Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Frederick E. Kuhn"'
Publikováno v:
Chest. 102:581-585
Studies have demonstrated that cocaine causes coronary vasoconstriction, but this has been unassociated with myocardial ischemia. Therefore, cocaine seems unlikely to precipitate myocardial infarction in the absence of potentiating factors. We hypoth
Autor:
Frederick E. Kuhn, Charles E. Rackley, David Lu, Emile R. Mohler, Kathleen Reagan, Lowell F. Satler
Publikováno v:
The American Journal of Cardiology. 68:1425-1430
Recent evidence suggests that high-density lipoprotein (HDL) cholesterol has important vasoactive properties which may contribute to its beneficial effects on atherosclerotic coronary artery disease. The endothelium-dependent vasodilator acetylcholin
Autor:
Cynthia M. Tracy, Marc M. Cohen, Allen J. Solomon, Rakesh Jain, Richard A. Gillis, Frederick E. Kuhn, Lisa C. Bachenheimer, Peter B. Corr
Publikováno v:
Journal of Electrocardiology. 24:257-262
The effects of intravenous cocaine (2 mg/kg) were tested on several indices of cardiac electrical activity in sedated dogs. These included sinus rate, PR, AH, and HV intervals; AV nodal effective refractory period (AVNERP); ventricular effective refr
Publikováno v:
Journal of the American College of Cardiology. 16:1481-1491
This study investigated the effect of intravenous cocaine (0.5 to 2 mg/kg body weight) on the coronary circulation and systemic hemodynamics in closed chest sedated dogs. The role of alpha- and beta-adrenoceptor stimulation in mediating these effects
Autor:
Gary L. Schaer, David J. Rodak, Richard A. Gillis, Marc S. Visner, Richard E. Tessel, Frederick E. Kuhn, Linda W. Dickerson, Svea K. Wahlstrom
Publikováno v:
Journal of cardiovascular pharmacology. 33(1)
It has been suggested that cocaine acts directly in the brain to enhance central sympathetic outflow. However, some studies suggested that the cardiovascular effects of cocaine are related to a peripheral action. To characterize further the site of c
Autor:
Hashim K. Erzouki, Victor F.C. Raczkowski, Aloke K. Mandal, Y. M. Hernandez, Richard A. Gillis, Frederick E. Kuhn, Kenneth L. Dretchen
Publikováno v:
Drug and alcohol dependence. 37(3)
Currently, augmentation of sympathetic nervous system function produced by cocaine is thought to be due primarily to stimulation of sympathetic centers in the brain (central effect) and to inhibition of catecholamine uptake into postganglionic sympat
Publikováno v:
Clinical cardiology. 15(12)
Although much emphasis has been placed on the role of cholesterol and lipoproteins in atherosclerotic plaque formation, recent studies suggest that lipids have other vascular actions which may contribute to the pathogenesis of myocardial ischemia. Th
Publikováno v:
American heart journal. 124(5)
Although significant morbidity and mortality have been associated with the combined use of cocaine and ethanol, the cardiovascular effects of this combination are unknown. In this study, the effect of ethanol on cocaine-induced cardiovascular alterat
Autor:
Frederick E. Kuhn, Charles E. Rackley
Publikováno v:
Archives of Internal Medicine. 153:2626
Cardiovasular disease is the leading cause of death in women. Unfortunately, the problem of cardiovascular disease in women has been largely ignored as women have been enrolled in limited numbers or excluded entirely from many of the major trials on
Autor:
Kathleen Reagan, Emile R. Mohler, David Y. Lu, Lowell F. Satler, Charles E. Rackley, Frederick E. Kuhn
Publikováno v:
Journal of the American College of Cardiology. 17:A189