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pro vyhledávání: '"Frederick W. Holtzberg"'
Autor:
John S. Bomalaski, C. Mark Ensor, Maurizio Montella, Gerardo Beneduce, Guglielmo Nasti, Fabrizio Scordino, Antonio Pio Orlando, Mike A. Clark, F. Cremona, Raffaele Orlando, Giuseppe Castello, Frederick W. Holtzberg, Francesco Izzo, Brent E. Korba, Steven A. Curley
Publikováno v:
Journal of Gastroenterology and Hepatology. 22:86-91
Background: The arginine-degrading enzyme, arginine deiminase conjugated to polyethylene glycol (ADI-SS PEG 20 000 mw), reduces extracellular arginine, has minimal toxicity, decreases tumor burden and improves liver function in patients with chronic