Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Frederick G Barker"'
Autor:
Jules P. J. Douwes, Kimberley S. Koetsier, Victor S. van Dam, Scott R. Plotkin, Frederick G. Barker, D. Bradley Welling, Jeroen C. Jansen, Erik F. Hensen, Helen A. Shih
Publikováno v:
Current Oncology, Vol 30, Iss 3, Pp 3473-3483 (2023)
(1) Background: This study aimed to evaluate the efficacy and treatment-related toxicity of proton radiotherapy (PRT) for vestibular schwannoma (VS) in patients with neurofibromatosis type 2-related schwannomatosis (NF2). (2) Methods: Consecutive NF2
Externí odkaz:
https://doaj.org/article/b4d64cf4638e4147b0e51ad30998698c
Autor:
Priscilla K. Brastianos, Erin L. Twohy, Elizabeth R. Gerstner, Timothy J. Kaufmann, A. John Iafrate, Jochen Lennerz, Suriya Jeyapalan, David E. Piccioni, Varun Monga, Camilo E. Fadul, David Schiff, Jennie W. Taylor, Sajeel A. Chowdhary, Chetan Bettegowda, George Ansstas, Macarena De La Fuente, Mark D. Anderson, Nicole Shonka, Denise Damek, Jose Carrillo, Lara J. Kunschner-Ronan, Rekha Chaudhary, Kurt A. Jaeckle, Francis M. Senecal, Thomas Kaley, Tara Morrison, Alissa A. Thomas, Mary R. Welch, Fabio Iwamoto, David Cachia, Adam L. Cohen, Shivangi Vora, Michael Knopp, Ian F. Dunn, Priya Kumthekar, Jann Sarkaria, Susan Geyer, Xiomara W. Carrero, Maria Martinez-Lage, Daniel P. Cahill, Paul D. Brown, Caterina Giannini, Sandro Santagata, Frederick G. Barker, Evanthia Galanis
Publikováno v:
Journal of Clinical Oncology. 41:618-628
PURPOSE Patients with progressive or recurrent meningiomas have limited systemic therapy options. Focal adhesion kinase (FAK) inhibition has a synthetic lethal relationship with NF2 loss. Given the predominance of NF2 mutations in meningiomas, we eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13d92dd4797c6a215de625e0d33d141d
https://doi.org/10.1200/jco.21.02371
https://doi.org/10.1200/jco.21.02371
Autor:
Greenberg, Ana B W, Mekbib, Kedous Y, Mehta, Neel H, Kiziltug, Emre, Duy, Phan Q, Smith, Hannah R, Junkkari, Antti, Leinonen, Ville, Hyman, Bradley T, Chan, Diane, Jr, William T Curry, Arnold, Steven E, II, Frederick G Barker, Frosch, Matthew P, Kahle, Kristopher T
Publikováno v:
Cerebral Cortex; Feb2024, Vol. 34 Issue 2, p1-13, 13p
Autor:
William C. Hahn, Gad Getz, David N. Louis, José Baselga, Tracy T. Batchelor, Rameen Beroukhim, Eric S. Lander, Stacey Gabriel, Levi Garraway, Matthew Meyerson, Anat Stemmer-Rachamimov, Eric P. Winer, Nancy U. Lin, Michael S. Rabin, Carrie Sougnez, Sabina Signoretti, Toni K. Choueiri, Mai P. Hoang, Bruce E. Johnson, Aaron R. Thorner, Paul Van Hummelen, Corey M. Gill, Frederick G. Barker, Mara Rosenberg, Aaron Chevalier, Aaron McKenna, Sung-Hye Park, Sun Ha Paek, Ian F. Dunn, William T. Curry, Elena Martinez-Saez, Joan Seoane, Josep Tabernero, Keith L. Ligon, Kristian Cibulskis, Peleg M. Horowitz, Michael S. Lawrence, Eliezer M. Van Allen, Robert T. Jones, Amaro Taylor-Weiner, Daniel P. Cahill, Sandro Santagata, Scott L. Carter, Priscilla K. Brastianos
Summary of clinically informative (TARGET) genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855c0245b2a1e6713daa8b18bc320c76
https://doi.org/10.1158/2159-8290.22529903.v1
https://doi.org/10.1158/2159-8290.22529903.v1
Autor:
