Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Frederick R. Haselton"'
Autor:
Christia M. Victoriano, Megan E. Pask, Nicole A. Malofsky, Adam Seegmiller, Steve Simmons, Jonathan E. Schmitz, Frederick R. Haselton, Nicholas M. Adams
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract PCR-based diagnostics generally require nucleic acid extraction from patient specimens prior to amplification. As highlighted early in the COVID-19 pandemic, extraction steps may be difficult to scale during times of massive demand and limit
Externí odkaz:
https://doaj.org/article/de69f5555a644c808ef462f0d7e32cc4
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Ovarian cancer has a poor cure rate and rates of relapse are high. Current recurrence detection is limited by non-specific methods such as blood testing and ultrasound. Based on reports that human epididymis four (HE4) / creatinine (CRE) rat
Externí odkaz:
https://doaj.org/article/a73edc14b2374ee8aa07670b68bbbf70
Publikováno v:
Diagnostics, Vol 11, Iss 11, p 2155 (2021)
In developing countries, the most common diagnostic method for tuberculosis (TB) is microscopic examination sputum smears. Current assessment requires time-intensive inspection across the microscope slide area, and this contributes to its poor diagno
Externí odkaz:
https://doaj.org/article/d7a60ff1d9b74e4588ae2c1896b01425
Autor:
Zackary A. Zimmers, Alexander D. Boyd, Hannah E. Stepp, Nicholas M. Adams, Frederick R. Haselton
Publikováno v:
Micromachines, Vol 12, Iss 10, p 1204 (2021)
Among nucleic acid diagnostic strategies, non-enzymatic tests are the most promising for application at the point of care in low-resource settings. They remain relatively under-utilized, however, due to inadequate sensitivity. Inspired by a recent de
Externí odkaz:
https://doaj.org/article/d20f4db2a4b840f79fbbe34a5360458d
Autor:
W. Todd Monroe, Frederick R. Haselton
Publikováno v:
BioTechniques, Vol 34, Iss 1, Pp 68-73 (2003)
A method based on Web-based tools is presented to design optimally functioning molecular beacons. Molecular beacons, fluorogenic hybridization probes, are a powerful tool for the rapid and specific detection of a particular nucleic acid sequence. How
Externí odkaz:
https://doaj.org/article/4ee373a7f6254d76a76ac4a95332c346
Publikováno v:
Cell Transplantation, Vol 14 (2005)
Persistent corneal wounds result from numerous eye disorders, and to date, available treatments often fail to accelerate reepithelialization, the key initial step in wound healing. To speed reepithelialization, we explored a cell-transfer transplant
Externí odkaz:
https://doaj.org/article/8dd16056725547f79bd8835f519415e3
Autor:
Dalton J. Nelson, Meghan H. Shilts, Suman B. Pakala, Suman R. Das, Jonathan E. Schmitz, Frederick R. Haselton
Publikováno v:
Influenza and other respiratory virusesREFERENCES.
COVID-19 prevalence has remained high throughout the pandemic with intermittent surges, due largely to the emergence of genetic variants, demonstrating the need for more accessible sequencing technologies for strain typing.A ligation-based typing ass
Publikováno v:
Optics and Biophotonics in Low-Resource Settings VIII.
Magnetic Bead Processing Enables Sensitive Ligation-Based Detection of HIV Drug Resistance Mutations
Autor:
Dalton J. Nelson, Mindy Leelawong, Megan E. Pask, C. William Wester, Muktar H. Aliyu, Frederick R. Haselton
Publikováno v:
Analytical chemistry. 94(5)
HIV develops single nucleotide polymorphisms (SNPs), some of which lead to drug resistance mutations (DRMs) that prevent therapeutic viral suppression. Genomic sequencing enables healthcare professionals to select effective combination antiretroviral
Autor:
Dalton Jay Nelson, Meghan H. Shilts, Suman B. Pakala, Suman R. Das, Jonathan Schmitz, Frederick R. Haselton
Publikováno v:
SSRN Electronic Journal.