Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Frederick P. Arnold"'
Autor:
Craig L. Bennett, Somasish Dastidar, Frederick J. Arnold, Spencer U. McKinstry, Cameron Stockford, Brian D. Freibaum, Bryce L. Sopher, Meilin Wu, Glen Seidner, William Joiner, J. Paul Taylor, Ryan J. H. West, Albert R. La Spada
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-18 (2023)
Abstract Identifying genetic modifiers of familial amyotrophic lateral sclerosis (ALS) may reveal targets for therapeutic modulation with potential application to sporadic ALS. GGGGCC (G4C2) repeat expansions in the C9orf72 gene underlie the most com
Externí odkaz:
https://doaj.org/article/6f3ba7e74a9b45459c4b799036492c5d
Autor:
Frederick J. Arnold, Alexandra F. Putka, Urmimala Raychaudhuri, Solomon Hsu, Richard S. Bedlack, Craig L. Bennett, Albert R. La Spada
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5587 (2024)
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disorder. While there are five FDA-approved drugs for treating this disease, each has only modest benefits. To design new and more effective therapies for ALS, particularly for spora
Externí odkaz:
https://doaj.org/article/d20eaf2f4c424d2b8c67b0bff66a8ea7
Autor:
Ya Cui, Frederick J. Arnold, Fanglue Peng, Dan Wang, Jason Sheng Li, Sebastian Michels, Eric J. Wagner, Albert R. La Spada, Wei Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Alternative polyadenylation (APA) contributes to the post-transcriptional regulation of most human genes, yet the effects of APA are largely overlooked by conventional transcriptome-wide association studies (TWAS). Here, the authors conduct an APA-TW
Externí odkaz:
https://doaj.org/article/3b9acc93f1604e6d9cce16b07c9ad72d
Publikováno v:
The Journal of Physical Chemistry A. 107:2737-2742
Gradient-corrected density functional theory calculations have resulted in geometry-optimized structures for a series of six large dirhodium complexes that are important synthetic intermediates in the weak-link synthetic approach. Analysis of these c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84adb6340e7c28f0d338c8c93b91f362
https://doi.org/10.1021/jp022071l
https://doi.org/10.1021/jp022071l
Autor:
Frederick P. Arnold
Publikováno v:
Journal of Organometallic Chemistry. :647-655
Hybrid DFT/HF calculations were performed on five complexes (PH 3 ) 2 (H)PtSi(SH) 2 + , (PH 3 ) 2 (H)PtSi(SMe) 2 + , (PMe 3 ) 2 (H)PtSi(SMe) 2 + , (P i Pr 3 ) 2 (H)PtSi(SEt) 2 + , and (PCy 3 ) 2 (H)PtSi(SEt) 2 + , and analyzed using CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ebcc529242a0c871e95cfe4eade2162
https://doi.org/10.1016/s0022-328x(00)00737-3
https://doi.org/10.1016/s0022-328x(00)00737-3
Publikováno v:
Proceedings of the National Academy of Sciences. 96:3479-3485
Catalysis at organophilic silica-rich surfaces of zeolites and feldspars might generate replicating biopolymers from simple chemicals supplied by meteorites, volcanic gases, and other geological sources. Crystal–chemical modeling yielded packings f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb091fa271c06ea3f3c20615629a6e3b
https://doi.org/10.1073/pnas.96.7.3479
https://doi.org/10.1073/pnas.96.7.3479
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 109:333-336
The Diels-Alder reactivity of the keto vinylphosphonate 1 with furan, cyclopentadiene and E-1-acetoxy-1,3-butadiene was investigated with and without Lewis acid assistance. The acetyl group directed in each case. LUMO molecular orbital coefficients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::369fc95516d37bb2271e419c5df74c3a
https://doi.org/10.1080/10426509608046266
https://doi.org/10.1080/10426509608046266
Publikováno v:
Angewandte Chemie International Edition in English. 34:1887-1890
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b9b941c5cde0be4bd26ec2690572f3e
https://doi.org/10.1002/anie.199518871
https://doi.org/10.1002/anie.199518871
Publikováno v:
Organometallics. 13:5049-5053
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d52b2d19c9d7d606bd9bdf82f9ce562d
https://doi.org/10.1021/om00024a055
https://doi.org/10.1021/om00024a055