Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Frederik E. Stuurman"'
Autor:
Guilherme S. Ferreira, Francis M. Dijkstra, Désirée H. Veening-Griffioen, Wouter P. C. Boon, Huub Schellekens, Ellen H. M. Moors, Peter J. K. van Meer, Frederik E. Stuurman, Joop M. A. van Gerven
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The primary purpose of this study was to assess the translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system (CNS) active drugs. As a part of this, IBs were reviewed on re
Externí odkaz:
https://doaj.org/article/969744b409794e0e8e65ec07d7ce391d
Autor:
Janine M. Knijff, Euphemia C.A.M. Houdijk, Daniëlle C.M. van der Kaay, Youri van Berkel, Luc Filippini, Frederik E. Stuurman, Adam F. Cohen, Gertjan J.A. Driessen, Matthijs D. Kruizinga
Publikováno v:
Digital Biomarkers, Vol 6, Iss 1, Pp 19-29 (2022)
Introduction: Clinical research and treatment of childhood obesity is challenging, and objective biomarkers obtained in a home-setting are needed. The aim of this study was to determine the potential of novel digital endpoints gathered by a home-moni
Externí odkaz:
https://doaj.org/article/d1452989deb8421099a4a5eb315707d9
Autor:
Amee Sonigra, Hendrik J. Nel, Pascale Wehr, Nishta Ramnoruth, Swati Patel, Karin A. van Schie, Maxwell W. Bladen, Ahmed M. Mehdi, Joanne Tesiram, Meghna Talekar, Jamie Rossjohn, Hugh H. Reid, Frederik E. Stuurman, Helen Roberts, Phillip Vecchio, Ian Gourley, Mark Rigby, Stephane Becart, Rene E.M. Toes, Hans Ulrich Scherer, Kim-Anh Lê Cao, Kim Campbell, Ranjeny Thomas
Publikováno v:
JCI Insight, Vol 7, Iss 20 (2022)
BACKGROUND Antigen-specific regulation of autoimmune disease is a major goal. In seropositive rheumatoid arthritis (RA), T cell help to autoreactive B cells matures the citrullinated (Cit) antigen-specific immune response, generating RA-specific V do
Externí odkaz:
https://doaj.org/article/25d3db325866461e8778f8d46b427806
Autor:
Josephina P. M. Vrouwe, Ingrid M. C. Kamerling, Michiel J. vanEsdonk, Josbert M. Metselaar, Frederik E. Stuurman, Gabri van derPluijm, Jacobus Burggraaf, Susanne Osanto
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 5, Pp n/a-n/a (2021)
Abstract Dexamethasone has antitumor activity in metastatic castration resistant prostate cancer (mCRPC). We aimed to investigate intravenous liposome‐encapsulated dexamethasone disodium phosphate (liposomal dexamethasone) administration in mCRPC p
Externí odkaz:
https://doaj.org/article/7f6f12eb65c74ad0b8cee9f1481033da
Autor:
Ahnjili ZhuParris, Matthijs D. Kruizinga, Max van Gent, Eva Dessing, Vasileios Exadaktylos, Robert Jan Doll, Frederik E. Stuurman, Gertjan A. Driessen, Adam F. Cohen
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Introduction: The duration and frequency of crying of an infant can be indicative of its health. Manual tracking and labeling of crying is laborious, subjective, and sometimes inaccurate. The aim of this study was to develop and technically validate
Externí odkaz:
https://doaj.org/article/92ada131bdd64d0396f1b07f430f173a
Autor:
Jeroen J. M. A. Hendrikx, Frederik E. Stuurman, Ji‐Ying Song, Vincent A. deWeger, Jurjen S. Lagas, Hilde Rosing, Jos H. Beijnen, Alfred H. Schinkel, Jan H. M. Schellens, Serena Marchetti
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 4, Pp n/a-n/a (2020)
Abstract Oral administration of docetaxel in combination with the CYP3A4 inhibitor ritonavir is used in clinical trials to improve oral bioavailability of docetaxel. Diarrhea was the most commonly observed and dose‐limiting toxicity. This study com
Externí odkaz:
https://doaj.org/article/312864ef1c70464298e06dea8e715675
Autor:
Matthijs D. Kruizinga, Ahnjili Zhuparris, Eva Dessing, Fas J. Krol, Arwen J. Sprij, Robert‐Jan Doll, Frederik E. Stuurman, Vasileios Exadaktylos, Gertjan J. A. Driessen, Adam F. Cohen
Publikováno v:
Pediatric Pulmonology, 57(3), 761-767. Pediatric Pulmonology
Pediatric Pulmonology, 57(3), 761-767. Wiley
Pediatric Pulmonology, 57(3), 761-767. Wiley
IntroductionCoughing is a common symptom in pediatric lung disease and cough frequency has been shown to be correlated to disease activity in several conditions. Automated cough detection could provide a noninvasive digital biomarker for pediatric cl
Autor:
Jules A A C Heuberger, Pim Gal, Frederik E Stuurman, Wouter A S de Muinck Keizer, Yuri Mejia Miranda, Adam F Cohen
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206846 (2018)
INTRODUCTION:Blood lactate concentration rises exponentially during graded exercise when muscles produce more lactate than the body can remove, and the blood lactate-related thresholds are parameters based on this curve used to evaluate performance l
Externí odkaz:
https://doaj.org/article/30c4423e06d14664b4adbf97e507d24e
Autor:
Adam F. Cohen, Gertjan J. Driessen, Matthijs D. Kruizinga, Frederik E. Stuurman, Ahnjili Zhuparris, Marianne Nuijsink, Allison Moll, Dimitrios Ziagkos
Publikováno v:
Respiration
Respiration, 100(10), 979-988. Karger
Respiration, 100(10), 979-988. Karger
Background: Pediatric patients admitted for acute lung disease are treated and monitored in the hospital, after which full recovery is achieved at home. Many studies report in-hospital recovery, but little is known regarding the time to full recovery
Autor:
Matthijs D. Kruizinga, Esmée Essers, Frederik E. Stuurman, Yalçin Yavuz, Marieke L. de Kam, Ahnjili Zhuparris, Hettie M. Janssens, Iris Groothuis, Arwen J. Sprij, Marianne Nuijsink, Adam F. Cohen, Gertjan J.A. Driessen
Publikováno v:
The European respiratory journal, 59(6):2100208. European Respiratory Society
European Respiratory Journal, 59(6):2100208. European Respiratory Society
European Respiratory Journal, 59(6):2100208. European Respiratory Society
BackgroundDigital biomarkers are a promising novel method to capture clinical data in a home setting. However, clinical validation prior to implementation is of vital importance. The aim of this study was to clinically validate physical activity, hea