Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Frederick T. Fiedorek"'
Publikováno v:
Genomics. 49:152-155
CYP2J subfamily cytochromes P450 catalyze the NADPH-dependent oxidation of arachidonic acid to several unique eicosanoids that possess numerous biological activities including modulation of ion transport, control of bronchial and vascular smooth musc
Autor:
Roger W. Wiseman, Astrid Haugen-Strano, Charles Cochran, Frederick T. Fiedorek, Bennett Lm, Brownlee Ha
Publikováno v:
Genomics. 29:576-581
The BRCA1 gene is in large part responsible for hereditary human breast and ovarian cancer. Here we report the isolation of the murine Brca1 homologue cDNA clones. In addition, we identified genomic P1 clones that contain most, if not all, of the mou
Autor:
Raymond E. Bourey, Mike Mueckler, David E. James, M. Alan Permutt, László Korányi, Frederick T. Fiedorek
Publikováno v:
Molecular and Cellular Neuroscience. 2:244-252
Steady-state levels of the major glucose transporter gene (GLUT-1) of the brain were evaluated under three conditions that induced chronic changes in plasma glucose and insulin in adult rats: (i) repeated injection of insulin for 5 days, resulting in
Publikováno v:
Molecular Endocrinology. 4:990-999
Four rat insulinoma-derived cell lines were found to express only the rat insulin I gene, although an apparently normal insulin II gene was present in each cell line. This finding was reflected by the absence of insulin II and the presence of insulin
Autor:
Sherin U. Devaskar, Daphne E. deMello, Robert E Schroeder, Uday P. Devaskar, Frederick T. Fiedorek, Mike Mueckler
Publikováno v:
American journal of obstetrics and gynecology. 171(5)
Maternal diabetes alters placental glucose metabolism and maternofetal glucose transport. The purpose of this study was to determine whether genes involved in placental glucose uptake and transport were concomitantly altered, resulting in the observe
Autor:
Frederick T. Fiedorek, David Parkinson
Publikováno v:
Endocrinology. 131(3)
Carboxypeptidase H (CP-H, EC 3.4.17.10) removes C-terminal basic amino acids from insulin and many other peptide hormone intermediates in endocrine and neural tissues. CP-H was studied in two rat insulinoma-derived clonal beta-cell lines that were ch
Autor:
Frederick T. Fiedorek, Donald E. Kohan
Publikováno v:
Journal of the American Society of Nephrology : JASN. 2(2)
Endothelin has been shown to affect a broad range of renal functions, including rat inner medullary collecting duct Na/K ATPase activity, renin release, renal blood flow, and glomerular filtration rate. The source of endothelin in the kidney has been
Autor:
Andrew Maxwell Tonkin, Bertram Pitt, Frederick T. Fiedorek, Chen Sheng-Lin, Donald A Berry, Frank M. Sacks, Andrew J. Walker, Neville F. Ford, Robert P. Byington, Charles H. Hennekens, J. Wouter Jukema, Rene Belder, Kannan Natarajan, Scott Berry
Publikováno v:
Archives of Internal Medicine. 164:40
Background In randomized trials of secondary prevention, pravastatin sodium and aspirin reduce risks of cardiovascular disease. Pravastatin has a predominantly delayed antiatherogenic effect, and aspirin has an immediate antiplatelet effect, raising
Autor:
Donald A. Berry, Andrew Tonkin, Andrew J. Walker, Wouter Jukema, Frederick T. Fiedorek, Chen Sheng-Lin, Rene Belder, Charles H. Hennekens, Bertram Pitt, Scott M. Berry, Kannan Natarajan, Frank M. Sacks, Neville F. Ford, Robert P. Byington
Publikováno v:
Journal of the American College of Cardiology. 41:526