Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Frederick R Adler"'
Autor:
Thuy T T Le, Frederick R Adler
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 7, p e1008036 (2020)
The benefits of mammography screening have been controversial, with conflicting findings from various studies. We hypothesize that unmeasured heterogeneity in tumor aggressiveness underlies these conflicting results. Based on published data from the
Externí odkaz:
https://doaj.org/article/d48efd161bb74a2c9974dcc589c5e68f
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0199388 (2018)
BACKGROUND:Common cold viruses create significant health and financial burdens, and understanding key loci of transmission would help focus control strategies. This study (1) examines factors that influence when individuals transition from a negative
Externí odkaz:
https://doaj.org/article/4aa550da4f7a4f489790df6b6a01ff14
Autor:
Frederick R Adler, Theodore G Liou
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156752 (2016)
In cystic fibrosis, statistical models have been more successful in predicting mortality than the time course of clinical status. We develop a system of partial differential equations that simultaneously track mortality and patient status, with all m
Externí odkaz:
https://doaj.org/article/d07e4147800546bf9cfc7dc1fda33e2d
Autor:
Damon J A Toth, Adi V Gundlapalli, Wiley A Schell, Kenneth Bulmahn, Thomas E Walton, Christopher W Woods, Catherine Coghill, Frank Gallegos, Matthew H Samore, Frederick R Adler
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003555 (2013)
Anthrax poses a community health risk due to accidental or intentional aerosol release. Reliable quantitative dose-response analyses are required to estimate the magnitude and timeline of potential consequences and the effect of public health interve
Externí odkaz:
https://doaj.org/article/ce8ecd5e3e8345b3aab79079c062f0a2
Autor:
Amber M Smith, Frederick R Adler, Ruy M Ribeiro, Ryan N Gutenkunst, Julie L McAuley, Jonathan A McCullers, Alan S Perelson
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003238 (2013)
Secondary bacterial infections are a leading cause of illness and death during epidemic and pandemic influenza. Experimental studies suggest a lethal synergism between influenza and certain bacteria, particularly Streptococcus pneumoniae, but the pre
Externí odkaz:
https://doaj.org/article/80bd0af2c13d47d994bd55b47d3c9a6a
Autor:
Theodore G Liou, Frederick R Adler, Ruth H Keogh, Yanping Li, Judy L Jensen, William Walsh, Kristyn Packer, Teresa Clark, Holly Carveth, Jun Chen, Shaunessy L Rogers, Christen Lane, James Moore, Anne Sturrock, Robert Paine, David R Cox, John R Hoidal
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42748 (2012)
Lung function, acute pulmonary exacerbations (APE), and weight are the best clinical predictors of survival in cystic fibrosis (CF); however, underlying mechanisms are incompletely understood. Biomarkers of current disease state predictive of future
Externí odkaz:
https://doaj.org/article/7843fedf4401419791f58102bfdfca2b
Autor:
Amber M Smith, Frederick R Adler, Julie L McAuley, Ryan N Gutenkunst, Ruy M Ribeiro, Jonathan A McCullers, Alan S Perelson
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 2, p e1001081 (2011)
Relatively little is known about the viral factors contributing to the lethality of the 1918 pandemic, although its unparalleled virulence was likely due in part to the newly discovered PB1-F2 protein. This protein, while unnecessary for replication,
Externí odkaz:
https://doaj.org/article/4b22962761f448a1bf1fbadf1a1cf4b9
Autor:
Theodore G. Liou, Natalia Argel, Fadi Asfour, Perry S. Brown, Barbara A. Chatfield, David R. Cox, Cori L. Daines, Dixie Durham, Jessica A. Francis, Barbara Glover, My Helms, Theresa Heynekamp, John R. Hoidal, Judy L. Jensen, Christiana Kartsonaki, Ruth Keogh, Carol M. Kopecky, Noah Lechtzin, Yanping Li, Jerimiah Lysinger, Osmara Molina, Craig Nakamura, Kristyn A. Packer, Robert Paine, III, Katie R. Poch, Alexandra L. Quittner, Peggy Radford, Abby J. Redway, Scott D. Sagel, Rhonda D. Szczesniak, Shawna Sprandel, Jennifer L. Taylor-Cousar, Jane B. Vroom, Ryan Yoshikawa, John P. Clancy, J. Stuart Elborn, Kenneth N. Olivier, Frederick R. Adler
Publikováno v:
iScience, Vol 27, Iss 3, Pp 108835- (2024)
Summary: Airway inflammation underlies cystic fibrosis (CF) pulmonary exacerbations. In a prospective multicenter study of randomly selected, clinically stable adolescents and adults, we assessed relationships between 24 inflammation-associated molec
Externí odkaz:
https://doaj.org/article/0b6e6acfca2f4e87b4dbc09bc0ef7656
Autor:
Kim Cuddington, Karen C Abbott, Frederick R Adler, Mehmet Aydeniz, Rene Dale, Louis J Gross, Alan Hastings, Elizabeth A Hobson, Vadim A Karatayev, Alexander Killion, Aasakiran Madamanchi, Michelle L Marraffini, Audrey L McCombs, Widodo Samyono, Shin-Han Shiu, Karen H Watanabe, Easton R White
Publikováno v:
BioScience. 73:364-375
New graduate students in biology programs may lack the quantitative skills necessary for their research and professional careers. The acquisition of these skills may be impeded by teaching and mentoring experiences that decrease rather than increase
Publikováno v:
Ecology Letters. 26:398-410