Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Frederick C. Mills"'
Publikováno v:
Annals of the New York Academy of Sciences. 764:136-147
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4397a7f3cb879e29963d1ecab61497ba
https://doi.org/10.1111/j.1749-6632.1995.tb55816.x
https://doi.org/10.1111/j.1749-6632.1995.tb55816.x
Autor:
Qiang Pan, Yanzhong Hu, Lennart Hammarström, Ralph M. Bernstein, Evangelia Pardali, Frederick C. Mills, Paschalis Sideras, Edward E. Max
Publikováno v:
The Journal of Immunology. 164:6380-6386
The human IgH 3′ enhancers, located downstream of each of the two Cα genes, modulate germline (GL) transcription of the IgH genes by influencing the activity of promoter-enhancer complexes upstream of the switch and intervening (I) regions. The re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e197f05fce42ce1547e5a710e072b755
https://doi.org/10.4049/jimmunol.164.12.6380
https://doi.org/10.4049/jimmunol.164.12.6380
Publikováno v:
Gene. 221:215-224
Elk-1 is a transcription factor whose activation by several mitogen-activated protein kinases (MAPKs) mediates the immediate early responses of the c-fos promoter to growth factors and other stimuli. Here, we report the structure of the human elk-1 g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94eeb953f6ac14d2f7d456e1f25de3f
https://doi.org/10.1016/s0378-1119(98)00448-x
https://doi.org/10.1016/s0378-1119(98)00448-x
Publikováno v:
The Journal of Experimental Medicine
To investigate regulation of human immunoglobulin heavy chain expression, we have cloned DNA downstream from the two human Calpha genes, corresponding to the position in the mouse IgH cluster of a locus control region (LCR) that includes an enhancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a90a6f39464b25e80dd4110247e68f
https://doi.org/10.1084/jem.186.6.845
https://doi.org/10.1084/jem.186.6.845
Autor:
Edward E. Max, Florence Malisan, Odette de Bouteiller, Serge Lebecque, Frederick C. Mills, Hector Martinez-Valdez, Jacques Banchereau, Christiane Guret, Yong-Jun Liu
Publikováno v:
Immunity. 4:241-250
Human tonsillar B cells were separated into naive IgD + CD38 − CD23 − (Bm1) and IgD + CD38 − CD23 + (Bm2), germinal center IgD − CD38 + CD23 − centroblasts (Bm3) and IgD − CD38 + CD77 − centrocytes (Bm4), and memory IgD − CD38 − (Bm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90742159989521c021c0f7d4809173c6
https://doi.org/10.1016/s1074-7613(00)80432-x
https://doi.org/10.1016/s1074-7613(00)80432-x
Publikováno v:
Mammalian Genome. 11:938-940
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74a57cb055f1bc1a3511bd0fcc3ac4b
https://doi.org/10.1007/s003350010192
https://doi.org/10.1007/s003350010192
Publikováno v:
Current Protocols in Immunology
When a B lymphocyte changes from synthesizing IgM to synthesizing IgG, IgA, or IgE, this isotype switch is generally accompanied by a unique DNA rearrangement. The protocols in this unit describe two polymerase chain reaction (PCR)-based strategies f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82953f12b900a89eed184733e94a4393
https://pubmed.ncbi.nlm.nih.gov/18432687
https://pubmed.ncbi.nlm.nih.gov/18432687
Complex mechanisms for inhibition of immunoglobulin gene expression in a germinal center B cell line
Publikováno v:
Molecular immunology. 41(1)
CD40 ligation and IL-4 stimulation are critical Th2 cell-derived signals that act on germinal center B cells to stimulate immunoglobulin isotype switching. In addition to this well-known effect, these same Th2 signals have also been reported to inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3e8be6d7381db695e059290ccc50cd
https://pubmed.ncbi.nlm.nih.gov/15140576
https://pubmed.ncbi.nlm.nih.gov/15140576
Publikováno v:
The Journal of Experimental Medicine
When mast cells are activated through their immunoglobulin (Ig)E receptors, release of low molecular weight mediators like histamine is followed by secretion of multiple cytokines, including interleukin (IL)-3, IL-4, IL-5, and granulocyte/macrophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4038459642591da7b45ebea4c9ba7b
https://pubmed.ncbi.nlm.nih.gov/7535336
https://pubmed.ncbi.nlm.nih.gov/7535336
Publikováno v:
Nucleic acids research. 18(24)
We have sequenced the entire human S mu and S gamma 4 immunoglobulin heavy chain class switch regions, and have also completed the sequence of human S epsilon. S mu is composed predominantly of GAGCT and GGGCT pentameric repeats, with these units als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db255156fe03f40e2eee483b790b53c
https://pubmed.ncbi.nlm.nih.gov/2124350
https://pubmed.ncbi.nlm.nih.gov/2124350