Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Frederic S. Arendrup"'
Autor:
Aida Rodríguez López, Maria H. Jørgensen, Jesper F. Havelund, Frederic S. Arendrup, Srinivasa Prasad Kolapalli, Thorbjørn M. Nielsen, Eva Pais, Carsten Jörn Beese, Ahmad Abdul-Al, Anna Constance Vind, Jiri Bartek, Simon Bekker-Jensen, Marta Montes, Panagiotis Galanos, Nils Faergeman, Lotta Happonen, Lisa B. Frankel
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113381- (2023)
Summary: Oncogene-induced senescence (OIS) is a persistent anti-proliferative response that acts as a barrier against malignant transformation. During OIS, cells undergo dynamic remodeling, which involves alterations in protein and organelle homeosta
Externí odkaz:
https://doaj.org/article/194106ee156b484ca5a608d3be2c0d91
Autor:
Marta Montes, Michal Lubas, Frederic S. Arendrup, Bettina Mentz, Neha Rohatgi, Sarunas Tumas, Lea M. Harder, Anders J. Skanderup, Jens S. Andersen, Anders H. Lund
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Senescence-associated secretory phenotype (SASP) involves secretion of factors such as pro-inflammatory cytokines. Here the authors show that MIR31HG regulates the expression and secretion of a subset of SASP components that induce paracrine invasion
Externí odkaz:
https://doaj.org/article/8da6f54bfa9d4666b2534cafaba5a56a
Autor:
Tomasz M. Wróbel, Oksana Rogova, Katyayani Sharma, Maria Natalia Rojas Velazquez, Amit V. Pandey, Flemming Steen Jørgensen, Frederic S. Arendrup, Kasper L. Andersen, Fredrik Björkling
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 165 (2022)
Twenty new compounds, targeting CYP17A1, were synthesized, based on our previous work on a benzimidazole scaffold, and their biological activity evaluated. Inhibition of CYP17A1 is an important modality in the treatment of prostate cancer, which rema
Externí odkaz:
https://doaj.org/article/6056628f75504571a6d1428b90bed8b1
Autor:
Frederic S Arendrup, Jens S. Andersen, Marta Montes, Anders H. Lund, Sarunas Tumas, Lea M. Harder, Anders Jacobsen Skanderup, Neha Rohatgi, Bettina Mentz, Michal Lubas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Montes, M, Lubas, M, Arendrup, F S, Mentz, B, Rohatgi, N, Tumas, S, Harder, L M, Skanderup, A J, Andersen, J S & Lund, A H 2021, ' The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype ', Nature Communications, vol. 12, no. 1, 2459 . https://doi.org/10.1038/s41467-021-22746-4
Montes, M, Lubas, M, Arendrup, F S, Mentz, B, Rohatgi, N, Tumas, S, Harder, L M, Skanderup, A J, Andersen, J S & Lund, A H 2021, ' The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype ', Nature Communications, vol. 12, no. 1, 2459, pp. 1-17 . https://doi.org/10.1038/s41467-021-22746-4
Nature Communications
Montes, M, Lubas, M, Arendrup, F S, Mentz, B, Rohatgi, N, Tumas, S, Harder, L M, Skanderup, A J, Andersen, J S & Lund, A H 2021, ' The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype ', Nature Communications, vol. 12, no. 1, 2459 . https://doi.org/10.1038/s41467-021-22746-4
Montes, M, Lubas, M, Arendrup, F S, Mentz, B, Rohatgi, N, Tumas, S, Harder, L M, Skanderup, A J, Andersen, J S & Lund, A H 2021, ' The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype ', Nature Communications, vol. 12, no. 1, 2459, pp. 1-17 . https://doi.org/10.1038/s41467-021-22746-4
Oncogene-induced senescence provides a barrier against malignant transformation. However, it can also promote cancer through the secretion of a plethora of factors released by senescent cells, called the senescence associated secretory phenotype (SAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546e726c91808867332c4f90a83cb157
https://doaj.org/article/8da6f54bfa9d4666b2534cafaba5a56a
https://doaj.org/article/8da6f54bfa9d4666b2534cafaba5a56a
Autor:
Jens S. Andersen, Lea M. Harder, Anders H. Lund, Neha Rohatgi, Frederic S Arendrup, Marta Montes, Anders Jacobsen Skanderup, Michael Lubas, Sarunas Tumas, Bettina Mentz
Senescent cells secrete cytokines, chemokines and growth factors collectively known as the senescence-associated secretory phenotype (SASP) which can reinforce senescence and activate the immune response. However, it can also negatively impact neighb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6911b937e9e61ec3a109a5eb3cf7b4b
https://doi.org/10.21203/rs.3.rs-57840/v1
https://doi.org/10.21203/rs.3.rs-57840/v1
Publikováno v:
Endocrine Connections, Vol 7, Iss 1, Pp 149-158 (2018)
Endocrine Connections
Endocrine Connections, 2018, 7 (1), pp.149-158. ⟨10.1530/EC-17-0298⟩
Endocrine Connections, BioScientifica Ltd., 2018, 7 (1), pp.149-158. ⟨10.1530/EC-17-0298⟩
Endocrine Connections
Endocrine Connections, 2018, 7 (1), pp.149-158. ⟨10.1530/EC-17-0298⟩
Endocrine Connections, BioScientifica Ltd., 2018, 7 (1), pp.149-158. ⟨10.1530/EC-17-0298⟩
Concern has been raised over chemical-induced disruption of ovary development during fetal life resulting in long-lasting consequences only manifesting themselves much later during adulthood. A growing body of evidence suggests that prenatal exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de551a09d8bcfbd38fea229d0367eaa2
http://www.endocrineconnections.com/content/7/1/149.full
http://www.endocrineconnections.com/content/7/1/149.full