Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Frederico Severino Martins"'
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 876 (2024)
Bioequivalence studies are pivotal in generic drug development wherein therapeutic equivalence is provided with an innovator product. However, bioequivalence studies represent significant complexities due to the interplay of multiple factors related
Externí odkaz:
https://doaj.org/article/8b2b97b7b6c94d8384c6b9e8d5b46e52
Autor:
Nayara Helisandra Fedrigo, Danielle Rosani Shinohara, Josmar Mazucheli, Sheila Alexandra Belini Nishiyama, Floristher Elaine Carrara-Marroni, Frederico Severino Martins, Peijuan Zhu, Mingming Yu, Sherwin Kenneth B. Sy, Maria Cristina Bronharo Tognim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The emergence of polymyxin resistance in Gram-negative bacteria infections has motivated the use of combination therapy. This study determined the mutant selection window (MSW) of polymyxin B alone and in combination with meropenem and fosfo
Externí odkaz:
https://doaj.org/article/1982216eca7d4de6a53da43ee6b273c2
Autor:
Leonardo Luiz Borges, Frederico Severino Martins, João José Franco, Elisa Flávia Luiz Cardoso Bailão, Wilson de Melo Cruvinel, Sérgio Akira Uyemura, Edemilson Cardoso da Conceição
Publikováno v:
Brazilian Journal of Biology, Vol 83 (2021)
Abstract Plinia cauliflora (Mart.) Kausel, popularly known as jabuticaba, is rich in polyphenols. Phenolic compounds exhibit several biological properties, which reflect on biomarkers such as biochemical parameters. In the present study, we evaluated
Externí odkaz:
https://doaj.org/article/5671249537844737aba49744a931fbdd
Autor:
Karinna Bannach Reis, Marcio Vinicius de Carvalho Barros Côrtes, Frederico Severino Martins, Marta Cristina Corsi de Filippi, José Realino de Paula, Edemilson Cardoso da Conceição
Publikováno v:
Pesquisa Agropecuária Brasileira, Vol 50, Iss 12, Pp 1121-1130 (2015)
Abstract: The objective of this work was to purify and standardize the rue (Ruta graveolens) extract and evaluate its effect on Magnaporthe oryzae as an alternative to the integrated management of rice blast. The drug was characterized, the liquid ex
Externí odkaz:
https://doaj.org/article/29b45bbf9f7341ea9eec10282f67c859
Autor:
Ezequiane Machado Silva Oliveira, Sabrine Lemes Freitas, Frederico Severino Martins, Renê Oliveira Couto, Mariana Viana Pinto, José Realino Paula, Edemilson Cardoso Conceição, Maria Teresa Freitas Bara
Publikováno v:
Química Nova, Vol 35, Iss 5, Pp 1041-1045 (2012)
Prior to obtain a standardized dried extract from V. ferruginea, lupeol was first time isolated from leaves and used as chemical maker. An analytical method using HPLC-PDA for lupeol determination in V. ferruginea intermediate products was developed
Externí odkaz:
https://doaj.org/article/2df8a2a7a0e94e8080f98b8d7fe7fb68
Autor:
Frederico Severino Martins
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
O objetivo do presente trabalho foi avaliar a ação melanogênica das furanocumarinas, psoraleno e bergapteno assim como do extrato seco das raízes de Brosimum gaudichaudii Trécul, contendo 1,2 % m/m de psoraleno, e 5,2 % m/m de bergapteno. A toxi
Autor:
Frederico Severino Martins, José Eduardo Severino Martins, Patricia Severino, Pieter Annaert, Sherwin K. B. Sy
Publikováno v:
British Journal of Clinical Pharmacology.
Publikováno v:
British Journal of Clinical Pharmacology. 87:1012-1023
Aims The objective of the current study was to evaluate paediatric dosing regimens for meropenem plus fosfomycin that generate sufficient coverage against multidrug-resistant bacteria. Methods The physiologically based pharmacokinetic (PBPK) models o
Autor:
Maria José Vieira Fonseca, Frederico Severino Martins, Edemilson Cardoso da Conceição, Sherwin K. B. Sy, Osvaldo de Freitas
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Brosimum gaudichaudii Trecul, Moraceae, is a Brazilian plant species used in traditional medicine to treat vitiligo or as an additive in natural suntan lotions. Even though it is widely used in Brazil, its safety and efficacy have not been studied. I
Autor:
Frederico Severino Martins, Sérgio Akira Uyemura, Elisa Flávia Luiz Cardoso Bailão, João José Franco, Edemilson Cardoso da Conceição, Wilson de Melo Cruvinel, Leonardo Luiz Borges
Publikováno v:
Brazilian Journal of Biology, Volume: 83, Article number: e242439, Published: 27 AUG 2021
Brazilian Journal of Biology v.83 2023
Brazilian Journal of Biology
Instituto Internacional de Ecologia (IIE)
instacron:IIE
Brazilian Journal of Biology, Vol 83 (2021)
Brazilian Journal of Biology v.83 2023
Brazilian Journal of Biology
Instituto Internacional de Ecologia (IIE)
instacron:IIE
Brazilian Journal of Biology, Vol 83 (2021)
Plinia cauliflora (Mart.) Kausel, popularly known as jabuticaba, is rich in polyphenols. Phenolic compounds exhibit several biological properties, which reflect on biomarkers such as biochemical parameters. In the present study, we evaluated the plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41367ba19db27208a2763b44fe0efba1
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842023000100173&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842023000100173&lng=en&tlng=en