William C. Hahn, Gad Getz, David N. Louis, José Baselga, Tracy T. Batchelor, Rameen Beroukhim, Eric S. Lander, Stacey Gabriel, Levi Garraway, Matthew Meyerson, Anat Stemmer-Rachamimov, Eric P. Winer, Nancy U. Lin, Michael S. Rabin, Carrie Sougnez, Sabina Signoretti, Toni K. Choueiri, Mai P. Hoang, Bruce E. Johnson, Aaron R. Thorner, Paul Van Hummelen, Corey M. Gill, Frederick G. Barker, Mara Rosenberg, Aaron Chevalier, Aaron McKenna, Sung-Hye Park, Sun Ha Paek, Ian F. Dunn, William T. Curry, Elena Martinez-Saez, Joan Seoane, Josep Tabernero, Keith L. Ligon, Kristian Cibulskis, Peleg M. Horowitz, Michael S. Lawrence, Eliezer M. Van Allen, Robert T. Jones, Amaro Taylor-Weiner, Daniel P. Cahill, Sandro Santagata, Scott L. Carter, Priscilla K. Brastianos
Supplementary Methods, Figures S1 - S20. Figure S1. Branched evolution leads to tissue-sampling bias in primary tumor samples. Figure S2. Results of ABSOLUTE on samples from patient 418. Figure S3. 2D Bayesian clustering analysis of point-mutation CC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0331e34689955dc5aa0e3ac37c35925f
https://doi.org/10.1158/2159-8290.22529912.v1
https://doi.org/10.1158/2159-8290.22529912.v1
Autor:
William C. Hahn, Gad Getz, David N. Louis, José Baselga, Tracy T. Batchelor, Rameen Beroukhim, Eric S. Lander, Stacey Gabriel, Levi Garraway, Matthew Meyerson, Anat Stemmer-Rachamimov, Eric P. Winer, Nancy U. Lin, Michael S. Rabin, Carrie Sougnez, Sabina Signoretti, Toni K. Choueiri, Mai P. Hoang, Bruce E. Johnson, Aaron R. Thorner, Paul Van Hummelen, Corey M. Gill, Frederick G. Barker, Mara Rosenberg, Aaron Chevalier, Aaron McKenna, Sung-Hye Park, Sun Ha Paek, Ian F. Dunn, William T. Curry, Elena Martinez-Saez, Joan Seoane, Josep Tabernero, Keith L. Ligon, Kristian Cibulskis, Peleg M. Horowitz, Michael S. Lawrence, Eliezer M. Van Allen, Robert T. Jones, Amaro Taylor-Weiner, Daniel P. Cahill, Sandro Santagata, Scott L. Carter, Priscilla K. Brastianos
Supplementary File 1. Power for detection of somatic point mutations in coding exons of TARGET genes. The description for the plots in Supplementary File 1 can be found in the Legend of Supplementary Figure S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32879f7c6c123ed86a2c2dfd03a02d5a
https://doi.org/10.1158/2159-8290.22529933.v1
https://doi.org/10.1158/2159-8290.22529933.v1
Autor:
William C. Hahn, Gad Getz, David N. Louis, José Baselga, Tracy T. Batchelor, Rameen Beroukhim, Eric S. Lander, Stacey Gabriel, Levi Garraway, Matthew Meyerson, Anat Stemmer-Rachamimov, Eric P. Winer, Nancy U. Lin, Michael S. Rabin, Carrie Sougnez, Sabina Signoretti, Toni K. Choueiri, Mai P. Hoang, Bruce E. Johnson, Aaron R. Thorner, Paul Van Hummelen, Corey M. Gill, Frederick G. Barker, Mara Rosenberg, Aaron Chevalier, Aaron McKenna, Sung-Hye Park, Sun Ha Paek, Ian F. Dunn, William T. Curry, Elena Martinez-Saez, Joan Seoane, Josep Tabernero, Keith L. Ligon, Kristian Cibulskis, Peleg M. Horowitz, Michael S. Lawrence, Eliezer M. Van Allen, Robert T. Jones, Amaro Taylor-Weiner, Daniel P. Cahill, Sandro Santagata, Scott L. Carter, Priscilla K. Brastianos
Supplementary File 3. Detailed plots of the data used for phylogenetic inference in each case. The description for the plots in Supplementary File 3 can be found in the Legend of Supplementary Figure S13-S17.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10df6109c230fc926c0731a4aceb31f5
