Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Frederic Lluis"'
Autor:
Jonathan Sai‐Hong Chui, Teresa Izuel‐Idoype, Alessandra Qualizza, Rita Pires deAlmeida, Lindsey Piessens, Bernard K. van derVeer, Gert Vanmarcke, Aneta Malesa, Paraskevi Athanasouli, Ruben Boon, Joris Vriens, Leo vanGrunsven, Kian Peng Koh, Catherine M. Verfaillie, Frederic Lluis
Publikováno v:
Advanced Science, Vol 11, Iss 7, Pp n/a-n/a (2024)
Abstract Terminally differentiated cells are commonly regarded as the most stable cell state in adult organisms, characterized by growth arrest while fulfilling their specialized functions. A better understanding of the mechanisms involved in promoti
Externí odkaz:
https://doaj.org/article/d3f33e15b1534ffcbb0747b487db0584
Autor:
Paraskevi Athanasouli, Martina Balli, Anchel De Jaime-Soguero, Annekatrien Boel, Sofia Papanikolaou, Bernard K. van der Veer, Adrian Janiszewski, Tijs Vanhessche, Annick Francis, Youssef El Laithy, Antonio Lo Nigro, Francesco Aulicino, Kian Peng Koh, Vincent Pasque, Maria Pia Cosma, Catherine Verfaillie, An Zwijsen, Björn Heindryckx, Christoforos Nikolaou, Frederic Lluis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Signal transduction and gene expression regulation via downstream transcription factors shape the early mammalian embryo. Here the authors show that Wnt/TCF7L1 transcriptional repressive activity is required for primitive endoderm lineage formation.
Externí odkaz:
https://doaj.org/article/8c6090935fbd461d86225955994338e9
Autor:
Willy Antoni Abreu de Oliveira, Youssef El Laithy, Alejandra Bruna, Daniela Annibali, Frederic Lluis
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The Wnt cascade is a primordial developmental signaling pathway that plays a myriad of essential functions throughout development and adult homeostasis in virtually all animal species. Aberrant Wnt activity is implicated in embryonic and tissue morph
Externí odkaz:
https://doaj.org/article/ac0ce49d938a4d98a3b6ebdb2c887e44
Autor:
Willy Antoni Abreu de Oliveira, Stijn Moens, Youssef El Laithy, Bernard K. van der Veer, Paraskevi Athanasouli, Emanuela Elsa Cortesi, Maria Francesca Baietti, Kian Peng Koh, Juan-Jose Ventura, Frédéric Amant, Daniela Annibali, Frederic Lluis
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Triple-Negative Breast Cancer (TNBC) is the most aggressive breast cancer subtype, characterized by limited treatment options and higher relapse rates than hormone-receptor-positive breast cancers. Chemotherapy remains the mainstay treatment for TNBC
Externí odkaz:
https://doaj.org/article/5758a8c5ff9c45e9821c7540ea658c47
Autor:
Antonio Lo Nigro, Anchel de Jaime-Soguero, Rita Khoueiry, Dong Seong Cho, Giorgia Maria Ferlazzo, Ilaria Perini, Vanesa Abon Escalona, Xabier Lopez Aranguren, Susana M. Chuva de Sousa Lopes, Kian Peng Koh, Pier Giulio Conaldi, Wei-Shou Hu, An Zwijsen, Frederic Lluis, Catherine M. Verfaillie
Publikováno v:
Stem Cell Reports, Vol 8, Iss 2, Pp 318-333 (2017)
In early mouse pre-implantation development, primitive endoderm (PrE) precursors are platelet-derived growth factor receptor alpha (PDGFRα) positive. Here, we demonstrated that cultured mouse embryonic stem cells (mESCs) express PDGFRα heterogeneou
Externí odkaz:
https://doaj.org/article/aa9c6edd25094bb88a2946552f3a39cd
Autor:
