Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Frederick J Kohlhapp"'
Autor:
Marco Rossi, Salvatore M. Aspromonte, Frederick J. Kohlhapp, Jenna H. Newman, Alex Lemenze, Russell J. Pepe, Samuel M. DeFina, Nora L. Herzog, Robert Donnelly, Timothy M. Kuzel, Jochen Reiser, Jose A. Guevara-Patino, Andrew Zloza
Publikováno v:
Diagnostics, Vol 12, Iss 4, p 958 (2022)
Through a multitude of studies, the gut microbiota has been recognized as a significant influencer of both homeostasis and pathophysiology. Certain microbial taxa can even affect treatments such as cancer immunotherapies, including the immune checkpo
Externí odkaz:
https://doaj.org/article/fb4d6e6cb67047918d92eaad3c631ea6
Autor:
Tamar Uziel, William N. Pappano, Cherrie Donawho, Joel D. Leverson, Keith M. Hamel, Ahmed Hamed Salem, Anahita Bhathena, Mark Merchant, Aparna Raval, Deepak Sampath, Christine J. Orr, Yijin Li, An D. Do, Valerie A. Robinson, Jacob J. Riehm, Nimita Dave, Yan Shi, Elisabeth A. Lasater, Rui Wang, Paul A. Ellis, Ryan Duggan, Rebecca Mathew, Dipica Haribhai, Frederick J. Kohlhapp
Supplementary Figures S1-S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704a1bb80d5836350d691acabb9a1130
https://doi.org/10.1158/2159-8290.22536893
https://doi.org/10.1158/2159-8290.22536893
Autor:
Tamar Uziel, William N. Pappano, Cherrie Donawho, Joel D. Leverson, Keith M. Hamel, Ahmed Hamed Salem, Anahita Bhathena, Mark Merchant, Aparna Raval, Deepak Sampath, Christine J. Orr, Yijin Li, An D. Do, Valerie A. Robinson, Jacob J. Riehm, Nimita Dave, Yan Shi, Elisabeth A. Lasater, Rui Wang, Paul A. Ellis, Ryan Duggan, Rebecca Mathew, Dipica Haribhai, Frederick J. Kohlhapp
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4de11efc8dd83fcbfcc50137f10a1b
https://doi.org/10.1158/2159-8290.22536896
https://doi.org/10.1158/2159-8290.22536896
Autor:
Tamar Uziel, William N. Pappano, Cherrie Donawho, Joel D. Leverson, Keith M. Hamel, Ahmed Hamed Salem, Anahita Bhathena, Mark Merchant, Aparna Raval, Deepak Sampath, Christine J. Orr, Yijin Li, An D. Do, Valerie A. Robinson, Jacob J. Riehm, Nimita Dave, Yan Shi, Elisabeth A. Lasater, Rui Wang, Paul A. Ellis, Ryan Duggan, Rebecca Mathew, Dipica Haribhai, Frederick J. Kohlhapp
The antiapoptotic protein BCL2 plays critical roles in regulating lymphocyte development and immune responses, and has also been implicated in tumorigenesis and tumor survival. However, it is unknown whether BCL2 is critical for antitumor immune resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0751600d98b83debcbf68ebf0f510515
https://doi.org/10.1158/2159-8290.c.6548264.v1
https://doi.org/10.1158/2159-8290.c.6548264.v1
Autor:
Frederick J. Kohlhapp, Erica J. Huelsmann, Andrew T. Lacek, Jason M. Schenkel, Jevgenijs Lusciks, Joseph R. Broucek, Josef W. Goldufsky, Tasha Hughes, Janet P. Zayas, Hubert Dolubizno, Ryan T. Sowell, Regina Kühner, Sarah Burd, John C. Kubasiak, Arman Nabatiyan, Sh’Rae Marshall, Praveen K. Bommareddy, Shengguo Li, Jenna H. Newman, Claude E. Monken, Sasha H. Shafikhani, Amanda L. Marzo, Jose A. Guevara-Patino, Ahmed Lasfar, Paul G. Thomas, Edmund C. Lattime, Howard L. Kaufman, Andrew Zloza
Publikováno v:
Cell Reports, Vol 17, Iss 4, Pp 957-965 (2016)
In light of increased cancer prevalence and cancer-specific deaths in patients with infections, we investigated whether infections alter anti-tumor immune responses. We report that acute influenza infection of the lung promotes distal melanoma growth
Externí odkaz:
https://doaj.org/article/21c3de3968b44525b8ba15963e57feea
Autor:
Frederick J. Kohlhapp, Jeremy A. O’Sullivan, Tamson V. Moore, Andrew Zloza, José A. Guevara-Patiño
Publikováno v:
Mol Immunol
