Zobrazeno 1 - 5 of 5 pro vyhledávání: '"Frederick T. Clark"'
1
Identification and expression cloning of a leptin receptor, OB-R
Autor: Robert I. Tepper, Sean Sanker, Karen J. Moore, Jim Deeds, Janice A. Culpepper, Gail G. Mays, Nanhua Deng, Marlene Dembski, Rene Devos, Craig Muir, L. Arthur Campfield, John S. Smutko, Louis A. Tartaglia, Frederick T. Clark, Grayson J. Richards, Ann Moriarty, Elizabeth A. Wool, Cheryl A. Monroe, Xun Weng
Publikováno v: Cell. 83(7)
The ob gene product, leptin, is an important circulating signal for the regulation of body weight. To identify high affinity leptin-binding sites, we generated a series of leptin-alkaline phosphatase (AP) fusion proteins as well as [125I]leptin. Afte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32692e37a7c523595058c446a0d5523
https://pubmed.ncbi.nlm.nih.gov/15055599
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2
Alanine substitution of two arginines in amino terminus of V3 of SIV disrupts CD4 binding whereas a similar replacement of two amino acids, lysine and arginine, in the carboxyl half of V3 prevents binding of a neutralizing monoclonal antibody
Autor: Lynn Zuchowski, Kashi Javaherian, Frederick T. Clark
Publikováno v: AIDS research and human retroviruses. 11(9)
A series of amino acid substitutions were carried out in the V3 loop of SIV gpl20 to investigate their effects on binding of the envelope to CD4 and neutralizing monoclonal antibodies. Alanine replacement of two adjacent arginines at the amino termin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54e094bfdaf58676d5345478f2ee2bf
https://pubmed.ncbi.nlm.nih.gov/8554907
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Plný text Recenzováno Digitální knihovna AV ČR
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