Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Frederike Lentz"'
Autor:
Tim Friede, Martin Posch, Sarah Zohar, Corinne Alberti, Norbert Benda, Emmanuelle Comets, Simon Day, Alex Dmitrienko, Alexandra Graf, Burak Kürsad Günhan, Siew Wan Hee, Frederike Lentz, Jason Madan, Frank Miller, Thomas Ondra, Michael Pearce, Christian Röver, Artemis Toumazi, Steffen Unkel, Moreno Ursino, Gernot Wassmer, Nigel Stallard
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-9 (2018)
Abstract Where there are a limited number of patients, such as in a rare disease, clinical trials in these small populations present several challenges, including statistical issues. This led to an EU FP7 call for proposals in 2013. One of the three
Externí odkaz:
https://doaj.org/article/9b388cef7daa4326aa630be227e4381e
Autor:
Emmanuelle Comets, Corinne Alberti, Tim Friede, Artemis Toumazi, Moreno Ursino, Frederike Lentz, Nigel Stallard, Sarah Zohar
Publikováno v:
Computer Methods and Programs in Biomedicine
Computer Methods and Programs in Biomedicine, Elsevier, 2018, 157, pp.163-177. ⟨10.1016/j.cmpb.2018.01.023⟩
Computer Methods and Programs in Biomedicine, 2018, 157, pp.163-177. ⟨10.1016/j.cmpb.2018.01.023⟩
Computer Methods and Programs in Biomedicine, Elsevier, 2018, 157, pp.163-177. ⟨10.1016/j.cmpb.2018.01.023⟩
Computer Methods and Programs in Biomedicine, 2018, 157, pp.163-177. ⟨10.1016/j.cmpb.2018.01.023⟩
International audience; Background and objective - Dose-finding, aiming at finding the maximum tolerated dose, and pharmacokinetics studies are the first in human studies in the development process of a new pharmacological treatment. In the literatur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348731ed931352b7bf52edab9afdd63f
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01737106/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01737106/document
Autor:
Emmanuelle Comets, Martin Posch, Simon Day, A. Tournazi, Christian Röver, A. Dmitrenko, Burak Kürsad Günhan, Norbert Benda, Jason Madan, Corinne Alberti, Steffen Unkel, Nigel Stallard, Michael Pearce, Sarah Zohar, Frank Miller, Moreno Ursino, Frederike Lentz, Thomas Ondra, Tim Friede, Alexandra Graf, Gernot Wassmer, Siew Wan Hee
Publikováno v:
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, 2018, 13 (1), pp.186. ⟨10.1186/s13023-018-0919-y⟩
Orphanet Journal of Rare Diseases, BioMed Central, 2018, 13 (1), pp.186. ⟨10.1186/s13023-018-0919-y⟩
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-9 (2018)
Orphanet Journal of Rare Diseases, 2018, 13 (1), pp.186. ⟨10.1186/s13023-018-0919-y⟩
Orphanet Journal of Rare Diseases, BioMed Central, 2018, 13 (1), pp.186. ⟨10.1186/s13023-018-0919-y⟩
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-9 (2018)
Where there are a limited number of patients, such as in a rare disease, clinical trials in these small populations present several challenges, including statistical issues. This led to an EU FP7 call for proposals in 2013. One of the three projects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b74312613901ebe4824e310be45041
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01935072/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01935072/document
Autor:
Flora Musuamba Tshinanu, Frederike Lentz, Wei Zhao, Anna Karin Hamberg, Norbert Benda, Joseph F. Standing, Cecile Ollivier, Andrew Thomson, Sofia Friberg Hietala, Efthymios Manolis, Gérard Pons, Susan Cole, Paolo Tomasi, Ine Skottheim Rusten, María J. Garrido, Valeria Gigante, Ralf Herold, Anna Nordmark, Johannes Taminiau
Publikováno v:
Fundamentals of Pediatric Drug Dosing ISBN: 9783319437521
