Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Frederick A. Ehlert"'
Autor:
Timothy J. Poterucha, Pierre Elias, Sneha S. Jain, Gabriel Sayer, Bjorn Redfors, Daniel Burkhoff, Hannah Rosenblum, Ersilia M. DeFilippis, Aakriti Gupta, Matthew Lawlor, Mahesh V. Madhavan, Jan Griffin, Jayant Raikhelkar, Justin Fried, Kevin J. Clerkin, Andrea Kim, Adler Perotte, Mathew S. Maurer, Deepak Saluja, José Dizon, Frederick A. Ehlert, John P. Morrow, Hirad Yarmohammadi, Angelo B. Biviano, Hasan Garan, LeRoy Rabbani, Martin B Leon, Allan Schwartz, Nir Uriel, Elaine Y. Wan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 1 (2021)
Background Cardiovascular involvement in coronavirus disease 2019 (COVID‐19) is common and leads to worsened mortality. Diagnostic cardiovascular studies may be helpful for resource appropriation and identifying patients at increased risk for death
Externí odkaz:
https://doaj.org/article/7b60e37c6e2842d589229a7438ad7be9
Publikováno v:
学苑 = Gakuen. 962:8-15
G protein-coupled receptors are cell-surface receptors, many of which have conserved motif F(x)6LL in their C-terminal intracellular region. The motif is known to function when the G protein-coupled receptors are exported from the endoplasmic ret
Autor:
Mengchu Li, Huiqun Wang, Peng Huang, Frederick J. Ehlert, Yan Zhang, Yi-Ting Chiu, Yi Zheng, Chongguang Chen, Danni Cao, Lee-Yuan Liu-Chen
Publikováno v:
ACS Chemical Neuroscience. 11:3036-3050
Nalfurafine, a moderately selective kappa opioid receptor (KOR) agonist, is used in Japan for treatment of itch without causing dysphoria or psychotomimesis. Here we characterized the pharmacology of compound 42B, a 3-dehydroxy analogue of nalfurafin
Autor:
Neil M. Nathanson, Jürgen Wess, Rudolf Hammer, R. A. John Challiss, Richard M. Eglen, Fred Mitchelson, David Brown, Sophie J. Bradley, Celine Valant, Heinz Kilbinger, Chris Langmead, Frederick J. Ehlert, Andrew B. Tobin, Noel J. Buckley, Ernst Mutschler, Günter Lambrecht, Arthur Christopoulos, David M. Thal, Roy D. Schwarz, Nigel J. M. Birdsall, Christian C. Felder
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2021
Muscarinic acetylcholine receptors (mAChRs) (nomenclature as agreed by the NC-IUPHAR Subcommittee on Muscarinic Acetylcholine Receptors [50]) are activated by the endogenous agonist acetylcholine. All five (M1-M5) mAChRs are ubiquitously expressed in
Autor:
Frederick J. Ehlert, Nigel J. M. Birdsall, Ernst Mutschler, Heinz Kilbinger, Günter Lambrecht, Neil M. Nathanson, Roy D. Schwarz, Sophie J. Bradley, Richard M. Eglen, Christian C. Felder, David M. Thal, R. A. John Challiss, Rudolf Hammer, Andrew B. Tobin, Jürgen Wess, Arthur Christopoulos, Celine Valant, Noel J. Buckley, Fred Mitchelson, David Brown, Chris Langmead
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2021
Muscarinic acetylcholine receptors (mAChRs) (nomenclature as agreed by the NC-IUPHAR Subcommittee on Muscarinic Acetylcholine Receptors [50]) are activated by the endogenous agonist acetylcholine. All five (M1-M5) mAChRs are ubiquitously expressed in
Autor:
Angelo B. Biviano, David A. Rubin, Nir Uriel, Alexander Kushnir, Timothy J. Poterucha, Geoffrey A. Rubin, Jeremy P. Berman, Hasan Garan, John P. Morrow, Pierre Elias, Deepak Saluja, Marc P. Waase, Mark P. Abrams, Elaine Wan, Hirad Yarmohammadi, Jose Dizon, Frederick A. Ehlert
Publikováno v:
Journal of Cardiovascular Electrophysiology
Introduction Electrocardiographic characteristics in COVID‐19‐related mortality have not yet been reported, particularly in racial/ethnic minorities. Methods and Results We reviewed demographics, laboratory and cardiac tests, medications, and car
Autor:
Danni, Cao, Peng, Huang, Yi-Ting, Chiu, Chongguang, Chen, Huiqun, Wang, Mengchu, Li, Yi, Zheng, Frederick J, Ehlert, Yan, Zhang, Lee-Yuan, Liu-Chen
Publikováno v:
ACS Chem Neurosci
Nalfurafine, a moderately selective kappa opioid receptor (KOR) agonist, is used in Japan for treatment of itch without causing dysphoria or psychotomimesis. Here we characterized pharmacology of compound 42B, a 3-dehydroxy analog of nalfurafine and
Autor:
Mark P. Abrams, Deepak Saluja, Timothy J. Poterucha, Elaine Wan, Hirad Yarmohammadi, Jose Dizon, Alexander Kushnir, Nir Uriel, Marc Waase, Hasan Garan, Geoffrey D. Rubin, John P. Morrow, Angelo B. Biviano, Pierre Elias, Frederick A. Ehlert, Stephanie Jou, Jeremy Berman, Jessica A. Hennessey
Introduction: There is growing evidence that COVID-19 can cause cardiovascular complications. However, there are limited data on the characteristics and importance of atrial arrhythmia (AA) in patients hospitalized with COVID-19. Methods: Data from 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9bd53c9d4f9cb2bdc2668b1ab8ea426
https://doi.org/10.22541/au.159583338.89055001
https://doi.org/10.22541/au.159583338.89055001
Autor:
Frederick J. Ehlert
Drugs and natural ligands induce conformational changes in receptors by selecting for natural active and inactive states of receptors. This process can be modeled by a Monod-Wyman-Changeux (MWC) model, which includes in its scheme of equilibriums an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d36bdc78fa6169a0e060cce05c4fbb70
https://doi.org/10.1016/b978-0-12-816228-6.00009-x
https://doi.org/10.1016/b978-0-12-816228-6.00009-x