Predictors of Cognitive Decline in Older Adult Type 2 Diabetes from the Veterans Affairs Diabetes Trial

Autor: Csaba Kovesdy, Carol Franko, Julia Passyn-Dunn, Wendy S. Wendel, Kathy Dardick, Cyrus DeSouza, Mary Helen Vasquez, Vanita Aroda, Jessica Devin, Patricia Harris, Adilia Sama, Rabih Hijazi, Andrew L. Taylor, Dereck MaFong, Peter Reaven, Tania Tejera, Dennis Karounos, Sangeeta Kayshup, Sarah Wagstaff, Suzanne Hanna, Leonard Pogach, Anna Chang, Yangheng Fu, Dennis Kim, Steven Edelman, Linda Kollman, Lora Risley, Ling Ge, J. Shin John, Sarah Doran, Paromita Datta, Joseph Yu, Jimenez Maribel Rios, Lorraine Okur, Mary McElmeel, Janice N. Beattie, Sandeep Chaudhary, Robert J. Anderson, Farid Roman, Louie Christiansen, Franklin Zieve, M. Sue Kirkman, As’ad Ehtisham, Charles Choe, Thomas Boyden, Brunilda Padilla, Tess Weaver, Eliot Brinton, Susan J. Clark, Heidi Garcia, Ronald K. Mayfield, David Kelly, Devjit Tripathy, Jayendra H. Shah, Diana Davis, Lynette Fox, Felice Caldarella, Sanjay Gupta, Sonja Fredrickson, Donna Pfeifer, Mariana Garcia Touza, Zehra Haider, Karen L. Moore, Lucille Jones, Al Powers, Martha Mendez, Erica Smith, Joy Clark, Elda Gonzalez-Melendez, Jocelyn Serrano-Rodriguez, John M. Stafford, Robert R. Henry, Steve Ludwig, L. Raymond Reynolds, Clorinda Geldrez, Subramaniam Tavintharan, Tina Rahbarnia, Fabia A. Kwiecinski, Linda Balch, Mark Lupo, Jeremy Soule, Diana Dunning, Marco Marcelli, Paula Harper, Merilyn G. Goldschmidt, Catherine Niewoehner, Andrea Gasper, Annis Marney, Janet Wilson, Constantino Carseli, Juleen Paul, Hermes Florez, Ashraf Iranmanesh, Melisse Maser, Jack E. Allen, Clare Pittman, Greg Moffitt, Bradley Solie, Patricia Linnerud, Nancy Downey, Janet Blodgett, Lynne A. Gurnsey, Ralph DeFronzo, Manju Chandra, Frances Rosenberg, Julio Benabe, R. Harsha Rao, Julius Sagel, Christy Florow, Frederick R. DeRubertis, Diane I. Schroeder, Natalie M. Nichols, Mark B Zimering, Emilia Cordero, Angeliki Georgopoulos, Carlos Rosado, John Matchette, Frank Sanacor, Rahil Bandukwala, George Arakel, Kathleen Kahsen, Miriam Keller, Virginia Easton, Paulette Ginier, Jeffrey Knight, James Levy, Ray Plodkowski, Lisa Johnson, Maria Natal, Gideon Bahn, Jeff Carlsen, Frank Q. Nuttall, Barbara Dunn, Mandeep Bajaj, Ken Cusi, Amale Lteif, Fe Remandaban, Lily Agrawal, Shelley Townes, Roopa Sathyaprakash, Mamta Shah, Lynnette Scott, James W. Anderson, Ann Grimsdale, Nadeem Aslam, Linda Barber, Sylvia Vela, Robert Ecklund, Richard M. Gonzales, Anthony N. Vo, Nasrin Azad, Zuleika Mercado, Elizabeth Ganaway, Edwin Mejias, Claire Korolchuk, Nicholas V. Emanuele, Robert W. Collins, Sunder Mudaliar, Jennifer Perkins, Gina Macaraeg, Paula G. Hensley, Susan Caulder, Alisa Domb, Janet Hibbard, C. Daniel Meyers, Marlene Vogel, Luis Samos, Jennifer Marks, Moti L. Kashyap, Lisa Cupersmith, Stephen N. Davis, Norman Ertel, Omayra Alston, Don Tayloe, Deborah Oh, Barbara Walz, Barbara Matheus, Neelima Chu, Elizabeth Fox, Linda McDonald, Lynae Shurtz, Christina Lazar-Robinson, Ali Iranmanesh, Sithophol Chinnapongse, Donna Arsura, Christian Meyer, Glenn R. Cunningham

Publikováno v: Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 7 (2016)

Aims: Cognitive decline disproportionately affects older adult type 2 diabetes. We tested whether randomized intensive glucose-lowering reduces the rate(s) of cognitive decline in adults with advanced type 2 diabetes (mean: age, 60 years; diabetes du

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5ac0c4184c280c9891227082a8a24d
https://doi.org/10.3389/fendo.2016.00123

Active Care Management Supported by Home Telemonitoring in Veterans With Type 2 Diabetes

Autor: Carol M. Franko, D. Scott Obrosky, Chunrong Cheng, Frederick R. DeRubertis, R Harsha Rao, Linda J. Hough, Rebecca A. Anglin, Roslyn A. Stone, Mary Ann Sevick, David S. Macpherson

Publikováno v: Diabetes Care. 33:478-484

OBJECTIVE We compared the short-term efficacy of home telemonitoring coupled with active medication management by a nurse practitioner with a monthly care coordination telephone call on glycemic control in veterans with type 2 diabetes and entry A1C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba34a10d9ff1fa2c0773737e97d06cad
https://doi.org/10.2337/dc09-1012

α-Lipoic Acid Attenuates Hyperglycemia and Prevents Glomerular Mesangial Matrix Expansion in Diabetes

Autor: Mona F. Melhem, Julia Liachenko, Frederick R. DeRubertis, Patricia A. Craven

Publikováno v: Journal of the American Society of Nephrology. 13:108-116

Previous studies demonstrated that 2 mo of dietary supplementation with alpha-lipoic acid (LA) prevented early glomerular injury in non-insulin-treated streptozotocin diabetic rats (D). The present study examined the effects of chronic LA supplementa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c19e6b152fe4a3e00004d156087fd3
https://doi.org/10.1681/asn.v131108

Nitric Oxide Inhibition of Transforming Growth Factor-β and Collagen Synthesis in Mesangial Cells

Autor: Frederick R. DeRubertis, Rebecca K. Studer, Stephen L. Phillips, Patricia A. Craven, Jill Felder

Publikováno v: Diabetes. 46:671-681

Culture of mesangial cells (MCs) in 5.6 vs. 30.0 mmol/l glucose for 3 weeks induced a sustained increase in protein kinase C (PKC) activity, transforming growth factor (TGF)-beta1 mRNA, bioactive TGF-beta, and collagen synthesis. Nitric oxide (NO), g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbf320a0974a6fbf4e6b2f8e77d7fba
https://doi.org/10.2337/diab.46.4.671

Monoclonal Gammopathy and Spurious Hypophosphatemia

Autor: Steven D. Weisbord, Frederick R. DeRubertis, Anita Chaudhuri, Kathleen Blauth

Publikováno v: The American Journal of the Medical Sciences. 325:98-100

Spuriously low levels of plasma phosphate have been reported previously in patients with multiple myeloma and polyclonal gammopathy. We report 2 cases of spurious hypophosphatemia in patients with elevated concentrations of serum monoclonal immunoglo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efa3d9fad3073a7a3175a5d83947315
https://doi.org/10.1097/00000441-200302000-00007