Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Frederick A. Saul"'
Autor:
Frederick A. Saul, Brigitte Vulliez-Le Normand, Alexander Boes, Holger Spiegel, Clemens H.M. Kocken, Bart W. Faber, Graham A. Bentley
Publikováno v:
Journal of Structural Biology: X, Vol 10, Iss , Pp 100110- (2024)
Apical Membrane Antigen 1 (AMA1) plays a vital role in the invasion of the host erythrocyte by the malaria parasite, Plasmodium. It is thus an important target for vaccine and anti-malaria therapeutic strategies that block the invasion process. AMA1,
Externí odkaz:
https://doaj.org/article/e07f3fe089b443709f003b70b7311b82
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183198 (2017)
Malaria, a disease endemic in many tropical and subtropical regions, is caused by infection of the erythrocyte by the apicomplexan parasite Plasmodium. Host-cell invasion is a complex process but two Plasmodium proteins, Apical Membrane Antigen 1 (AM
Externí odkaz:
https://doaj.org/article/f3d9d672727a4fb09f1c5715d7ed9876
Autor:
Bart W Faber, Khamisah Abdul Kadir, Roberto Rodriguez-Garcia, Edmond J Remarque, Frederick A Saul, Brigitte Vulliez-Le Normand, Graham A Bentley, Clemens H M Kocken, Balbir Singh
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124400 (2015)
Infection with Plasmodium knowlesi, a zoonotic primate malaria, is a growing human health problem in Southeast Asia. P. knowlesi is being used in malaria vaccine studies, and a number of proteins are being considered as candidate malaria vaccine anti
Externí odkaz:
https://doaj.org/article/e10b9fc972d149b1ae2c819ead5f4200
Autor:
Brigitte Vulliez-Le Normand, Bart W Faber, Frederick A Saul, Marjolein van der Eijk, Alan W Thomas, Balbir Singh, Clemens H M Kocken, Graham A Bentley
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123567 (2015)
The malaria parasite Plasmodium knowlesi, previously associated only with infection of macaques, is now known to infect humans as well and has become a significant public health problem in Southeast Asia. This species should therefore be targeted in
Externí odkaz:
https://doaj.org/article/990ee2b45f2b45609f5d3921acc936b2
Autor:
Brigitte Vulliez-Le Normand, Michelle L Tonkin, Mauld H Lamarque, Susann Langer, Sylviane Hoos, Magali Roques, Frederick A Saul, Bart W Faber, Graham A Bentley, Martin J Boulanger, Maryse Lebrun
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002755 (2012)
Members of the phylum Apicomplexa, which include the malaria parasite Plasmodium, share many features in their invasion mechanism in spite of their diverse host cell specificities and life cycle characteristics. The formation of a moving junction (MJ
Externí odkaz:
https://doaj.org/article/291ea7a19b3f47198e71a11aee704baf
Publikováno v:
Biochemistry. 28:4735-4749
Using X-ray coordinates of antigen-antibody complexes McPC 603, D1.3, and HyHEL-5, we made semiquantitative estimates of Gibbs free energy changes (delta G) accompanying noncovalent complex formation of the McPC 603 Fv fragment with phosphocholine an