For a paediatric development to be rationally informed by all available knowledge, it is necessary to systematically collect and learn from available data, expert knowledge and prior developments. Aspects such as drug formulation, bioanalytical metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5211cde2b733f8349acdf1c43ee24f18
https://doi.org/10.1007/978-3-319-43754-5_7
https://doi.org/10.1007/978-3-319-43754-5_7
Autor:
Essam Kerwash, Frederike Lentz, Aris Dokoumetzidis, Joseph F. Standing, Flora T. Musuamba, Francesca Serone, Jacob Brogren, Susan Cole, Gaby Wangorsch, Anna Nordmark, Wei Zhao, Victor Mangas Sanjuan, Michiel van den Heuvel, David Khan, Gérard Pons, Johannes Taminiau, Norbert Benda, Justin L. Hay, Ine Skottheim Rusten, Kristin E. Karlsson, Valeria Gigante, Juha Vakkilainen, Efthymios Manolis
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 6:416-417
During the last 10 years the European Medicines Agency (EMA) organized a number of workshops on modeling and simulation, working towards greater integration of modeling and simulation (M&S) in the development and regulatory assessment of medicines. I
Autor:
Bernhard K. Keppler, Magdalena Henke, Andreas Lindauer, Max E. Scheulen, Christian G. Hartinger, Ralf A. Hilger, Christian Dittrich, Ulrich Jaehde, Frederike Lentz, A. Drescher
Publikováno v:
Anti-Cancer Drugs. 20:97-103
A phase I and pharmacokinetic study was carried out with the new ruthenium complex indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019, FFC14A). Seven patients with various types of solid tumours refractory to standard therapy were t
Publikováno v:
American journal of pharmacogenomics : genomics-related research in drug development and clinical practice. 5(1)
Hepatic metastases occur in about half of patients with colorectal cancer. Since hepatic metastases are often not accessible for surgery, chemotherapy of metastases is important. The most commonly used chemotherapy drugs for hepatic metastases are fl
Autor:
Hilgers, Ralf-Dieter, Roes, Kit, Stallard, Nigel, IDeAl, Asterix, Alberti, Corinne, Van Baal, Caroline, Benda, Norbert, Biesheuvel, Egbert, Burmann, CarlFredrik, Bogdan, Malgorzata, Comets, Emmanuelle, Day, Simon, Dette, Holger, Dmitrienko, Alex, Friede, Tim, Graf, Alexandra, Karlsson, Mats, Koch, Armin, König, Franz, Van Der Lee, JohannaH., Lentz, Frederike, Madan, Jason, Male, Christoph, Mentré, France, Miller, Frank, Molenberghs, Geert, Neuenschwander, Beat, Posch, Martin, Oosterwijk, Cor, Röver, Christian, Senn, Stephen, Torres, Ferran, Zohar, Sarah
Publikováno v:
Orphanet journal of rare diseases, 11:78
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, BioMed Central, 2016, 11 (1), ⟨10.1186/s13023-016-0464-5⟩
Orphanet journal of rare diseases 11(1), 78 (2016). doi:10.1186/s13023-016-0464-5
Orphanet Journal of Rare Diseases, 2016, 11 (1), ⟨10.1186/s13023-016-0464-5⟩
Orphanet Journal of Rare Diseases, 11(1). BioMed Central
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, BioMed Central, 2016, 11 (1), ⟨10.1186/s13023-016-0464-5⟩
Orphanet journal of rare diseases 11(1), 78 (2016). doi:10.1186/s13023-016-0464-5
Orphanet Journal of Rare Diseases, 2016, 11 (1), ⟨10.1186/s13023-016-0464-5⟩
Orphanet Journal of Rare Diseases, 11(1). BioMed Central
Orphanet journal of rare diseases : OJRD 11(1), 78 (2016). doi:10.1186/s13023-016-0464-5
Published by BioMed Central, London
Published by BioMed Central, London
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1594ff132306df0afd229c81c5aeed
https://repository.publisso.de/resource/frl:6407631
https://repository.publisso.de/resource/frl:6407631