Environmental risk factors for cleft lip and palate in low-resource settings: a case-control study

Autor: Allyn Auslander, MPH, Roberta Mckean-Cowdin, PhD, Frederick Brindopke, BS, Kathy Magee, MEd, Melissa DiBona, BA, William Magee, MD DDS

Publikováno v: The Lancet Global Health, Vol 7, Iss , Pp S19- (2019)

Background: Cleft lip with or without palate is the most common birth defect with a global prevalence of 1 in 700 births. Although there is a clear algorithm of care in developed countries, the lack of access to surgery in low-income and middle-incom

Externí odkaz: https://doaj.org/article/f8d35c7ac55440f18747f1920751fe7b

The role of smoke from cooking indoors over an open flame and parental smoking on the risk of cleft lip and palate: A case- control study in 7 low-resource countries

Autor: Allyn Auslander, Sylvia Rakotoarison, William P. Magee, Kathy Magee, Frederick Brindopke, Melissa DiBona, Rijuta Kapoor, Roberta McKean-Cowdin, David V. Conti, Beau Sylvester

Publikováno v: Journal of Global Health

Background Cleft is one of the most common birth defects globally and the lack of access to surgery means millions are living untreated. Smoke exposure from cooking occurs infrequently in developed countries but represents a high-proportion of smoke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f0416326881015a2eb26488e35c27a
https://pubmed.ncbi.nlm.nih.gov/33110573

Parental risk factors for oral clefts among Central Africans, Southeast Asians, and Central Americans

Autor: Annie Vu, Caroline A. Yao, Kathleen S. Magee, Thi-Hai-Duc Nguyen, Athena W.P. Foong, Stephanie Ly, Frederick Brindopke, William P. Magee, Melissa Giron, James W. Baurley, Tamlin Abrahams, Maria Irene Tangco, Jonathan M. Samet, Grace Jang, Yves A. DeClerk, Viet Nguyen, Ugonna Ihenacho, Emily Zolfaghari, Pedro A. Sanchez-Lara, Jane C. Figueiredo

Publikováno v: Birth Defects Research. Part A, Clinical and Molecular Teratology

Background Several lifestyle and environmental exposures have been suspected as risk factors for oral clefts, although few have been convincingly demonstrated. Studies across global diverse populations could offer additional insight given varying typ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7769d5dcbba64d664430fe617c31ce7d
https://doi.org/10.1002/bdra.23417

Intraflagellar transport 88 (IFT88) is crucial for craniofacial development in mice and is a candidate gene for human cleft lip and palate

Autor: William P. Magee, Yuan Yuan, Hua Tian, Jifan Feng, Pedro A. Sanchez-Lara, Jane C. Figueiredo, Jingyuan Li, Frederick Brindopke, Thach-Vu Ho, Yang Chai, Yang Liu

Publikováno v: Human molecular genetics. 26(5)

Ciliopathies are pleiotropic human diseases resulting from defects of the primary cilium, and these patients often have cleft lip and palate. IFT88 is required for the assembly and function of the primary cilia, which mediate the activity of key deve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387c7a03eb86ecccae1f192e11618935
https://pubmed.ncbi.nlm.nih.gov/28069795

Paternal Risk Factors for Oral Clefts in Northern Africans, Southeast Asians, and Central Americans

Autor: Angela Rose Hernandez, Maria Irene Tangco, Allyn Auslander, Madeleine L. Burg, Pedro A. Sanchez-Lara, Thi-Hai-Duc Nguyen, Jane C. Figueiredo, William P. Magee, Frederick Brindopke, Stephanie Ly, Ugonna Ihenacho, Fouzia J. Mahmoudi, Viet Nguyen, Melissa Giron, Kathleen S. Magee, Yves A. DeClerck

Publikováno v: International Journal of Environmental Research and Public Health; Volume 14; Issue 6; Pages: 657
International Journal of Environmental Research and Public Health, Vol 14, Iss 6, p 657 (2017)
International Journal of Environmental Research and Public Health

While several studies have investigated maternal exposures as risk factors for oral clefts, few have examined paternal factors. We conducted an international multi-centered case-control study to better understand paternal risk exposures for oral clef

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6adffec354ed7e91f74814f935f1a33
https://doi.org/10.3390/ijerph14060657