Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Frederick B, Shipley"'
Autor:
Ryann M. Fame, Peter N. Kalugin, Boryana Petrova, Huixin Xu, Paul A. Soden, Frederick B. Shipley, Neil Dani, Bradford Grant, Aja Pragana, Joshua P. Head, Suhasini Gupta, Morgan L. Shannon, Fortunate F. Chifamba, Hannah Hawks-Mayer, Amanda Vernon, Fan Gao, Yong Zhang, Michael J. Holtzman, Myriam Heiman, Mark L. Andermann, Naama Kanarek, Jonathan O. Lipton, Maria K. Lehtinen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Transmission and secretion of signals via the choroid plexus (ChP) brain barrier can modulate brain states via regulation of cerebrospinal fluid (CSF) composition. Here, we developed a platform to analyze diurnal variations in male mouse ChP
Externí odkaz:
https://doaj.org/article/65a235ece7c54d3eb0893bd324dbe181
Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development
Autor:
Huixin Xu, Ryann M. Fame, Cameron Sadegh, Jason Sutin, Christopher Naranjo, Della Syau, Jin Cui, Frederick B. Shipley, Amanda Vernon, Fan Gao, Yong Zhang, Michael J. Holtzman, Myriam Heiman, Benjamin C. Warf, Pei-Yi Lin, Maria K. Lehtinen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Abnormal CSF accumulation in the brain can lead to hydrocephalus. The mechanisms regulating CSF clearance during early development are unclear. Here, the authors show that NKCC1 regulates the clearance of both CSF K+ and fluid volume through the chor
Externí odkaz:
https://doaj.org/article/1226adb34adc4634871fcd9db63032d8
Autor:
Cameron Sadegh, Huixin Xu, Jason Sutin, Benoit Fatou, Suhasini Gupta, Aja Pragana, Milo Taylor, Peter N. Kalugin, Miriam E. Zawadzki, Osama Alturkistani, Frederick B. Shipley, Neil Dani, Ryann M. Fame, Zainab Wurie, Pratik Talati, Riana L. Schleicher, Eric M. Klein, Yong Zhang, Michael J. Holtzman, Christopher I. Moore, Pei-Yi Lin, Aman B. Patel, Benjamin C. Warf, W. Taylor Kimberly, Hanno Steen, Mark L. Andermann, Maria K. Lehtinen
Publikováno v:
Neuron. 111:1591-1608.e4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::548867d0fe701dc76f212ff2cb236834
https://doi.org/10.1016/j.neuron.2023.02.020
https://doi.org/10.1016/j.neuron.2023.02.020
Autor:
Andrew S. Blaeser, Arthur U. Sugden, Jun Zhao, Simone Carneiro-Nascimento, Frederick B. Shipley, Hanaé Carrié, Mark L. Andermann, Dan Levy
Publikováno v:
Cell Reports. 41:111648
The trigeminal sensory innervation of the cranial meninges is thought to serve a nociceptive function and mediate headache pain. However, the activity of meningeal afferents under natural conditions in awake animals remains unexplored. Here, we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cea943ece6820a78fe5de8a01e8d8d
https://doi.org/10.1016/j.celrep.2022.111648
https://doi.org/10.1016/j.celrep.2022.111648
Autor:
Ahram, Jang, Boryana, Petrova, Taek-Chin, Cheong, Miriam E, Zawadzki, Jill K, Jones, Andrew J, Culhane, Frederick B, Shipley, Roberto, Chiarle, Eric T, Wong, Naama, Kanarek, Maria K, Lehtinen
Publikováno v:
Neuron. 110:3288-3301.e8
For many cancer patients, chemotherapy produces untreatable life-long neurologic effects termed chemotherapy-related cognitive impairment (CRCI). We discovered that the chemotherapy methotrexate (MTX) adversely affects oxidative metabolism of non-can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14048acbda954e90df55ed9f6266f744
https://doi.org/10.1016/j.neuron.2022.08.009
https://doi.org/10.1016/j.neuron.2022.08.009
Publikováno v:
Frontiers in Neural Circuits, Vol 8 (2014)
Understanding how an organism's nervous system transforms sensory input into behavioral outputs requires recording and manipulating its neural activity during unrestrained behavior. Here we present an instrument to simultaneously monitor and manipula
Externí odkaz:
https://doaj.org/article/b92ebed1858d492abd9ff9d69be59c94
Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development
Autor:
Yong Zhang, Jason Sutin, Ryann M. Fame, Della Syau, Frederick B. Shipley, Christopher Naranjo, Benjamin C. Warf, Cameron Sadegh, Myriam Heiman, Amanda Vernon, Maria K. Lehtinen, Michael J. Holtzman, Jin Cui, Fan Gao, Huixin Xu, Pei-Yi Lin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Cerebrospinal fluid (CSF) provides vital support for the brain. Abnormal CSF accumulation, such as hydrocephalus, can negatively affect perinatal neurodevelopment. The mechanisms regulating CSF clearance during the postnatal critical period are uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523db8bb35ce7fd9220e1d3f29d179aa
https://doi.org/10.1038/s41467-020-20666-3
https://doi.org/10.1038/s41467-020-20666-3
Autor:
Frederick B. Shipley, Cameron Sadegh, Huixin Xu, Jason Sutin, Benjamin C. Warf, Mark L. Andermann, Michaela Benedict, Maria K. Lehtinen
Publikováno v:
Neurosurgery. 67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf4577f27c44918f571cdf4a92abab50
https://doi.org/10.1093/neuros/nyaa447_574
https://doi.org/10.1093/neuros/nyaa447_574
Autor:
Yong Zhang, Cameron Sadegh, Jason Sutin, Christopher Naranjo, Della Syau, Michael J. Holtzman, Ryann M. Fame, Benjamin C. Warf, Myriam Heiman, Jin Cui, Amanda Vernon, Maria K. Lehtinen, Frederick B. Shipley, Pei-Yi Lin, Fan Gao, Huixin Xu
Cerebrospinal fluid (CSF) provides vital support for the brain. Abnormal CSF accumulation is deleterious for perinatal neurodevelopment, but how CSF leaves the brain during this critical period is unknown. We found in mice a postnatal neurodevelopmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e82d1be7000e3bf5e6d105b17eaf1f0
https://doi.org/10.1101/2020.08.03.234260
https://doi.org/10.1101/2020.08.03.234260
Autor:
Morgan L. Shannon, Huixin Xu, Claire Wyart, Jin Cui, Emily Jang, Maria K. Lehtinen, Eric M. Klein, Mark L. Andermann, Joshua P. Head, Yong Zhang, Michael J. Holtzman, Cameron Sadegh, Frederick B. Shipley, Christopher I. Moore, Glenn J. Goldey, Neil Dani, Ryann M. Fame, Tomas Kirchhausen, Christopher A. Deister, Vanessa I. Flores, Thomas Kishkovich, Kangmin He
Publikováno v:
SSRN Electronic Journal.
The choroid plexus (ChP) epithelium is a source of secreted signaling factors in cerebrospinal fluid (CSF) and a key barrier between blood and brain. Here, we develop imaging tools to interrogate these functions in adult lateral ventricle ChP in whol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce3110d4b56ca6723bb708b154c98a51
https://doi.org/10.2139/ssrn.3554055
https://doi.org/10.2139/ssrn.3554055