Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Frederike Boos"'
Autor:
Matthias S. Leisegang, Jasleen Kaur Bains, Sandra Seredinski, James A. Oo, Nina M. Krause, Chao-Chung Kuo, Stefan Günther, Nevcin Sentürk Cetin, Timothy Warwick, Can Cao, Frederike Boos, Judit Izquierdo Ponce, Shaza Haydar, Rebecca Bednarz, Chanil Valasarajan, Dominik C. Fuhrmann, Jens Preussner, Mario Looso, Soni S. Pullamsetti, Marcel H. Schulz, Hendrik R. A. Jonker, Christian Richter, Flávia Rezende, Ralf Gilsbach, Beatrice Pflüger-Müller, Ilka Wittig, Ingrid Grummt, Teodora Ribarska, Ivan G. Costa, Harald Schwalbe, Ralf P. Brandes
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Using a composite bioinformatics approach, the DNA:DNA:RNA triplex-forming lncRNAs HIF1α-AS1 was identified in human endothelial cells which recruits an epigenetic silencing complex to limit expression of triplex target genes.
Externí odkaz:
https://doaj.org/article/c3f7ecd225714cd98fa4bafc76a4baa2
Autor:
Sandra Seredinski, Frederike Boos, Stefan Günther, James A. Oo, Timothy Warwick, Judit Izquierdo Ponce, Felix F. Lillich, Ewgenij Proschak, Stefan Knapp, Ralf Gilsbach, Beatrice Pflüger-Müller, Ralf P. Brandes, Matthias S. Leisegang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 1023-1035 (2022)
The transcription factor hypoxia-inducible factor 1 (HIF1) is an important driver of cancer and is therefore an attractive drug target. Acriflavine (ACF) has been suggested to inhibit HIF1, but its mechanism of action is unknown. Here we investigated
Externí odkaz:
https://doaj.org/article/d2c040d46b964198bf7fd06e20946563
Autor:
Frederike Boos, James A. Oo, Timothy Warwick, Stefan Günther, Judit Izquierdo Ponce, Melina Lopez, Diba Rafii, Giulia Buchmann, Minh Duc Pham, Zahraa S. Msheik, Tianfu Li, Sandra Seredinski, Shaza Haydar, Sepide Kashefiolasl, Karl H. Plate, Rüdiger Behr, Matthias Mietsch, Jaya Krishnan, Soni S. Pullamsetti, Sofia-Iris Bibli, Rabea Hinkel, Andrew H. Baker, Reinier A. Boon, Marcel H. Schulz, Ilka Wittig, Francis J. Miller, Ralf P. Brandes, Matthias S. Leisegang
Publikováno v:
Basic Research in Cardiology, 118(1):5. Springer
Boos, F, Oo, J A, Warwick, T, Günther, S, Izquierdo Ponce, J, Lopez, M, Rafii, D, Buchmann, G, Pham, M D, Msheik, Z S, Li, T, Seredinski, S, Haydar, S, Kashefiolasl, S, Plate, K H, Behr, R, Mietsch, M, Krishnan, J, Pullamsetti, S S, Bibli, S, Hinkel, R, Baker, A H, Boon, R A, Schulz, M H, Wittig, I, Miller, F J, Brandes, R P & Leisegang, M S 2023, ' The endothelial-enriched lncRNA LINC00607 mediates angiogenic function ', Basic research in cardiology, vol. 118, no. 1, 5 . https://doi.org/10.1007/s00395-023-00978-3
Boos, F, Oo, J A, Warwick, T, G?nther, S, Izquierdo Ponce, J, Lopez, M, Rafii, D, Buchmann, G, Pham, M D, Msheik, Z S, Li, T, Seredinski, S, Haydar, S, Kashefiolasl, S, Plate, K H, Behr, R D, Mietsch, M, Krishnan, J, Pullamsetti, S S, Bibli, S-I, Hinkel, R, Baker, A H, Boon, R A, Schulz, M H, Wittig, I, Miller, F J, Brandes, R P & Leisegang, M S 2023, ' The endothelial-enriched lncRNA LINC00607 mediates angiogenic function ', Basic Research in Cardiology, vol. 118, no. 1, 5 . https://doi.org/10.1007/s00395-023-00978-3
Basic Research in Cardiology, 118(1):5. D. Steinkopff-Verlag
