Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Frederick Fasslrinner"'
Autor:
Alberto Farina, Federico Moro, Frederick Fasslrinner, Annahita Sedghi, Miluska Bromley, Timo Siepmann
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 4, Pp n/a-n/a (2021)
Abstract We aimed to evaluate the quality of clinical evidence that substantiated approval of cancer medicines by the European Medicines Agency (EMA) in the last decade. We performed a systematic review and data synthesis of EMA documents in agreemen
Externí odkaz:
https://doaj.org/article/5715cc312b3140ea947895803ac37af7
Autor:
Claudia Arndt, Ralf Bergmann, Franziska Striese, Keresztély Merkel, Domokos Máthé, Liliana R. Loureiro, Nicola Mitwasi, Alexandra Kegler, Frederick Fasslrinner, Karla Elizabeth González Soto, Christin Neuber, Nicole Berndt, Noemi Kovács, David Szöllősi, Nikolett Hegedűs, Gyula Tóth, Jan-Philipp Emmermann, Kuzhuvelil B. Harikumar, Tibor Kovacs, Michael Bachmann, Anja Feldmann
Publikováno v:
Cancers, Vol 14, Iss 8, p 1996 (2022)
Due to its overexpression on the surface of prostate cancer (PCa) cells, the prostate stem cell antigen (PSCA) is a potential target for PCa diagnosis and therapy. Here we describe the development and functional characterization of a novel IgG4-based
Externí odkaz:
https://doaj.org/article/da681e363d144efb9ab0260acdccdda2
Autor:
Nicola Mitwasi, Claudia Arndt, Liliana R. Loureiro, Alexandra Kegler, Frederick Fasslrinner, Nicole Berndt, Ralf Bergmann, Vaclav Hořejší, Claudia Rössig, Michael Bachmann, Anja Feldmann
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4920 (2022)
Chimeric antigen receptor (CAR)-expressing T-cells are without a doubt a breakthrough therapy for hematological malignancies. Despite their success, clinical experience has revealed several challenges, which include relapse after targeting single ant
Externí odkaz:
https://doaj.org/article/e3db933984b54b74941f83245e288cf4
Autor:
Claudia Arndt, Liliana R. Loureiro, Anja Feldmann, Justyna Jureczek, Ralf Bergmann, Domokos Máthé, Nikolett Hegedüs, Nicole Berndt, Stefanie Koristka, Nicola Mitwasi, Frederick Fasslrinner, Chris Lamprecht, Alexandra Kegler, Anja Hoffmann, Tabea Bartsch, Ayşe Sedef Köseer, Gary Egan, Marc Schmitz, Vaclav Hořejší, Mechthild Krause, Anna Dubrovska, Michael Bachmann
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Induction or selection of radioresistant cancer (stem) cells following standard radiotherapy is presumably one of the major causes for recurrence of metastatic disease. One possibility to prevent tumor relapse is the application of targeted immunothe
Externí odkaz:
https://doaj.org/article/e9bde3c3ab474cab96ef8a34e0e398cf
Autor:
Enrico Kittel-Boselli, Karla Elizabeth González Soto, Liliana Rodrigues Loureiro, Anja Hoffmann, Ralf Bergmann, Claudia Arndt, Stefanie Koristka, Nicola Mitwasi, Alexandra Kegler, Tabea Bartsch, Nicole Berndt, Heidi Altmann, Frederick Fasslrinner, Martin Bornhäuser, Michael Philipp Bachmann, Anja Feldmann
Publikováno v:
Cancers, Vol 13, Iss 19, p 4785 (2021)
Clinical translation of novel immunotherapeutic strategies such as chimeric antigen receptor (CAR) T-cells in acute myeloid leukemia (AML) is still at an early stage. Major challenges include immune escape and disease relapse demanding for further im
Externí odkaz:
https://doaj.org/article/28296890c8614cac9e4dfb47de97b556
Autor:
Claudia Arndt, Frederick Fasslrinner, Liliana R. Loureiro, Stefanie Koristka, Anja Feldmann, Michael Bachmann
Publikováno v:
Cancers, Vol 12, Iss 5, p 1302 (2020)
The success of conventional chimeric antigen receptor (CAR) therapy in the treatment of refractory hematologic malignancies has triggered the development of novel exciting experimental CAR technologies. Among them, adaptor CAR platforms have received
Externí odkaz:
https://doaj.org/article/4ae0838ce2c04dfb8294254bf665dc84
Autor:
Malte von Bonin, Martin Bornhäuser, Marc Schmitz, Stefanie Koristka, Michael Bachmann, Frederick Fasslrinner, Claudia Arndt, Anja Feldmann, Heidi Altmann
Publikováno v:
British Journal of Haematology. 186:735-740
Combinatory therapeutic approaches of different targeted therapies in acute myeloid leukaemia are currently under preclinical/early clinical investigation. To enhance anti-tumour effects, we combined the tyrosine kinase inhibitor (TKI) midostaurin an
Autor:
Martin Bornhäuser, Dietrich W. Beelen, Peter Dreger, Mechthild Krause, Andreas Neubauer, Timo Siepmann, Rita Engenhart-Cabillic, Hans Theodor Eich, Wolfgang E. Berdel, Michael Bätzel, Gerhard Ehninger, Frederick Fasslrinner, Rudolf Trenschel, Michael Kramer, Johannes Schetelig, Kerstin Schäfer-Eckart, Matthias Stelljes, Martin Stuschke, Ute Hegenbart, Michael Stadler, Andreas Burchert
Publikováno v:
The Lancet Haematology. 5:e161-e169
Summary Background The impact of the intensity of conditioning before allogeneic haemopoietic cell transplantation (HCT) has been studied in a randomised phase 3 trial comparing reduced-intensity conditioning with myeloablative conditioning in patien
Autor:
Martin Bornhäuser, Mathias Hänel, Raphael Teipel, Friedrich Stölzel, Anke Morgner, Claudia Arndt, Claudia Brogsitter, Christoph Röllig, Michael Kramer, Johannes Schetelig, Frederick Fasslrinner, Michael Bachmann, Jörg Kotzerke
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 26(4)
Radioimmunotherapy (RIT) has the potential to reduce the incidence of relapse after allogeneic hematopoietic cell transplantation (allo-HCT) in patients with advanced-stage multiple myeloma (MM). In this study, we evaluated the efficacy of RIT in com
Autor:
Frederick Fasslrinner, Marc Schmitz, Liliana Raquel Loureiro, Martin Bornhaeuser, Stefanie Koristka, Claudia Arndt, Anja Feldmann, Gundram Jung, Michael Bachmann
Publikováno v:
BLOOD 134(2019), 5614-5614
Clinical translation of chimeric antigen receptor (CAR) T cell therapy in myeloid malignancies is progressing slowly compared to its success in treatment of B cell malignancies. Clinical experiences with CAR T cell therapies against the currently inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f0b69b88d4472becb2c71b74970e92
https://www.hzdr.de/publications/Publ-30166-1
https://www.hzdr.de/publications/Publ-30166-1