Zobrazeno 1 - 10 of 128 pro vyhledávání: '"Frederick A, Villamena"'
1
Trityl Quinodimethane Derivatives as Unimolecular Triple-Function Extracellular EPR Probes for Redox, pH, and Oxygen
Autor: Yalan Feng, Xiaoli Tan, Zhaojun Shi, Frederick A. Villamena, Jay L. Zweier, Yuguang Song, Yangping Liu
Publikováno v: Analytical Chemistry.
Electron paramagnetic resonance (EPR) spectroscopy and imaging coupled with the use of suitable probes is a promising tool for assessment of the tumor microenvironment (TME). Measurement of multiple TME parameters by EPR is very desirable but challen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab888636fa4ca3415747a6dae0257496
https://doi.org/10.1021/acs.analchem.2c03754
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2
Akademický článek
Nutritional Ketosis and Mitohormesis: Potential Implications for Mitochondrial Function and Human Health
Autor: Vincent J. Miller, Frederick A. Villamena, Jeff S. Volek
Publikováno v: Journal of Nutrition and Metabolism, Vol 2018 (2018)
Impaired mitochondrial function often results in excessive production of reactive oxygen species (ROS) and is involved in the etiology of many chronic diseases, including cardiovascular disease, diabetes, neurodegenerative disorders, and cancer. Mode
Externí odkaz: https://doaj.org/article/b1a9494ec2b24460a396f2fa23342158
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3
A ketogenic diet combined with exercise alters mitochondrial function in human skeletal muscle while improving metabolic health
Autor: William J. Kraemer, Cristopher D Crabtree, Teryn S Sapper, Richard A. LaFountain, Vincent J. Miller, Madison L. Kackley, Jay A. Short, Jeff S. Volek, Emily C. Barnhart, W. David Arnold, Parker N. Hyde, Frederick A. Villamena
Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 319:E995-E1007
Animal data indicate that ketogenic diets are associated with improved mitochondrial function, but human data are lacking. We aimed to characterize skeletal muscle mitochondrial changes in response to a ketogenic diet combined with exercise training
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccca982be50242983576ab2759adf289
https://doi.org/10.1152/ajpendo.00305.2020
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4
In Situ EPR Spin Trapping and Competition Kinetics Demonstrate Temperature-Dependent Mechanisms of Synergistic Radical Production by Ultrasonically Activated Persulfate
Autor: William P. Fagan, Frederick A. Villamena, Jay L. Zweier, Linda K. Weavers
Publikováno v: Environmental sciencetechnology. 56(6)
Ultrasound coupled with activated persulfate can synergistically degrade aqueous organic contaminants. Here, in situ electron paramagnetic resonance spin trapping was used to compare radicals produced by ultrasonically activated persulfate (US-PS) an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04b36611756495a11cb4dc311b19666
https://pubmed.ncbi.nlm.nih.gov/35226467
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5
Reevaluation of the Reactivity of Superoxide Radicals with a Sulfonamide Antibiotic, Sulfacetamide:An Experimental and Theoretical Study
Autor: Zonghao Luo, Zongsu Wei, Dionysios D. Dionysiou, Weihua Song, Frederick A. Villamena, Ruiyang Xiao, Wei-Ping Hu, Richard Spinney
Publikováno v: Luo, Z, Spinney, R, Wei, Z, Hu, W-P, Villamena, F A, Song, W, Dionysiou, D D & Xiao, R 2021, ' Reevaluation of the Reactivity of Superoxide Radicals with a Sulfonamide Antibiotic, Sulfacetamide : An Experimental and Theoretical Study ', ACS EST Water, vol. 1, no. 11, pp. 2339-2347 . https://doi.org/10.1021/acsestwater.1c00193
Superoxide radical (O-2(center dot-)) is a ubiquitous reactive oxygen species in sunlit natural waters. Here, we selected sulfacetamide (SCT) as a representative sulfonamide antibiotic to investigate its reactivity with O-2(center dot-), as this reac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7edc08ccfb6e9470a318c6d48b1791d
https://pure.au.dk/portal/da/publications/reevaluation-of-the-reactivity-of-superoxide-radicals-with-a-sulfonamide-antibiotic-sulfacetamide(eda80a5c-9776-4f44-b128-0c7aa18e95dc).html
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6
Dairy milk proteins attenuate hyperglycemia-induced impairments in vascular endothelial function in adults with prediabetes by limiting increases in glycemia and oxidative stress that reduce nitric oxide bioavailability
Autor: Priyankar Dey, Allison N. Labyk, Eunice Mah, Jeff S. Volek, Richard S. Bruno, Frederick A. Villamena, Joshua D. McDonald, Chureeporn Chitchumroonchokchai
Publikováno v: The Journal of Nutritional Biochemistry. 63:165-176
Postprandial hyperglycemia (PPH) transiently impairs vascular endothelial function (VEF) in an oxidative stress-dependent manner by decreasing nitric oxide (NO•) bioavailability. Dairy milk and its proteins attenuate PPH, but whether this improves
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f962908d381bff56073b9b29fe2322bb
https://doi.org/10.1016/j.jnutbio.2018.09.018
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7
Membrane-specific spin trap, 5-dodecylcarbamoyl-5-N-dodecylacetamide-1-pyroline-N-oxide (diC12PO): theoretical, bioorthogonal fluorescence imaging and EPR studies
Autor: Yongbin Han, Frederick A. Villamena, Jay L. Zweier, Jeff Kuret, Colwyn A. Headley, Antal Rockenbauer, Joseph M Macklin, Juliana M Freisen, Claire N. Hoffman
Publikováno v: Organic & Biomolecular Chemistry. 17:7694-7705
Membranous organelles are major endogenous sources of reactive oxygen and nitrogen species. When present at high levels, these species can cause macromolecular damage and disease. To better detect and scavenge free radical forms of the reactive speci
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6f81c5df587c195baee49ec0b197e05
https://doi.org/10.1039/c9ob01334b
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9
Clinical Probes for ROS and Oxidative Stress
Autor: Pedro L. Zamora, Frederick A. Villamena
Publikováno v: Measuring Oxidants and Oxidative Stress in Biological Systems ISBN: 9783030473174
Electron paramagnetic resonance (EPR) spectroscopy is considered as a valuable tool in the determination and characterization of free radicals in vitro and in animal models; however, its use in humans presents technical challenges. While spin traps a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c9dd09da287ef4f88c94ab40c2a3912
https://doi.org/10.1007/978-3-030-47318-1_3
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10
Akademický článek
Diesterified nitrone rescues nitroso-redox levels and increases myocyte contraction via increased SR Ca(2+) handling.
Autor: Christopher J Traynham, Steve R Roof, Honglan Wang, Robert A Prosak, Lifei Tang, Serge Viatchenko-Karpinski, Hsiang-Ting Ho, Ira O Racoma, Dominic J Catalano, Xin Huang, Yongbin Han, Shang-U Kim, Sandor Gyorke, George E Billman, Frederick A Villamena, Mark T Ziolo
Publikováno v: PLoS ONE, Vol 7, Iss 12, p e52005 (2012)
Nitric oxide (NO) and superoxide (O(2) (-)) are important cardiac signaling molecules that regulate myocyte contraction. For appropriate regulation, NO and O(2) (.-) must exist at defined levels. Unfortunately, the NO and O(2) (.-) levels are altered
Externí odkaz: https://doaj.org/article/8e0cb70510354f61a6e1f4f77eeaac16
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