Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Frederick W. Flitney"'
Autor:
Frederick W. Flitney, Melissa G. Mendez, Boris Grin, Lynne Chang, Robert D. Goldman, Ying-Hao Chou
Publikováno v:
Experimental Cell Research. 313:2236-2243
Intermediate filament (IF) proteins exist in multiple structural forms within cells including mature IF, short filaments or 'squiggles', and non-filamentous precursors called particles. These forms are interconvertible and their relative abundance is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd13f3e86bc1550ab35ed9bb2750c029
https://doi.org/10.1016/j.yexcr.2007.04.008
https://doi.org/10.1016/j.yexcr.2007.04.008
Autor:
Ronald T. Hay, Frederick W. Flitney, Catherine Beers, Vicky Cameron, Lesley Thomson, David C. Hay
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1642(1-2):33-44
The tractive force generated by blood flow, called fluid shear stress, is an important regulator of endothelial cell gene expression. Several transcription factors are activated by shear stress, including members of the NF-kappaB/Rel family. The natu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e142cc7498722ceb2b2ed4ac65410dbb
Autor:
Frederick W. Flitney, Robert D. Goldman, Miri Yoon, Robert D. Moir, Satya Khuon, Kyeong Han Yoon
Publikováno v:
The Journal of Cell Biology
The properties of keratin intermediate filaments (IFs) have been studied after transfection with green fluorescent protein (GFP)-tagged K18 and/or K8 (type I/II IF proteins). GFP-K8 and -K18 become incorporated into tonofibrils, which are comprised o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09457e8894884058cef55663f8a314d0
http://europepmc.org/articles/PMC2190576
http://europepmc.org/articles/PMC2190576
Publikováno v:
British Journal of Pharmacology. 130:1575-1580
Photorelaxation of vascular smooth muscle (VSM) is caused by the release of nitric oxide (NO) from a finite molecular store that can be depleted by irradiating pre-contracted arteries with visible light. The ability of an ‘exhausted’ vessel to re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2671cb746b53808212a9fb6e636acda0
https://doi.org/10.1038/sj.bjp.0703499
https://doi.org/10.1038/sj.bjp.0703499
Autor:
Elizabeth Slade, Frederick W. Flitney, Nigel A. Powell, Ian L. Megson, O. J. Vaughan, Simon P. Fricker, Stuart K Bisland, Barry A. Murrer, Graham R. Henderson
Publikováno v:
British Journal of Pharmacology. 122:1441-1449
1 Ruthenium(III) reacts with nitric oxide (NO) to form stable ruthenium(II) mononitrosyls. Several Ru(III) complexes were synthesized and a study made of their ability to bind NO, in vitro and also in several biological systems following expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ee15878ab2b0c102774ffebac8e2c03
https://doi.org/10.1038/sj.bjp.0701504
https://doi.org/10.1038/sj.bjp.0701504
Autor:
Ian L. Megson, Frederick W. Flitney, Anthony R. Butler, Stuart K Bisland, Haitham H. Al-Sa'doni
Publikováno v:
British Journal of Pharmacology. 121:1047-1050
A study has been made of the effect of neocuproine, a specific Cu(I) chelator, on vasodilator responses of rat isolated perfused tail artery to two nitrosothiols: S-nitroso-N-acetyl-d,l-penicillamine (SNAP) and S-nitroso-glutathione (GSNO). Bolus inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::344fd68dcd141855022a7f380137586b
https://doi.org/10.1038/sj.bjp.0701218
https://doi.org/10.1038/sj.bjp.0701218
Publikováno v:
British Journal of Pharmacology. 117:1549-1557
1. The vasodilator properties and photochemical decomposition of two synthetic iron-sulphur-nitrosyl clusters (cluster A: [Fe4S4(NO)4], tetranitrosyl-tetra-mu 3-sulphido-tetrahedro-tetrairon; and B:[Fe4S3 (NO)7]-1, heptanitrosyl-tri-mu 3-thioxotetraf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3257f6556dd8b39b4eb2ce7f856d19b
https://doi.org/10.1111/j.1476-5381.1996.tb15320.x
https://doi.org/10.1111/j.1476-5381.1996.tb15320.x
Publikováno v:
Trends in Pharmacological Sciences. 16:18-22
The multiplicity of biological functions thus far attributed to NO has led to suggestions that some effects might be mediated by other, related species instead. The radical nature of NO cannot account for its cytotoxicity, but its reaction with super
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df5f998fc867b9d1c5e1bb6d2b57ebe
https://doi.org/10.1016/s0165-6147(00)88968-3
https://doi.org/10.1016/s0165-6147(00)88968-3
Autor:
Rebecca J Pritchard, Simon Fricker, Stuart K Bisland, Gordon D. Kennovin, David G. Hirst, Frederick W. Flitney
Publikováno v:
Molecular cancer therapeutics. 10(9)
The role of endogenous nitric oxide (NO) in the growth and vascularization of a rat carcinosarcoma (P22) has been investigated. Tumor-bearing animals were treated with (i) nitric oxide synthase (NOS) inhibitors, administered via the drinking water, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3940ae6b1797abd91ed237961b7aced
https://pubmed.ncbi.nlm.nih.gov/21712476
https://pubmed.ncbi.nlm.nih.gov/21712476
Publikováno v:
British Journal of Pharmacology. 107:842-848
1. Two iron-sulphur cluster nitrosyls have been investigated as potential nitric oxide (NO.) donor drugs (A: tetranitrosyltetra-mu 3-sulphidotetrahedro-tetrairon; and B: heptanitrosyltri-mu 3-thioxotetraferrate(1-)). Both compounds are shown to dilat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65338d2c529b22a7a49b54b540d6903
https://doi.org/10.1111/j.1476-5381.1992.tb14534.x
https://doi.org/10.1111/j.1476-5381.1992.tb14534.x