Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Frederik Rombouts"'
Autor:
Deborah Dhuyvetter, Fetene Tekle, Maxim Nazarov, Rob J. Vreeken, Herman Borghys, Frederik Rombouts, Ilse Lenaerts, Astrid Bottelbergs
Publikováno v:
Drug Delivery, Vol 27, Iss 1, Pp 1597-1607 (2020)
The blood–brain barrier (BBB) is often a limiting factor for getting drugs in the brain. Bypassing the BBB by intranasal (IN), or also called nose to brain (NTB), route is an interesting and frequently investigated concept for brain drug delivery.
Externí odkaz:
https://doaj.org/article/3a2c73fb65e34179bd76465154cdf0e3
Autor:
Mary-Ambre, Carvalho, Samuël, Demin, Carolina, Martinez-Lamenca, Fedor, Romanov-Michailidis, Kevin, Lam, Frederik, Rombouts, Morgan, Lecomte
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 28(1)
Nitriles are recurring motifs in bioactive molecules and versatile functional groups in synthetic chemistry. Despite recent progress, direct introduction of a nitrile moiety in heteroarenes remains challenging. Recent developments in electrochemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78d77f0a626061417bb07699c86f0157
https://pubmed.ncbi.nlm.nih.gov/34658083
https://pubmed.ncbi.nlm.nih.gov/34658083
Autor:
Lieven, Declercq, Frederik, Rombouts, Michel, Koole, Katleen, Fierens, Jonas, Mariën, Xavier, Langlois, José Ignacio, Andrés, Mark, Schmidt, Gregor, Macdonald, Diederik, Moechars, Wim, Vanduffel, Thomas, Tousseyn, Rik, Vandenberghe, Koen, Van Laere, Alfons, Verbruggen, Guy, Bormans
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 58(6)
In this study, we have synthesized and evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6cc34f82b482c81287e9cb9fabe2af3c
https://pubmed.ncbi.nlm.nih.gov/28232614
https://pubmed.ncbi.nlm.nih.gov/28232614
Autor:
Carolina Martinez‐Lamenca, Chiara Zavattaro, Mirielle Braeken, Dennis Franken, Andrés A. Trabanco, Jinsheng Chen, Frederik Rombouts
Publikováno v:
Tetrahedron Letters. 51:4815-4818
A new and facile microwave-assisted protocol for the debenzylation of N-benzylamides with triflic acid has been developed. Both secondary and tertiary aliphatic or aromatic amides are obtained in moderate to good yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46b6fe4cd75ca3526bd70f7bf6405807
https://doi.org/10.1016/j.tetlet.2010.07.022
https://doi.org/10.1016/j.tetlet.2010.07.022
Publikováno v:
Organic letters. 14(7)
Solid-supported organotrifluoroborates were prepared in high yields by ion exchange with Amberlyst resins. The reactivity of solid supported aryltrifluoroborates was evaluated in Suzuki–Miyaura couplings with numerous aryl bromide partners. Electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707763b1fc23ad3eecda14bfb529bf1a
https://pubmed.ncbi.nlm.nih.gov/22404451
https://pubmed.ncbi.nlm.nih.gov/22404451
Autor:
Jinsheng Chen, Mirielle Braeken, Frederik Rombouts, Dennis Franken, Carolina Martinez‐Lamenca, Chiara Zavattaro, Andrés A. Trabanco
Publikováno v:
ChemInform. 41
A new and facile microwave-assisted protocol for the debenzylation of N-benzylamides with triflic acid has been developed. Both secondary and tertiary aliphatic or aromatic amides are obtained in moderate to good yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2261a2404321f7c7bb7937edf84fae5
https://doi.org/10.1002/chin.201051047
https://doi.org/10.1002/chin.201051047
Publikováno v:
Journal of Medicinal Chemistry; Jun2015, Vol. 58 Issue 11, p4365-4382, 18p
Publikováno v:
Journal of the Peripheral Nervous System. Oct2023 Supplement 1, Vol. 28, pS3-S254. 252p.
Autor:
Carvalho, Mary‐Ambre1 (AUTHOR), Demin, Samuël1 (AUTHOR), Martinez‐Lamenca, Carolina1 (AUTHOR), Romanov‐Michailidis, Fedor1 (AUTHOR), Lam, Kevin2 (AUTHOR), Rombouts, Frederik1 (AUTHOR) frombout@its.jnj.com, Lecomte, Morgan1 (AUTHOR) mlecomte@its.jnj.com
Publikováno v:
Chemistry - A European Journal. 1/3/2022, Vol. 28 Issue 1, p1-6. 6p.
Autor:
Dhuyvetter, Deborah1 (AUTHOR), Tekle, Fetene2 (AUTHOR), Nazarov, Maxim3 (AUTHOR), Vreeken, Rob J.4 (AUTHOR), Borghys, Herman1 (AUTHOR), Rombouts, Frederik5 (AUTHOR), Lenaerts, Ilse5 (AUTHOR), Bottelbergs, Astrid5 (AUTHOR)
Publikováno v:
Drug Delivery. Dec2020, Vol. 27 Issue 1, p1597-1607. 11p.