Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Frederik, Diness"'
Autor:
Phillip Miguel Kofoed, Anna A. Hoser, Frederik Diness, Silvia C. Capelli, Anders Østergaard Madsen
Publikováno v:
IUCrJ, Vol 6, Iss 4, Pp 558-571 (2019)
In this contribution we attempt to answer a general question: can X-ray diffraction data combined with theoretical computations be a source of information about the thermodynamic properties of a given system? Newly collected sets of high-quality mult
Externí odkaz:
https://doaj.org/article/fcc901f172ff4d0e94ffb45b9b645264
Autor:
Hongxia Hu, Christian Kofoed, Ming Li, Juliana Pereira Lopes Gonçalves, Jonas Hansen, Martin Wolfram, Axel Kornerup Hansen, Camilla Hartmann Friis Hansen, Frederik Diness, Sanne Schoffelen, Morten Meldal
Publikováno v:
ACS Central Science, Vol 5, Iss 2, Pp 259-269 (2019)
Externí odkaz:
https://doaj.org/article/df07871a47634d12b594183b96701d81
Publikováno v:
Biomaterials Science. 11:719-748
Ribosomally expressed proteins perform multiple, versatile, and specialized tasks throughout Nature. In modern times, chemically modified proteins, including improved hormones, enzymes, and antibody-drug-conjugates have become available and have foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d6675cbf107d5ae90fea1735a14946
https://doi.org/10.1039/d2bm01237e
https://doi.org/10.1039/d2bm01237e
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 523-530 (2018)
Reactivity studies of strong organic acids based on the replacement of one or both of the oxygens in benzoic acids with the trifluoromethanesulfonamide group are reported. Novel derivatives of these types of acids were synthesized in good yields. The
Externí odkaz:
https://doaj.org/article/722c3d60db6e48b681b0e87dc7fbd7ad
Publikováno v:
Fischer, N H, van den Broek, S I L I, Herth, M M & Diness, F 2022, ' Radiolabeled albumin through S N Ar of cysteines as a potential pretargeting theranostic agent ', RSC Advances, vol. 12, no. 54, pp. 35032-35036 . https://doi.org/10.1039/d2ra06406e
Human serum albumin (HSA) has been shown to be a promising tumor targeting vector and target for generating theranostics by bioconjugation. Unstable chemical conjugation to HSA via a cysteine (Cys34) by reversible Michael additions is most commonly a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d285339dcd6b932dd5aa95926f7756
https://doi.org/10.1039/d2ra06406e
https://doi.org/10.1039/d2ra06406e
Autor:
Yang Yang, Niklas Henrik Fischer, Maria Teresa Oliveira, Gul Barg Hadaf, Jian Liu, Theis Brock-Nannestad, Frederik Diness, Ji-Woong Lee
Publikováno v:
Organic & Biomolecular Chemistry. 20:4526-4533
Sulphur-selective conjugate addition reactions play a central role in synthetic chemistry and chemical biology. A general tool for conjugate addition reactions should provide high selectivity in the presence of competing nucleophilic functional group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6954a4ed1c0a97d6357564eafc80ee3f
https://doi.org/10.1039/d2ob00831a
https://doi.org/10.1039/d2ob00831a
Publikováno v:
Chemical Communications. 57:895-898
Solid-phase synthesis of peptides (SPPS) with release through formation of C-terminal γ-, δ-, or ε-lactams is presented. The natural products ciliatamide A and C were synthesized in up to 90% yield. Peptides carrying C-terminal lactams were shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fb56ecdd9223105017f6faa031df6c
https://doi.org/10.1039/d0cc06018f
https://doi.org/10.1039/d0cc06018f
Autor:
Daniel H. Madsen, Andrej Thompson, Frederik Diness, Maria Teresa Oliveira, Yuanyuan Wang, Morten Meldal
Publikováno v:
Chemistry – A European Journal. 26:15825-15829
A variant of the A3 coupling reaction was developed utilizing in situ generated N-carbamoyliminium ions. The tandem INCIC/A3 -coupling sequence provided a facile one-pot synthesis of dihydroquinazolinone derivatives. The scope of the reaction was dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::384e3e1baab1974fbefbfcca45d36726
https://doi.org/10.1002/chem.202003117
https://doi.org/10.1002/chem.202003117
Autor:
Frederik Diness, Morten Meldal
Publikováno v:
Trends in Chemistry. 2:569-584
CuAAC chemistry is used to compose incredible synthetic molecular architectures and acts as a true click chemistry reaction allowing densely functional molecular fragments to be joined in a highly controlled manner. Using supercatalysts based on our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d508d32a13fc135223bb6327aa2924
https://doi.org/10.1016/j.trechm.2020.03.007
https://doi.org/10.1016/j.trechm.2020.03.007
Publikováno v:
Nikitin, S, Lie, Y & Diness, F 2022, ' Lignin-Inspired Polybenzylethersulfone Synthesis via S N Ar Reaction ', Macromolecular Chemistry and Physics, vol. 223, no. 13, pp. 2100484 . https://doi.org/10.1002/macp.202100484
A new type of lignin-inspired polybenzylethersulfone (PBES) is synthesized by SNAr reaction in 75% yield. Success of the polymerization is confirmed by ATR-IR, 1H, 13C NMR spectroscopy and MALDI-TOF MS. The obtained polysulfone is solvent casted into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc62c560a724ce89e55456e879c34bc
https://curis.ku.dk/ws/files/318034851/Macro_Chemistry_Physics_2022_Nikitin_Lignin_u2010Inspired_Polybenzylethersulfone_Synthesis_via_SNAr_Reaction.pdf
https://curis.ku.dk/ws/files/318034851/Macro_Chemistry_Physics_2022_Nikitin_Lignin_u2010Inspired_Polybenzylethersulfone_Synthesis_via_SNAr_Reaction.pdf
