPV1, in 2013. This methodical breakthrough opened up a whole new world for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d1a7367c9ba0f9970c72388796bcc3
https://doi.org/10.1016/j.jmb.2021.166931
https://doi.org/10.1016/j.jmb.2021.166931