Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Frederick S Buckner"'
Autor:
Paul Kelly, William A Petri, Rashidul Haque, Ibrahim A Khalil, Lynn Barrett, Tom Kennedy, Timothy Wells, Christopher D Huston, James Platts-mills, Grace S Yang, Richard Omore, Ian H Gilbert, Sumiti Vinayak, Boris Striepen, Ujjini H Manjunatha, Wesley C Van Voorhis, Samuel L M Arnold, Beatriz Baragana, Frederick S Buckner, Jeremy D Burrows, Maria A Caravedo, Ryan Choi, Robert K M Choy, Eugenio de Hostos, Thierry Diagana, Suzanne Duce, Matthew A Hulverson, Pui-Ying Iroh Tam, Minju Kim, Poonum Korpe, Benoît Laleu, Diana Lalika, Fabrice Laurent, Case W McNamara, Marvin J Meyers, Roberta M O’Connor, Kayode K Ojo, Philipp Olias, Nede Ovbiebo, Mattie C Pawlowic, Gladys Queen, Divya Rao, Kevin Reed, Michael W Riggs, Jennifer L Roxas, Adam Sateriale, Deborah A Schaefer, L David Sibley, Jonathan M Spector, Chris Tonkin, Timilehin E Toye, Saul Tzipori, A Clinton White
Publikováno v:
BMJ Global Health, Vol 8, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/540e409047fd43baae051b1737c1bbc5
Autor:
Kayode K Ojo, Ranae M Ranade, Zhongsheng Zhang, David M Dranow, Janette B Myers, Ryan Choi, Steve Nakazawa Hewitt, Thomas E Edwards, Douglas R Davies, Donald Lorimer, Stephen M Boyle, Lynn K Barrett, Frederick S Buckner, Erkang Fan, Wesley C Van Voorhis
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160350 (2016)
We investigated Brucella melitensis methionyl-tRNA-synthetase (BmMetRS) with molecular, structural and phenotypic methods to learn if BmMetRS is a promising target for brucellosis drug development. Recombinant BmMetRS was expressed, purified from wil
Externí odkaz:
https://doaj.org/article/cb7e4a5c4ce4461f81768815566850e3
Autor:
Kayode K Ojo, Ranae M Ranade, Zhongsheng Zhang, David M Dranow, Janette B Myers, Ryan Choi, Steve Nakazawa Hewitt, Thomas E Edwards, Douglas R Davies, Donald Lorimer, Stephen M Boyle, Lynn K Barrett, Frederick S Buckner, Erkang Fan, Wesley C Van Voorhis
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163641 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0160350.].
Externí odkaz:
https://doaj.org/article/c92c1f2c13354f3b8fd19714b3ea1027
Synergy testing of FDA-approved drugs identifies potent drug combinations against Trypanosoma cruzi.
Autor:
Joseph D Planer, Matthew A Hulverson, Jennifer A Arif, Ranae M Ranade, Robert Don, Frederick S Buckner
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 7, p e2977 (2014)
An estimated 8 million persons, mainly in Latin America, are infected with Trypanosoma cruzi, the etiologic agent of Chagas disease. Existing antiparasitic drugs for Chagas disease have significant toxicities and suboptimal effectiveness, hence new t
Externí odkaz:
https://doaj.org/article/ba693335c824477fa3bbab1573a1a19d
Autor:
Cho Yeow Koh, Jessica E Kim, Allan B Wetzel, Will J de van der Schueren, Sayaka Shibata, Ranae M Ranade, Jiyun Liu, Zhongsheng Zhang, J Robert Gillespie, Frederick S Buckner, Christophe L M J Verlinde, Erkang Fan, Wim G J Hol
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 4, p e2775 (2014)
Methionyl-tRNA synthetase of Trypanosoma brucei (TbMetRS) is an important target in the development of new antitrypanosomal drugs. The enzyme is essential, highly flexible and displaying a large degree of changes in protein domains and binding pocket
Externí odkaz:
https://doaj.org/article/d5d82033472f498782042305c840c109
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e26508 (2011)
Kinesins are a family of motor proteins conserved throughout eukaryotes. In our present study we characterize a novel kinesin, Kinesin(CaaX), orthologs of which are only found in the kinetoplastids and not other eukaryotes. Kinesin(CaaX) has the CVIM
Externí odkaz:
https://doaj.org/article/86b16673ccaa432b9b8feb577bb64e79
Autor:
Frederick S. Buckner
Publikováno v:
EBioMedicine, Vol 64, Iss , Pp 103188- (2021)
Externí odkaz:
https://doaj.org/article/234c15b4555c432988abac4308fc76b5
Autor:
Thao T. Truong, Karissa Crawford, Ichih Wang-McGuire, Kendal Jensen, Aisha Mushtaq, Nicole A.P. Lieberman, Frederick S. Buckner, Wesley C. Van Voorhis, Brad T. Cookson, Stephen J. Salipante, Joshua A. Lieberman
Leishmaniasis is a rare disease in the United States, with an estimated annual incidence of dozens of cases occurring primarily in travelers, migrants, and military personnel. True disease incidence is unknown, since leishmaniasis is not a nationally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::582a8646f7c8ed946b2d1b508dbfd3da
https://doi.org/10.1101/2023.05.23.23290303
https://doi.org/10.1101/2023.05.23.23290303
Autor:
Sarah A. McGuffin, Vidya Atluri, Santiago Neme, Meei-Li Huang, Seth A Cohen, Helen Y. Chu, Frederick S. Buckner, H. Nina Kim, Denise J. McCulloch, Keith R. Jerome, Alexander L. Greninger, Arun K. Nalla, Michela Blain, Margaret L. Green
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases
Clinical Infectious Diseases
BackgroundWashington State served as the initial epicenter of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in the United States. An understanding of the risk factors and clinical outcomes of hospitalized patients with cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64f72adb281f2a2ea51854377ed5888
https://doi.org/10.1093/cid/ciaa632
https://doi.org/10.1093/cid/ciaa632
Autor:
Frederick S. Buckner, Michael H. Gelb
Publikováno v:
ACS Infect Dis
In this Viewpoint we provide a brief description of two efforts to develop drugs to treat diseases caused by tropical parasites (Malaria, human African trypanosomiasis, and Chagas disease). These efforts are largely based in a University setting but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0a41571fe1fb05ae1e85bd2808064b
https://doi.org/10.1021/acsinfecdis.1c00091
https://doi.org/10.1021/acsinfecdis.1c00091