Boos, F, Oo, J A, Warwick, T, Günther, S, Izquierdo Ponce, J, Lopez, M, Rafii, D, Buchmann, G, Pham, M D, Msheik, Z S, Li, T, Seredinski, S, Haydar, S, Kashefiolasl, S, Plate, K H, Behr, R, Mietsch, M, Krishnan, J, Pullamsetti, S S, Bibli, S, Hinkel, R, Baker, A H, Boon, R A, Schulz, M H, Wittig, I, Miller, F J, Brandes, R P & Leisegang, M S 2023, ' The endothelial-enriched lncRNA LINC00607 mediates angiogenic function ', Basic research in cardiology, vol. 118, no. 1, 5 . https://doi.org/10.1007/s00395-023-00978-3
Boos, F, Oo, J A, Warwick, T, G?nther, S, Izquierdo Ponce, J, Lopez, M, Rafii, D, Buchmann, G, Pham, M D, Msheik, Z S, Li, T, Seredinski, S, Haydar, S, Kashefiolasl, S, Plate, K H, Behr, R D, Mietsch, M, Krishnan, J, Pullamsetti, S S, Bibli, S-I, Hinkel, R, Baker, A H, Boon, R A, Schulz, M H, Wittig, I, Miller, F J, Brandes, R P & Leisegang, M S 2023, ' The endothelial-enriched lncRNA LINC00607 mediates angiogenic function ', Basic Research in Cardiology, vol. 118, no. 1, 5 . https://doi.org/10.1007/s00395-023-00978-3
Basic Research in Cardiology, 118(1):5. D. Steinkopff-Verlag
Long non-coding RNAs (lncRNAs) can act as regulatory RNAs which, by altering the expression of target genes, impact on the cellular phenotype and cardiovascular disease development. Endothelial lncRNAs and their vascular functions are largely undefin
Autor:
James A. Oo, Katalin Pálfi, Timothy Warwick, Ilka Wittig, Cristian Prieto-Garcia, Vigor Matkovic, Ines Tomašković, Frederike Boos, Judit Izquierdo Ponce, Tom Teichmann, Kirill Petriukov, Shaza Haydar, Lars Maegdefessel, Zhiyuan Wu, Minh Duc Pham, Jaya Krishnan, Andrew H. Baker, Stefan Günther, Helle D. Ulrich, Ivan Dikic, Matthias S. Leisegang, Ralf P. Brandes
Publikováno v:
Cell Reports, 41(7):111670. Cell Press
Cell Reports: Methods
Cell Reports: Methods
In healthy vessels, endothelial cells maintain a stable, differentiated, and growth-arrested phenotype for years. Upon injury, a rapid phenotypic switch facilitates proliferation to restore tissue perfusion. Here we report the identification of the e
Autor:
James A Oo, Katalin Pálfi, Timothy Warwick, Ilka Wittig, Frederike Boos, Matthias Leisegang, Ralf P Brandes
Publikováno v:
Circulation Research. 131
Background: Long noncoding RNAs (lncRNA) provide an additional layer of molecular control in pathways crucial for vascular development and cardiovascular disease. We set out to identify novel endothelial lncRNAs that could be exploited to treat vascu
Autor:
Frederike Boos, James A. Oo, Timothy Warwick, Stefan Günther, Judit Izquierdo Ponce, Giulia Buchmann, Tianfu Li, Sandra Seredinski, Shaza Haydar, Sepide Kashefiolasl, Andrew H. Baker, Reinier A. Boon, Marcel H. Schulz, Francis J. Miller, Ralf P. Brandes, Matthias S. Leisegang
Long non-coding RNAs (lncRNAs) can act as regulatory RNAs which, by altering the expression of target genes, impact on the cellular phenotype and cardiovascular disease development. Endothelial lncRNAs and their vascular functions are largely undefin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91d85960d8dafbc1eed26169a3658845
https://doi.org/10.1101/2022.05.09.491127
https://doi.org/10.1101/2022.05.09.491127