CD8 T cells play a critical role in immunity against intracellular pathogens and cancer. A primary objective of T cell-based vaccine strategies is the induction of durable and effective immune responses. Achieving this goal involves more than simply
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bfda013de95e8285ce0bce7acacad2
https://europepmc.org/articles/PMC9992161/
https://europepmc.org/articles/PMC9992161/
Autor:
Sachin R. Jhawar, Aditya Thandoni, Praveen K. Bommareddy, Suemair Hassan, Frederick J. Kohlhapp, Sharad Goyal, Jason M. Schenkel, Ann W. Silk, Andrew Zloza
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
There has long been interest in innovating an approach by which tumor cells can be selectively and specifically targeted and destroyed. The discovery of viruses that lyse tumor cells, termed oncolytic viruses (OVs), has led to a revolution in the tre
Externí odkaz:
https://doaj.org/article/5607494a07a847aabe0433213e938815
Autor:
Ahmed Salem, Yan Shi, Aparna Raval, Mark Merchant, Tamar Uziel, Frederick J. Kohlhapp, Jacob J Riehm, Deepak Sampath, Elisabeth A. Lasater, Dipica Haribhai, Joel D. Leverson, Rebecca Mathew, Valerie A. Robinson, William N. Pappano, Christine Orr, Yijin Li, Anahita Bhathena, Keith M. Hamel, Nimita Dave, An D. Do, Cherrie K. Donawho, Paul A. Ellis, Ryan Duggan, Rui Wang
Publikováno v:
Cancer Discovery. 11:68-79
The antiapoptotic protein BCL2 plays critical roles in regulating lymphocyte development and immune responses, and has also been implicated in tumorigenesis and tumor survival. However, it is unknown whether BCL2 is critical for antitumor immune resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f58391c3ee015fd579955202af8160b
https://doi.org/10.1158/2159-8290.cd-19-0759
https://doi.org/10.1158/2159-8290.cd-19-0759
Autor:
Joseph R. Broucek, Eileena F. Giurini, Nora L. Herzog, Lisa K. Denzin, Gabriel Guevara-Aleman, C. Brent Chesson, Ricardo Estupinian, Marco Rossi, Mary J. Fidler, Raquel E. Redondo, Jai S. Rudra, Joyce Paras, Jochen Reiser, Amanda L. Marzo, Jyoti Malhotra, Shang Jui Wang, Emily S. Ruiz, Stuti Buddhadev, Howard L. Kaufman, Saeed Tarabichi, Sachin R. Jhawar, Frederick J. Kohlhapp, Daniel J. Medina, Mones M. Aboelatta, David Rotter, Shengguo Li, Leonard Y. Lee, Vineet Gupta, John Langenfeld, Ann W. Silk, Russell J. Pepe, Kajal Gupta, Timothy M. Kuzel, Jason M. Schenkel, Derek B. Sant'Angelo, Abdulkareem Abed, Jenna H. Newman, Michael J. Lee, Praveen K. Bommareddy, Salvatore M. Aspromonte, Ahmed Lasfar, Eric A. Singer, Michael P. Kane, Christina Nowicki, Arnold B. Rabson, Andrew Zloza, Paul G. Thomas, Josef W. Goldufsky
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Immunotherapy has revolutionized cancer treatment, yielding unprecedented long-term responses and survival. However, a significant proportion of patients remain refractory, which correlates with the absence of immune-infiltrated (“hot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab3df47d5bd7978884f383d0b95e201
https://doi.org/10.1073/pnas.1904022116
https://doi.org/10.1073/pnas.1904022116
Autor:
Alexey Y. Koyfman, Frederick J. Kohlhapp, Joshua D. Snook, Jai S. Rudra, Charles B. Chesson, Andrew Zloza, Rajagopal Appavu
Publikováno v:
ACS biomaterials scienceengineering. 1(7)
d-Amino acid analogs of peptides and proteins are attractive for applications in biotechnology and medicine due to their reduced proteolytic sensitivity. Here, we report that self-assembling peptide nanofibers composed of d-amino acids act as immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810d7a0cc8a6d9d21dd64da5bc0d6d74
https://pubmed.ncbi.nlm.nih.gov/33434976
https://pubmed.ncbi.nlm.nih.gov/33434976