Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Frederick J. Lakner"'
Autor:
Mathew P.D. Mahindaratne, Brian A. Quiñones, Antonio Recio III, Erik A. Rodriguez, Frederick J. Lakner, George R. Negrete
Publikováno v:
ARKIVOC, Vol 2005, Iss 6, Pp 321-328 (2005)
Externí odkaz:
https://doaj.org/article/dc27ae2cd5bc4b5f959e0e11683de637
Autor:
Ande Bao, Maritza V. Quintero, George R. Negrete, William T. Phillips, Beth A. Goins, Adelphe M. Mfuh, Mathew P. D. Mahindaratne, Frederick J. Lakner
Publikováno v:
Langmuir. 27:4447-4455
A novel asparagine-derived lipid analogue (ALA(11,17)) bearing a tetrahydropyrimidinone headgroup and two fatty chains (11 and 17 indicate the lengths of linear alkyl groups) was synthesized in high yield and purity. The thin film hydration of formul
Autor:
Boris V. Rogovoy, Alexander V. Ivachtchenko, Matthew A. Parker, Frederick J. Lakner, Alexander Viktorovich Khvat
Publikováno v:
Synthesis. 2009:1987-1990
Imidazolines substituted at the 1- and either the 4-, or 5-position with phenyl and at the 2-position with alkyl or phenyl have been prepared in racemic form. They appear to be fairly stable compounds and potentially useful as scaffolds in medicinal
Autor:
Frederick J. Lakner, Brian A. Quiñones, Eric A. Rodriguez, Antonio Recio, Mathew P. D. Mahindaratne, George R. Negrete
Publikováno v:
Tetrahedron. 61:9495-9501
Results are reported on the salt, concentration, and temperature effects in an aqueous, auxiliary-mediated asymmetric Diels–Alder cycloaddition. The auxiliaries were prepared under basic aqueous conditions from asparagine and trimethylacetaldehyde,
Autor:
Brian A. Quiñones, Frederick J. Lakner, Eric A. Rodriguez, Antonio Recio, Mathew P. D. Mahindaratne, George R. Negrete
Publikováno v:
ARKIVOC, Vol 2005, Iss 6, Pp 321-328 (2005)
A fully-telescoped, aqueous, auxiliary-mediated Diels-Alder cycloaddition in moderate selectivity is reported. The auxiliary is prepared from L-asparagine and trimethylacetaldehyde, and coupled without isolation to the acryloyl substrate. Direct addi
Autor:
Kathy G. Jahangiri, Michael K. Dalton, Haiji Xia, Jeffrey R. Hammaker, Azra Pervin, Alexandre V. Ivachtchenko, Frederick J. Lakner, Alexander Viktorovich Khvat, Alexander S. Kiselyov
Publikováno v:
Tetrahedron Letters. 46:5325-5328
Novel mesoionic heterocyclic structures 8 have been obtained via the internal cyclization of thio- and amino-acid derivatives of 6-azauracil 7b–d . These compounds undergo ring-opening reactions with amines to yield the respective 6-azauracil amide
Publikováno v:
Organic Letters. 15:2598-2600
A new route to the ergoline skeleton has been developed that does not require prior functionalization of the indole 4-position. The indole nucleus is introduced late in the synthesis to allow for eventual efficient introduction of substituents in thi
Autor:
Coleman Gross, Bishwajit Nag, Satyanarayana Medicherla, Lesley B Pickford, Debendranath Dey, Frederick J. Lakner, Maya S. Gowri, Somesh Sharma, Partha Neogi, Jin Cheng
Publikováno v:
Bioorganic & Medicinal Chemistry. 11:4059-4067
A number of 2,4-thiazolidinedione derivatives of -phenyl substituted cinnamic acid were synthesized and studied for their PPAR agonist activity. The E-isomer of cinnamic acid, 11, showed moderate PPAR transactivation. The corresponding Z-isomer, 23,
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 9:107-111
The stereochemistry of the chloroperoxidase-catalyzed epoxidation of indene has been elucidated. In aqueous solution the intial epoxide product is not stable and opens to form the cis-trans diols. When the reaction was carried out in the absence of w
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 5:95-101
Recent experiments from several laboratories have shown that chloroperoxidase is able to catalyze a broad spectrum of stereoselective hydroxylation, sulfoxidation and epoxidation reactions. Our laboratory has investigated the substrate specificity of