Martina Balli, Jonathan Sai-Hong Chui, Paraskevi Athanasouli, Willy Antoni Abreu de Oliveira, Youssef El Laithy, Maurilio Sampaolesi, Frederic Lluis
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Impaired wound healing and tissue regeneration have severe consequences on the patient’s quality of life. Micrograft therapies are emerging as promising and affordable alternatives to improve skin regeneration by enhancing the endogenous wound repa
Externí odkaz:
https://doaj.org/article/1e8bf41a0de64f358243d14569efa0e2
Autor:
Anchel De Jaime-Soguero, Francesco Aulicino, Gokhan Ertaylan, Anna Griego, Aniello Cerrato, Aravind Tallam, Antonio Del Sol, Maria Pia Cosma, Frederic Lluis
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006682 (2017)
Understanding the mechanisms regulating cell cycle, proliferation and potency of pluripotent stem cells guarantees their safe use in the clinic. Embryonic stem cells (ESCs) present a fast cell cycle with a short G1 phase. This is due to the lack of e
Externí odkaz:
https://doaj.org/article/856d9520323d4f67b191aca87f3f0e0c
Publikováno v:
Stem Cell Reports, Vol 2, Iss 5, Pp 707-720 (2014)
Cyclic activation of the Wnt/β-catenin signaling pathway controls cell fusion-mediated somatic cell reprogramming. TCFs belong to a family of transcription factors that, in complex with β-catenin, bind and transcriptionally regulate Wnt target gene
Externí odkaz:
https://doaj.org/article/0d2d95e62ca24034b60319aa17fcb1b8
Autor:
Dick W. Zijlmans, Irene Talon, Sigrid Verhelst, Adam Bendall, Karlien Van Nerum, Alok Javali, Andrew A. Malcolm, Sam S. F. A. van Knippenberg, Laura Biggins, San Kit To, Adrian Janiszewski, Danielle Admiraal, Ruth Knops, Nikky Corthout, Bradley P. Balaton, Grigorios Georgolopoulos, Amitesh Panda, Natarajan V. Bhanu, Amanda J. Collier, Charlene Fabian, Ryan N. Allsop, Joel Chappell, Thi Xuan Ai Pham, Michael Oberhuemer, Cankat Ertekin, Lotte Vanheer, Paraskevi Athanasouli, Frederic Lluis, Dieter Deforce, Joop H. Jansen, Benjamin A. Garcia, Michiel Vermeulen, Nicolas Rivron, Maarten Dhaenens, Hendrik Marks, Peter J. Rugg-Gunn, Vincent Pasque
Publikováno v:
Nature Cell Biology, 24, pp. 858-871
Nature Cell Biology, 24, 858-871
Nature Cell Biology
NATURE CELL BIOLOGY
Nature Cell Biology, 24, 858-871
Nature Cell Biology
NATURE CELL BIOLOGY
Funder: The Marks lab is supported by an NWO-XS grant
Funder: M.V. is part of the Oncode Institute, which is partly funded by the Dutch Cancer Society
Funder: D.W.Z. is part of the Oncode Institute, which is partly funded by the Dutch Cance
Funder: M.V. is part of the Oncode Institute, which is partly funded by the Dutch Cancer Society
Funder: D.W.Z. is part of the Oncode Institute, which is partly funded by the Dutch Cance
Autor:
Jonathan Sai-Hong Chui, Teresa Izuel-Idoype, Alessandra Qualizza, Rita Pires de Almeida, Bernard K. van der Veer, Gert Vanmarcke, Paraskevi Athanasouli, Ruben Boon, Joris Vriens, Kian Peng Koh, Leo van Grunsven, Catherine M. Verfaillie, Frederic Lluis
Terminally differentiated cells are regarded as the most stable and common cell state in adult organisms as they reside in growth arrest and carry out their cellular function. Improving our understanding of the mechanisms involved in promoting cell c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaac3c39526a087796b28e4705c991b9
https://doi.org/10.1101/2023.04.14.536882
https://doi.org/10.1101/2023.04.14.536882