Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Frederick M Dirbas"'
Autor:
Taichi Isobe, Shigeo Hisamori, Daniel J Hogan, Maider Zabala, David G Hendrickson, Piero Dalerba, Shang Cai, Ferenc Scheeren, Angera H Kuo, Shaheen S Sikandar, Jessica S Lam, Dalong Qian, Frederick M Dirbas, George Somlo, Kaiqin Lao, Patrick O Brown, Michael F Clarke, Yohei Shimono
Publikováno v:
eLife, Vol 3 (2014)
MicroRNAs (miRNAs) are important regulators of stem and progenitor cell functions. We previously reported that miR-142 and miR-150 are upregulated in human breast cancer stem cells (BCSCs) as compared to the non-tumorigenic breast cancer cells. In th
Externí odkaz:
https://doaj.org/article/12df545b9b7f407281bc82e145ae3c9e
Autor:
Hongxiang Yu, Diana L Simons, Ilana Segall, Valeria Carcamo-Cavazos, Erich J Schwartz, Ning Yan, Neta S Zuckerman, Frederick M Dirbas, Denise L Johnson, Susan P Holmes, Peter P Lee
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51239 (2012)
Lymph node metastasis is a key event in the progression of breast cancer. Therefore it is important to understand the underlying mechanisms which facilitate regional lymph node metastatic progression.We performed gene expression profiling of purified
Externí odkaz:
https://doaj.org/article/e8f7d0b2e93147a99002eece96043cb1
Autor:
Hila Confino, Frederick M. Dirbas, Matan Goldshtein, Shay Yarkoni, Rinat Kalaora, Meital Hatan, Shani Puyesky, Yakir Levi, Lidor Malka, Matt Johnson, Selena Chaisson, Jedidiah M. Monson, Amir Avniel, Steve Lisi, David Greenberg, Ido Wolf
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background In-situ tumor ablation provides the immune system with the appropriate antigens to induce anti-tumor immunity. Here, we present an innovative technique for generating anti-tumor immunity by delivering exogenous ultra-high concentr
Externí odkaz:
https://doaj.org/article/7bbe5e96ca9645cd8b067277ecdfdbbb
Autor:
Hila Confino, Yogev Sela, Yana Epshtein, Lidor Malka, Matan Goldshtein, Selena Chaisson, Steve Lisi, Amir Avniel, Jedidiah Mercer Monson, Frederick M. Dirbas
Publikováno v:
Cells, Vol 12, Iss 20, p 2439 (2023)
Background: Immune checkpoint inhibitors have transformed clinical oncology. However, their use is limited as response is observed in only ~20–50% of patients. Previously, we demonstrated that treating CT26 tumor-bearing mice with ultra-high-concen
Externí odkaz:
https://doaj.org/article/07cb9dad2a0b4bbeae273d47cdda664d
Autor:
Shaheen S. Sikandar, Angera H. Kuo, Tomer Kalisky, Shang Cai, Maider Zabala, Robert W. Hsieh, Neethan A. Lobo, Ferenc A. Scheeren, Sopheak Sim, Dalong Qian, Frederick M. Dirbas, George Somlo, Stephen R. Quake, Michael F. Clarke
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The contribution of EMT in mammary gland homeostasis and human breast cancer is still unclear. Here, using in vivo lineage tracing and breast cancer PDXs the authors demonstrate that the repopulating capacity in normal mammary epithelial cells and tu
Externí odkaz:
https://doaj.org/article/f0f50f3b3e2d42029e585ebb81c7168c
Autor:
Peter P. Lee, James Waisman, John Yim, Frederick M. Dirbas, Vernon C. Maino, Maria A. Suni, Carrie Wang, Andrew Y. Chang, Xuyang Lu, Diana L. Simons, Andrea K. Miyahira, Lei Wang
IL6 is a pleiotropic cytokine with both pro- and anti-inflammatory properties, which acts directly on cancer cells to promote their survival and proliferation. Elevated serum IL6 levels negatively correlate with survival of cancer patients, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0e185f34ece49208f33865e7c75eb0
https://doi.org/10.1158/0008-5472.c.6509643.v1
https://doi.org/10.1158/0008-5472.c.6509643.v1
Autor:
Frederick M. Dirbas, Gabriela Ruchelli, Sean Mackey, Ian Carroll, Debra Clay, Heather Hilmoe, Tina Hernandez Boussard, Yasamin Sharifzadeh, Peter P. Schmidt, Jennifer M. Hah, Jodie A. Trafton, James I. Huddleston, Rebecca McCue, Stuart B. Goodman, Joseph B. Shrager, William J. Maloney, Catherine Curtin, John G. Costouros
Publikováno v:
Journal of Pain Research
Jennifer M Hah,1 Heather Hilmoe,2 Peter Schmidt,2 Rebecca McCue,2 Jodie Trafton,3,4 Debra Clay,2 Yasamin Sharifzadeh,2 Gabriela Ruchelli,2 Tina Hernandez Boussard,5 Stuart Goodman,6 James Huddleston,7 William J Maloney,7 Frederick M Dirbas,8 Joseph S
Autor:
Margaret M. Kozak, Frederick M. Dirbas, Emily Walck, Rie von Eyben, Clare E. Jacobson, Kathleen C. Horst, Paulina M. Gutkin
Publikováno v:
Clinical Breast Cancer. 20:431-438
Background Optimal surgical management of limited axillary nodal disease following neoadjuvant chemotherapy (NAC) for breast cancer is evolving. Concerns exist with respect to leaving residual disease in the axilla when omitting axillary lymph node d
Autor:
Kristen N. Ganjoo, Kathleen C. Horst, Rahim Nazerali, Paulina M. Gutkin, Marti Lohman, Rie von Eyben, Frederick M. Dirbas, Gregory W. Charville
Publikováno v:
American Journal of Clinical Oncology. 43:820-825
Angiosarcoma of the breast is rare and has a poor prognosis. We reviewed our institution's experience with this disease to characterize presentation, identify management patterns, and report outcomes.Fifty-eight patients with nonmetastatic angiosarco
Autor:
Erin Hawley, Gordon K. Lee, Rie von Eyben, Paulina M. Gutkin, Frederick M. Dirbas, Kathleen C. Horst, Jie Jane Chen
Publikováno v:
Annals of Surgical Oncology. 28:1669-1679
The aim of this study was to determine the complications, incidence, and predictors of implant-based reconstruction failure (RF) among patients treated with mastectomy for breast cancer. We retrospectively reviewed 108 patients who underwent mastecto