Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Frederic S. Michel"'
Publikováno v:
Physiological Reports, Vol 12, Iss 20, Pp n/a-n/a (2024)
Abstract Hypertension drives the development of concentric left ventricular hypertrophy (LVH). However, the relative contribution of pentraxin‐3 (PTX‐3), a novel marker for inflammatory cardiovascular disease, in the hypertrophic response to pres
Externí odkaz:
https://doaj.org/article/36ecdf95be89410f9e8e3f182ca0e893
Autor:
Sulè Gunter, Frederic S Michel, Serena S Fourie, Mikayra Singh, Regina le Roux, Ashmeetha Manilall, Lebogang P Mokotedi, Aletta M E Millen
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0264558 (2022)
Chronic inflammation causes dysregulated expression of microRNAs. Aberrant microRNA expression is associated with endothelial dysfunction. In this study we determined whether TNF-α inhibition impacted the expression of miRNA-146a-5p and miRNA-155-5p
Externí odkaz:
https://doaj.org/article/38944472a26848d9bfac0d26f732980a
Autor:
Lebogang Mokotedi, Frederic S Michel, Conrad Mogane, Monica Gomes, Angela J Woodiwiss, Gavin R Norton, Aletta M E Millen
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230657 (2020)
BACKGROUND:High-grade inflammation may play a pivotal role in the pathogenesis of left ventricular (LV) dysfunction. Evidence to support a role of systemic inflammation in mediating impaired LV function in experimental models of rheumatoid arthritis
Externí odkaz:
https://doaj.org/article/f66754cb9d1c493d91a146c639e3a4da
Autor:
Sulè Gunter, Frederic S. Michel, Serena S. Fourie, Mikayra Singh, Regina le Roux, Ashmeetha Manilall, Lebogang P. Mokotedi, Aletta M. E. Millen
Publikováno v:
PloS one. 17(2)
Chronic inflammation causes dysregulated expression of microRNAs. Aberrant microRNA expression is associated with endothelial dysfunction. In this study we determined whether TNF-α inhibition impacted the expression of miRNA-146a-5p and miRNA-155-5p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b25696c5c591baa34cc3b7286adf4a1
https://pubmed.ncbi.nlm.nih.gov/35213638
https://pubmed.ncbi.nlm.nih.gov/35213638
Autor:
Monica Gomes, Aletta M.E. Millen, Lebogang Mokotedi, Frederic S. Michel, Angela J. Woodiwiss, Conrad Mogane, Gavin R. Norton
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230657 (2020)
PLoS ONE
PLoS ONE
Background High-grade inflammation may play a pivotal role in the pathogenesis of left ventricular (LV) dysfunction. Evidence to support a role of systemic inflammation in mediating impaired LV function in experimental models of rheumatoid arthritis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d3086869d369b48ff076a37d2c56c8
https://doaj.org/article/f66754cb9d1c493d91a146c639e3a4da
https://doaj.org/article/f66754cb9d1c493d91a146c639e3a4da
Autor:
Lebogang Mokotedi, Linda Tsang, Chanel Robinson, Patrick H Dessein, Gavin R. Norton, Aletta M.E. Millen, Ahmed Solomon, Sule Gunter, Angela J. Woodiwiss, Frederic S. Michel
Publikováno v:
Journal of cardiovascular translational research. 12(6)
Rheumatoid arthritis (RA) impacts arterial and diastolic function. This study examined whether arterial properties can determine diastolic function in RA. In 173 RA patients, arterial function measures including carotid femoral pulse wave velocity (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9210c3ec2f9389c3f3c1edcf6242418
https://pubmed.ncbi.nlm.nih.gov/31119564
https://pubmed.ncbi.nlm.nih.gov/31119564
Autor:
Lebogang Mokotedi, Conrad Mogane, Monica Gomes, Aletta M.E. Millen, Frederic S. Michel, Gavin R. Norton, Angela J. Woodiwiss
Publikováno v:
European Journal of Pharmacology. 865:172786
We determined the role of high-grade inflammation on endothelial function and its association with biomarkers of endothelial dysfunction in collagen-induced arthritis. Sprague-Dawley rats were divided into a control (n = 12) or collagen-induced arthr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c30d7023ad58f2fcdf2693379a551e
https://doi.org/10.1016/j.ejphar.2019.172786
https://doi.org/10.1016/j.ejphar.2019.172786
Publikováno v:
THURSDAY, 14 JUNE 2018.
Background Patients with rheumatoid arthritis (RA) experience an increased risk of developing heart failure with a preserved ejection fraction. Although there is some evidence to support a role of chronic inflammation in the pathogenesis of impaired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7c5ad065f949a7c81e7e45858f7af11
https://doi.org/10.1136/annrheumdis-2018-eular.5313
https://doi.org/10.1136/annrheumdis-2018-eular.5313
Autor:
Sule Gunter, Patrick H Dessein, Linda Tsang, Angela J. Woodiwiss, Frederic S. Michel, Gavin R. Norton, Chanel Robinson, Lebogang Mokotedi, Aletta M.E. Millen
Publikováno v:
Saturday, 16 JUNE 2018.
Background Patients with rheumatoid arthritis (RA) experience an increased frequency of heart failure with a preserved ejection fraction (HFpEF) (1). The treatment of HFpEF is currently suboptimal. Elucidation of the underlying pathophysiological mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18ca143c99a19352bb5b1ba033f2f0b2
https://doi.org/10.1136/annrheumdis-2018-eular.5090
https://doi.org/10.1136/annrheumdis-2018-eular.5090
Autor:
Olebogeng H.I. Majane, Gavin R. Norton, Glenda Norman, Pinhas Sareli, Aletta M.E. Millen, Carlos D. Libhaber, Angela J. Woodiwiss, Frederic S. Michel
Publikováno v:
International Journal of Cardiology. 196:81-87
Although the adipokine resistin may play a role in heart failure, the mechanisms of this effect are uncertain. Relations with left ventricular mass (LVM) and function are uncertain.In 739 randomly selected participants from a community sample (43.6%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2be0132d4093c4c178f39cc75106779
https://doi.org/10.1016/j.ijcard.2015.05.184
https://doi.org/10.1016/j.ijcard.2015.05.184