Association Between Insulin‐Like Growth Factor‐1 and Social Cognition in Huntington's Disease

Autor: Cecilia Gil‐Polo, Saul‐Indra Martinez‐Horta, Frederic Sampedro Santalo, María Martín‐Palencia, Simón Gundín‐Menéndez, Pilar Alvarez‐Baños, Laura Maza‐Pereg, Sara Calvo, Carla Collazo, Esther Alonso‐García, Esther Riñones‐Mena, Angela Arrabal‐Alonso, Juan Núñez Rodriguez, Miriam Saiz‐Rodriguez, Laura Aguado, Natividad Mariscal, Ignacio Muñoz‐Siscart, Dolores Piñeiro, Jessica Rivadeneyra, Monica Diez‐Fairen, Irene Miguel‐Pérez, Esther Cubo

Insulin-like growth factor 1 (IGF-1) seems to be involved in the neural circuits associated with social cognition and brain structure.
Study funded by Gerencia Regional de Salud de Castilla y Leon (Sacyl GRS 1768/A/18).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ecbb8245f65556f4e4b9531fbb84b7
http://hdl.handle.net/10259/7415

Clinical manifestations of homozygote allele carriers in Huntington disease

Autor: Maria A. Ramos-Arroyo, Sara Calvo, Natividad Mariscal, Frederic Sampedro Santalo, Laura Aguado, Saul-Indra Martinez-Horta, Ignacio Muñoz, Esther Cubo, Cecilia Gil-Polo, Katia Llano, Asunción Martínez Descalls, Aranzazu Gutierrez, Dolores Diaz

Publikováno v: NEUROLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Objective Because patients homozygous for Huntington disease (HD) receive the gain-of-function mutation in a double dose, one would expect a more toxic effect in homozygotes than in heterozygotes. Our aim was to investigate the phenotypic differences

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f270d995e4d84fd59088e6bb73f03c6c
https://pubmed.ncbi.nlm.nih.gov/32312883