Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Frederick G. Vogt"'
Publikováno v:
Journal of Pharmaceutical Sciences. 103:2937-2949
Dry powder inhalation aerosols of antibiotic drugs (a first-line aminoglycoside, tobramycin, and a first-line macrolide, azithromycin) and a sugar alcohol mucolytic agent (mannitol) as co-spray dried (co-SD) particles at various molar ratios of drug:
Autor:
Lianming Wu, R. Graham Cooks, Frederick G. Vogt, Christina R. Ferreira, Esteban R. Bornancini
Publikováno v:
Analytical Letters. 47:91-101
Fiducial markers are necessary for the accurate overlay of images obtained by different methods from small areas of a sample. Thus far, fiducial markers have been used for biological sample analysis by mass spectrometry imaging. In this work, spatial
Publikováno v:
Crystal Growth & Design. 13:5353-5367
Two polymorphic forms of ethyl 3-{3-[((2R)-3-{[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino}-2-hydroxypropyl)oxy]-4,5-difluorophenyl} propanoate hydrochloride, an investigational pharmaceutical compound, are characterized using spectroscopic
Autor:
Mark Strohmeier, Frederick G. Vogt
Publikováno v:
Molecular Pharmaceutics. 10:4216-4228
Chemical imaging using confocal Raman microscopy is a useful analytical tool in drug development because of its ability to spatially image active ingredients and excipients in dosage forms and relate their distribution to product performance. While R
Autor:
Joseph B. Zwischenberger, Frederick G. Vogt, Xiaojian Li, Eun-Seok Park, Don Hayes, Heidi M. Mansour, Chun-Woong Park
Publikováno v:
International Journal of Pharmaceutics. 455:374-392
Respirable microparticles/nanoparticles of the antibiotics vancomycin (VCM) and clarithromycin (CLM) were successfully designed and developed by novel organic solution advanced spray drying from methanol solution. Formulation optimization was achieve
Publikováno v:
Journal of Pharmaceutical Sciences. 102:3705-3716
A novel crystalline form of the boron-containing antibacterial drug (S)-3-(aminomethyl)-7-(3-hydroxypropoxy)benzo[c] [1,2]oxaborol-1(3H)-ol hydrochloride is studied by solid-state nuclear magnetic resonance (SSNMR) and single-crystal X-ray diffractio
Publikováno v:
Molecular Pharmaceutics. 10:3433-3446
(17)O solid-state NMR (SSNMR) can provide insight into hydrogen bonding interactions in pharmaceutical polymorphs, cocrystals, and amorphous dispersions. When combined with straightforward (17)O synthetic labeling, the use of (17)O SSNMR allows for d
Autor:
Dinu Iuga, Frederick G. Vogt, Andrew J. Edwards, Tran N. Pham, Andrew S. Tatton, Steven P. Brown
Publikováno v:
Molecular Pharmaceutics. 10:999-1007
Cocrystals and amorphous solid dispersions have generated interest in the pharmaceutical industry as an alternative to more established solid delivery forms. The identification of intermolecular hydrogen bonding interactions in a nicotinamide palmiti
Autor:
Mark Strohmeier, Frederick G. Vogt
Publikováno v:
Molecular Pharmaceutics. 9:3357-3374
The solubility of drug molecules can often be improved through preparation and delivery of cyclodextrin (CD) inclusion complexes. These drug-oligosaccharide complexes can be prepared in solution and converted to the solid state via methods such as ly
Autor:
Robert A. Carlton, Thomas E. Needham, Clinton O. Chichester, Frederick G. Vogt, Jagdishwar R. Patel
Publikováno v:
International Journal of Pharmaceutics. 436:685-706
Cocrystals of tenoxicam, a non-steroidal anti-inflammatory drug, are screened, prepared, and characterized in this study. Nine tenoxicam cocrystals were identified using solvent-drop grinding (SDG) techniques. Structural characterization was performe