https://doi.org/10.1158/2159-8290.22529918.v1
https://doi.org/10.1158/2159-8290.22529918.v1
Autor:
William C. Hahn, Gad Getz, David N. Louis, José Baselga, Tracy T. Batchelor, Rameen Beroukhim, Eric S. Lander, Stacey Gabriel, Levi Garraway, Matthew Meyerson, Anat Stemmer-Rachamimov, Eric P. Winer, Nancy U. Lin, Michael S. Rabin, Carrie Sougnez, Sabina Signoretti, Toni K. Choueiri, Mai P. Hoang, Bruce E. Johnson, Aaron R. Thorner, Paul Van Hummelen, Corey M. Gill, Frederick G. Barker, Mara Rosenberg, Aaron Chevalier, Aaron McKenna, Sung-Hye Park, Sun Ha Paek, Ian F. Dunn, William T. Curry, Elena Martinez-Saez, Joan Seoane, Josep Tabernero, Keith L. Ligon, Kristian Cibulskis, Peleg M. Horowitz, Michael S. Lawrence, Eliezer M. Van Allen, Robert T. Jones, Amaro Taylor-Weiner, Daniel P. Cahill, Sandro Santagata, Scott L. Carter, Priscilla K. Brastianos
Supplementary File 2. Detailed plots of SCNA calls in TARGET genes. The description for the plots in Supplementary File 2 can be found in the Legend of Supplementary Figure S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0009411fb48ee874f34b90301ff3d7
https://doi.org/10.1158/2159-8290.22529927
https://doi.org/10.1158/2159-8290.22529927
Autor:
Priscilla K, Brastianos, Erin L, Twohy, Elizabeth R, Gerstner, Timothy J, Kaufmann, A John, Iafrate, Jochen, Lennerz, Suriya, Jeyapalan, David E, Piccioni, Varun, Monga, Camilo E, Fadul, David, Schiff, Jennie W, Taylor, Sajeel A, Chowdhary, Chetan, Bettegowda, George, Ansstas, Macarena, De La Fuente, Mark D, Anderson, Nicole, Shonka, Denise, Damek, Jose, Carrillo, Lara J, Kunschner-Ronan, Rekha, Chaudhary, Kurt A, Jaeckle, Francis M, Senecal, Thomas, Kaley, Tara, Morrison, Alissa A, Thomas, Mary R, Welch, Fabio, Iwamoto, David, Cachia, Adam L, Cohen, Shivangi, Vora, Michael, Knopp, Ian F, Dunn, Priya, Kumthekar, Jann, Sarkaria, Susan, Geyer, Xiomara W, Carrero, Maria, Martinez-Lage, Daniel P, Cahill, Paul D, Brown, Caterina, Giannini, Sandro, Santagata, Frederick G, Barker, Evanthia, Galanis
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
Patients with progressive or recurrent meningiomas have limited systemic therapy options. Focal adhesion kinase (FAK) inhibition has a synthetic lethal relationship withEligible patients whose tumors screened positively forOf 322 patients screened fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15320c49eedc56725b5f7b9cc65c4517
https://pubmed.ncbi.nlm.nih.gov/36288512
https://pubmed.ncbi.nlm.nih.gov/36288512
Autor:
Nazanin Ijad, Katie L Waller, Naema Nayyar, Juliana M Larson, Joshua Spear, Daniel Cahill, Frederick G Barker, Evanthia Galanis, Jann Sarkaria, Hiroaki Wakimoto, Rachael Vaubel, Priscilla Brastianos
Publikováno v:
Neuro-Oncology. 24:vii230-vii230
BACKGROUND Adequate treatment options are limited for patients with meningiomas once they have exhausted surgery and radiation. As our molecular understanding of meningiomas and their progression has improved, CDK, FAK, and RAF/MEK pathways have emer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4547a047ec9fe74a1ed60a0712bff60
https://doi.org/10.1093/neuonc/noac209.887
https://doi.org/10.1093/neuonc/noac209.887