Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Frederick S. Buckner"'
Autor:
Thao T. Truong, Karissa Crawford, Ichih Wang-McGuire, Kendal Jensen, Aisha Mushtaq, Nicole A. P. Lieberman, Frederick S. Buckner, Wesley C. Van Voorhis, Brad T. Cookson, Stephen J. Salipante, Joshua A. Lieberman
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT Leishmaniasis is a rare disease in the United States, with an estimated annual incidence of dozens of cases occurring primarily in travelers, migrants, and military personnel. True disease incidence is unknown, since leishmaniasis is not a n
Externí odkaz:
https://doaj.org/article/ea705f21d419493a84fac5e5d369c85f
Autor:
Frederick S. Buckner
Publikováno v:
EBioMedicine, Vol 64, Iss , Pp 103188- (2021)
Externí odkaz:
https://doaj.org/article/234c15b4555c432988abac4308fc76b5
Autor:
Alexandra Probst, Thi N. Nguyen, Nelly El-Sakkary, Danielle Skinner, Brian M. Suzuki, Frederick S. Buckner, Michael H. Gelb, Conor R. Caffrey, Anjan Debnath
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
The protozoan parasite Entamoeba histolytica can induce amebic colitis and amebic liver abscess. First-line drugs for the treatment of amebiasis are nitroimidazoles, particularly metronidazole. Metronidazole has side effects and potential drug resist
Externí odkaz:
https://doaj.org/article/c2d0be25852b45c0916199092e9373e5
Autor:
Frederick S. Buckner, Andriy Buchynskyy, Pendem Nagendar, Donald A. Patrick, J. Robert Gillespie, Zackary Herbst, Richard R. Tidwell, Michael H. Gelb
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 5, Iss 1, p 23 (2020)
The work began with the screening of a library of 700,000 small molecules for inhibitors of Trypanosoma brucei growth (a phenotypic screen). The resulting set of 1035 hit compounds was reviewed by a team of medicinal chemists, leading to the nominati
Externí odkaz:
https://doaj.org/article/017ace40eccb475fa72c44de9f674162
Autor:
Richard T. Eastman, Frederick S. Buckner, Kohei Yokoyama, Michael H. Gelb, Wesley C. Van Voorhis
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 2, Pp 233-240 (2006)
Protein farnesylation is a form of posttranslational modification that occurs in most, if not all, eukaryotic cells. Inhibitors of protein farnesyltransferase (PFTIs) have been developed as anticancer chemotherapeutic agents. Using the knowledge gain
Externí odkaz:
https://doaj.org/article/08edbbc938f84fed8845c1384b576395
Autor:
Thao T. Truong, Karissa Crawford, Ichih Wang-McGuire, Kendal Jensen, Aisha Mushtaq, Nicole A.P. Lieberman, Frederick S. Buckner, Wesley C. Van Voorhis, Brad T. Cookson, Stephen J. Salipante, Joshua A. Lieberman
Leishmaniasis is a rare disease in the United States, with an estimated annual incidence of dozens of cases occurring primarily in travelers, migrants, and military personnel. True disease incidence is unknown, since leishmaniasis is not a nationally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::582a8646f7c8ed946b2d1b508dbfd3da
https://doi.org/10.1101/2023.05.23.23290303
https://doi.org/10.1101/2023.05.23.23290303
Autor:
Sarah A. McGuffin, Vidya Atluri, Santiago Neme, Meei-Li Huang, Seth A Cohen, Helen Y. Chu, Frederick S. Buckner, H. Nina Kim, Denise J. McCulloch, Keith R. Jerome, Alexander L. Greninger, Arun K. Nalla, Michela Blain, Margaret L. Green
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases
Clinical Infectious Diseases
BackgroundWashington State served as the initial epicenter of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in the United States. An understanding of the risk factors and clinical outcomes of hospitalized patients with cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64f72adb281f2a2ea51854377ed5888
https://doi.org/10.1093/cid/ciaa632
https://doi.org/10.1093/cid/ciaa632
Autor:
Frederick S. Buckner, Michael H. Gelb
Publikováno v:
ACS Infect Dis
In this Viewpoint we provide a brief description of two efforts to develop drugs to treat diseases caused by tropical parasites (Malaria, human African trypanosomiasis, and Chagas disease). These efforts are largely based in a University setting but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0a41571fe1fb05ae1e85bd2808064b
https://doi.org/10.1021/acsinfecdis.1c00091
https://doi.org/10.1021/acsinfecdis.1c00091
Publikováno v:
Neglected Tropical Diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0106c9121f0a5dd5217bddd1f237a53
https://doi.org/10.1002/9783527808656.ch6
https://doi.org/10.1002/9783527808656.ch6
Autor:
Erkang Fan, Jose E. Teixeira, Adam Sateriale, Christopher D. Huston, John R. Gillespie, Peter Jonathon Miller, Muhammad M. Hasan, Erin E. Stebbins, Frederick S. Buckner, Zhongsheng Zhang, Robert K. M. Choy, Christophe L. M. J. Verlinde, Ranae M. Ranade, Eugenio L. de Hostos, Aisha Mushtaq, Damon M. Osbourn, David W. Griggs
Publikováno v:
Antimicrob Agents Chemother
The intestinal protozoan Cryptosporidium is a leading cause of diarrheal disease and mortality in young children. There is currently no fully effective treatment for cryptosporidiosis, which has stimulated interest in anticryptosporidial development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9d4e0b2a43263d5bede9707a02798d
https://doi.org/10.1128/aac.00023-21
https://doi.org/10.1128/aac.00023-21