Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Frederick, Colbourne"'
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0302008 (2024)
Malnutrition after stroke may lessen the beneficial effects of rehabilitation on motor recovery through influences on both brain and skeletal muscle. Enriched rehabilitation (ER), a combination of environmental enrichment and forelimb reaching practi
Externí odkaz:
https://doaj.org/article/605b263d8f5f4b8599f8c2ac955500c3
Publikováno v:
PLoS ONE, Vol 18, Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/c4b4f401fa86403d9be3a30e1b70edaf
Autor:
Turner S. Baker, Christopher P. Kellner, Frederick Colbourne, Fred Rincon, Rainer Kollmar, Neeraj Badjatia, Neha Dangayach, J. Mocco, Magdy H. Selim, Patrick Lyden, Kees Polderman, Stephan Mayer
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Background and purposeTherapeutic hypothermia (TH), or targeted temperature management (TTM), is a classic treatment option for reducing inflammation and potentially other destructive processes across a wide range of pathologies, and has been success
Externí odkaz:
https://doaj.org/article/8ddd7730ab2c4ba58cb1e5fa3b2524d8
Publikováno v:
Brain Hemorrhages, Vol 2, Iss 1, Pp 34-48 (2021)
As with ischemic and traumatic brain injury, raised intracranial pressure (ICP) is a common life-threatening complication of intracerebral hemorrhage (ICH). Elevated ICP can lead to cerebral ischemia, impaired cerebrospinal fluid flow, and brain hern
Externí odkaz:
https://doaj.org/article/43bfc3a0cefc484a9a763bb52034d42b
Autor:
Anna C. J. Kalisvaart, Cassandra M. Wilkinson, Sherry Gu, Tiffany F. C. Kung, Jerome Yager, Ian R. Winship, Frank K. H. van Landeghem, Frederick Colbourne
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Abstract High intracranial pressure (ICP) can impede cerebral blood flow resulting in secondary injury or death following severe stroke. Compensatory mechanisms include reduced cerebral blood and cerebrospinal fluid volumes, but these often fail to p
Externí odkaz:
https://doaj.org/article/0cfda1b4ad5d4c7287732a62aeecb83d
Autor:
Cassandra M. Wilkinson, Aristeidis H. Katsanos, Noam H. Sander, Tiffany F. C. Kung, Frederick Colbourne, Ashkan Shoamanesh
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Patients with intracerebral hemorrhage (ICH) are at increased risk for major ischemic cardiovascular and cerebrovascular events. However, the use of preventative antithrombotic therapy can increase the risk of ICH recurrence and worsen ICH-related ou
Externí odkaz:
https://doaj.org/article/fa014dc62ca546f7ac2c6c3055ec5a12
Publikováno v:
Brain Circulation, Vol 5, Iss 4, Pp 169-178 (2019)
Therapeutic hypothermia (TH) is a potent neuroprotectant against multiple forms of brain injury, but in some cases, prolonged cooling is needed. Such cooling protocols raise the risk that TH will directly or indirectly impact neuroplasticity, such as
Externí odkaz:
https://doaj.org/article/54c99bb756494f8db7f0fd6786908acd
Autor:
Lane J. Liddle, Christine A. Dirks, Brittany A. Fedor, Mohammed Almekhlafi, Frederick Colbourne
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
Background: As not all ischemic stroke patients benefit from currently available treatments, there is considerable need for neuroprotective co-therapies. Therapeutic hypothermia is one such co-therapy, but numerous issues have hampered its clinical u
Externí odkaz:
https://doaj.org/article/198455bf679d4d7b99419aa7a7b8c75e
Autor:
Tiffany F C Kung, Cassandra M Wilkinson, Christine A Dirks, Glen C Jickling, Frederick Colbourne
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252584 (2021)
Intracerebral hemorrhage (ICH) is a devastating insult with few effective treatments. Edema and raised intracranial pressure contribute to poor outcome after ICH. Glibenclamide blocks the sulfonylurea 1 transient receptor potential melastatin 4 (Sur1
Externí odkaz:
https://doaj.org/article/aa5fe3b5564147809f58863890600c95
Autor:
Britt A. Fedor, Anna C.J. Kalisvaart, Shivani Ralhan, Tiffany F.C. Kung, Maxwell MacLaren, Frederick Colbourne
Publikováno v:
Neurorehabilitation and Neural Repair. 36:788-799
Background The formation and degradation of an intracerebral hemorrhage causes protracted cell death, and an extended window for intervention. Experimental studies find that rehabilitation mitigates late cell death, with accelerated hematoma clearanc