Výsledky vyhledávání - "Frederik Lessmann"

A method for reliable quantification of mercury in occupational and environmental medical urine samples by inductively coupled plasma mass spectrometry

Autor: Martin Winter, Frederik Lessmann, Volker Harth

Publikováno v: Analytical Methods. 15:2030-2038

Using a specific mixture of HNO3, HCl and thiourea for sample preparation overcomes common challenges of mercury determination in urine samples by inductively coupled plasma mass spectrometry.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bd6a39f1fa1d91e44835a26dcc6f4c8
https://doi.org/10.1039/d2ay02051c

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Metal exposure of workers during recycling of electronic waste: a cross-sectional study in sheltered workshops in Germany

Autor: Frederik Lessmann, Volker Harth, Katrin Pitzke, Albert Nienhaus, Johannes Gerding, Johanna Stranzinger, Claudia Peters, Wolfgang Wegscheider, Udo Eickmann

Publikováno v: International Archives of Occupational and Environmental Health

Objectives In Germany, the initial step of electronic waste (e-waste) recycling frequently takes place in sheltered workshops for physically and mentally handicapped workers (Werkstätten für behinderte Menschen (WfbM), in german language). E-waste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3f328476b5b016a33e4ea0a946acbb
https://pubmed.ncbi.nlm.nih.gov/33486553

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Metabolism and urinary excretion kinetics of di(2-ethylhexyl) terephthalate (DEHTP) in three male volunteers after oral dosage

Autor: Tobias Weiss, Thomas Brüning, André Schütze, Rainer Otter, Angelika Langsch, Frederik Lessmann, Holger M. Koch

Publikováno v: Archives of Toxicology. 90:1659-1667

Di(2-ethylhexyl) terephthalate (DEHTP) is used as a substitute for di(2-ethylhexyl) phthalate (DEHP), an ortho-phthalate-based plasticizer that is classified and labeled due to its toxicity to reproduction. In this study the metabolism and urinary ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd966744fac0a18f9c872d0c86157bc
https://doi.org/10.1007/s00204-016-1715-x

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Metabolites of the substitute plasticiser Di-(2-ethylhexyl) terephthalate (DEHTP) in urine of children and adolescents investigated in the German Environmental Survey GerES V, 2014–2017

Autor: André Conrad, Frederik Lessmann, Enrico Rucic, Gerda Schwedler, Marike Kolossa-Gehring, Thomas Brüning, Maria I.H. Schmied-Tobies, Holger M. Koch

Publikováno v: International Journal of Hygiene and Environmental Health. 230:113589

Metabolites of di-(2-ethylhexyl) terephthalate (DEHTP), a substitute for ortho-based phthalate plasticisers like di-(2-ethylhexyl) phthalate (DEHP), were analysed in 2112 first-morning void urine samples from children and adolescents aged 3–17 year

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fbb6513fa7b0616ac05e5a098a8979
https://doi.org/10.1016/j.ijheh.2020.113589

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HC-GC-MS Determination of the Inhalational Anesthetic Sevoflurane and its Specific Metabolite Hexafluoroisopropanol (HFIP) in Human Urine: Monitoring of Occupational Background Exposures

Autor: Volker Harth, Frederik Lessmann, Susann Finger

Publikováno v: ISEE Conference Abstracts. 2018

Today, sevoflurane is one of the most used inhalational anesthetics in human surgery, due to favourable pharmacological properties. However, teratogenic and neurotoxic effects resulting from chroni...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd5b57b34e5470c1afc8fe784cfbe4ee
https://doi.org/10.1289/isesisee.2018.p02.3290

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LC-HRMS Biomarker Suspect Screening in Low Dose Studies

Autor: Thomas Brüning, Frederik Lessmann, Holger M. Koch, Kathrin Papadopoulos, Heiko Hayen, Alexandra Nehring, Daniel Bury, Tobias Weiss

Publikováno v: ISEE Conference Abstracts. 2018

Exposure biomarker development is a time consuming procedure, starting with identification of presumably appropriate metabolites of the xenobiotic in question. Investing into unsuitable biomarker c...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c07cae2357d3dca86a1c7144282833d6
https://doi.org/10.1289/isesisee.2018.p03.3400

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De-novo identification of specific exposure biomarkers of the alternative plasticizer di(2-ethylhexyl) terephthalate (DEHTP) after low oral dosage to male volunteers by HPLC-Q-Orbitrap-MS

Autor: Tobias Weiss, Heiko Hayen, Frederik Lessmann, Thomas Brüning, Holger M. Koch, Daniel Bury

Publikováno v: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 23(2)

Human exposure biomonitoring relies on the availability of specific, sensitive biomarkers. For emerging chemicals, the identification (prediction, synthesis, verification) of such biomarkers is time and cost intensive.This study aimed to further eluc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c4c4f8e1989543847024eefdeedbea
https://pubmed.ncbi.nlm.nih.gov/29179593

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Exposure to the plasticizer di(2-ethylhexyl) terephthalate (DEHTP) in Portuguese children - Urinary metabolite levels and estimated daily intakes

Autor: Frederik Lessmann, Valentina F. Domingues, Tobias Weiss, Thomas Brüning, Holger M. Koch, Luísa Correia-Sá, Conceição Calhau

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Environment International, Vol 104, Iss, Pp 25-32 (2017)

Classical ortho-phthalate plasticizers are, due to their endocrine disrupting potency and reproductive toxicity, increasingly replaced by alternative plasticizers. Di(2-ethylhexyl) terephthalate (DEHTP) is one of these substitutes. In this study, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2108a6fd2a3fea40bc4f196f23981afc
https://pubmed.ncbi.nlm.nih.gov/28407489

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Analyzing terephthalate metabolites in human urine as biomarkers of exposure: Importance of selection of metabolites and deconjugation enzyme

Autor: Volker Harth, Ruthann A. Rudel, Anna-Maria Andersson, Jochen F. Mueller, Carl-Gustaf Bornehag, Amrit Kaur Sakhi, Cathrine Thomsen, Thomas Brüning, Russ Hauser, Holger M. Koch, Frederik Lessmann, Marike Kolossa-Gehring, Hanne Frederiksen, Joseph M. Braun, Shanna H. Swan

Publikováno v: Journal of Chromatography B. :91-92

Owing to their toxicity, phthalate plasticizers are currently being replaced with terephthalates in many consumer products. Nevertheless, data on human exposure to and toxicity of terephthalates are still scarce. In this study, we developed a robust

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ba08ab45e2036f0d2f0b1acc584f2e
https://doi.org/10.1016/j.jchromb.2018.09.035

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