Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Frederik J.S. Doerr"'
Publikováno v:
International Journal of Pharmaceutics: X, Vol 2, Iss , Pp 100041- (2020)
The application of X-ray microtomography for quantitative structural analysis of pharmaceutical multi-particulate systems was demonstrated for commercial capsules, each containing approximately 300 formulated ibuprofen pellets. The implementation of
Externí odkaz:
https://doaj.org/article/45ce2643acb14cd9a10a403f8946cca5
Autor:
Eleonora Paladino, Frederik J.S. Doerr, Ecaterina Bordos, Iyke I. Onyemelukwe, Dimitrios A. Lamprou, Alastair J. Florence, Ian S. Gilmore, Gavin W. Halbert
Publikováno v:
Paladino, E, Doerr, F J S, Bordos, E, Onyemelukwe, I I, Lamprou, D A, Florence, A J, Gilmore, I S & Halbert, G W 2022, ' High spatial resolution ToF-SIMS imaging and image analysis strategies to monitor and quantify early phase separation in amorphous solid dispersions ', International Journal of Pharmaceutics, vol. 628, 122191 . https://doi.org/10.1016/j.ijpharm.2022.122191
Amorphous solid dispersions (ASDs) are formulations with enhanced drug solubility and dissolution rate compared to their crystalline counterparts, however, they can be inherently thermodynamically unstable. This can lead to amorphous phase separation
Autor:
Rebecca L. Davis-Harrison, Alastair J. Florence, Jeremy Hinds, Scott Alan Frank, Frederik J.S. Doerr, Lee J. Burns, Becky Lee
Publikováno v:
Pharmaceutical Research
Purpose Spray drying plays an important role in the pharmaceutical industry for product development of sensitive bio-pharmaceutical formulations. Process design, implementation and optimisation require in-depth knowledge of process-product interactio
The implementation of a particle design platform that can be applied to novel pharmaceutical systems using acoustic levitation (SAL) and X-ray tomography (XRT) is discussed. Acoustic levitation was employed to provide a container-less particle design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e19334e8fa572b79961fdfcebadb4c
https://strathprints.strath.ac.uk/66187/1/Doerr_etal_APT_2018_Quantitative_investigation_of_particle_formation_of_a_model_pharmaceutical_formulation.pdf
https://strathprints.strath.ac.uk/66187/1/Doerr_etal_APT_2018_Quantitative_investigation_of_particle_formation_of_a_model_pharmaceutical_formulation.pdf
Publikováno v:
International Journal of Pharmaceutics. :118897