Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Frederik Götte"'
Autor:
Maurizio Mangolini, Frederik Götte, Andrew Moore, Tim Ammon, Madlen Oelsner, Gloria Lutzny-Geier, Ludger Klein-Hitpass, James C. Williamson, Paul J. Lehner, Jan Dürig, Michael Möllmann, Lívia Rásó-Barnett, Katherine Hughes, Antonella Santoro, Simón Méndez-Ferrer, Robert A. J. Oostendorp, Ursula Zimber-Strobl, Christian Peschel, Daniel J. Hodson, Marc Schmidt-Supprian, Ingo Ringshausen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The Wnt pathway is one of the core de-regulated pathways in chronic lymphocytic leukaemia (CLL) and is activated in only a subset of patients; however, no universal drivers of the disease have been identified. Here the authors show that Notch2 and β
Externí odkaz:
https://doaj.org/article/c4f9c099f3104cabbf026773512a17d1
Integration of innate into adaptive immune responses in ZAP-70–positive chronic lymphocytic leukemia
Autor:
George A. Follows, Madlen Oelsner, Andrew W. Moore, E. Joanna Baxter, Torsten Haferlach, Michael Fiegl, Michaela Wagner, Christian Bogner, Frederik Götte, Christian Peschel, Ingo Ringshausen, Peer-Hendrik Kuhn
Publikováno v:
Blood. 127:436-448
The crucial dependence of chronic lymphocytic leukemia (CLL) cells on signals derived from the B cell receptor (BCR) has encouraged the development of new inhibitors, which interfere with BCR signaling and demonstrate clinical benefits in nearly all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5818b883effd6094beb7a309d86dc123
https://doi.org/10.1182/blood-2015-05-646935
https://doi.org/10.1182/blood-2015-05-646935