Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Frederic Koch"'
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Mouse embryonic stem cells (mESCs) and mouse epiblast stem cells (mEpiSCs) are the pluripotent stem cells (PSCs), derived from the inner cell mass (ICM) of preimplantation embryos at embryonic day 3.5 (E3.5) and postimplantation embryos at E5.5-E7.5,
Externí odkaz:
https://doaj.org/article/9fcc7a9bf47c41d8a0daa6ee7b97c6da
Autor:
Nicolas Descostes, Martin Heidemann, Lionel Spinelli, Roland Schüller, Muhammad Ahmad Maqbool, Romain Fenouil, Frederic Koch, Charlène Innocenti, Marta Gut, Ivo Gut, Dirk Eick, Jean-Christophe Andrau
Publikováno v:
eLife, Vol 3 (2014)
In mammals, the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II consists of 52 conserved heptapeptide repeats containing the consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Post-translational modifications of the CTD coordinate the tr
Externí odkaz:
https://doaj.org/article/56988b85933f4d25b9e33e45db564b68
Autor:
Pavel Tsaytler, Jinhua Liu, Gaby Blaess, Dennis Schifferl, Jesse V. Veenvliet, Lars Wittler, Bernd Timmermann, Bernhard G. Herrmann, Frederic Koch
Publikováno v:
Development
Cardiac lineage specification in the mouse is controlled by TGFβ and WNT signaling. From fly to fish, BMP has been identified as an indispensable heart inducer. A detailed analysis of the role of Bmp4 and its effectors Smad1/5, however, was still mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aff1e80534da7ec746279c944052633
https://doi.org/10.1242/dev.201450
https://doi.org/10.1242/dev.201450
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2021 (2021)
Stem Cells International, Vol 2021 (2021)
Mouse embryonic stem cells (mESCs) and mouse epiblast stem cells (mEpiSCs) are the pluripotent stem cells (PSCs), derived from the inner cell mass (ICM) of preimplantation embryos at embryonic day 3.5 (E3.5) and postimplantation embryos at E5.5-E7.5,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5cf6055484d7737e3b3246be889e32
https://doi.org/10.1155/2021/8818356
https://doi.org/10.1155/2021/8818356
Autor:
Bernhard G. Herrmann, Dennis Schifferl, Lars Wittler, Manuela Scholze-Wittler, Frederic Koch, Jesse V. Veenvliet
Publikováno v:
Development
Development (Cambridge, England)
article-version (VoR) Version of Record
Development (Cambridge, England)
article-version (VoR) Version of Record
The node-streak border region comprising notochord progenitor cells (NPCs) at the posterior node and neuro-mesodermal progenitor cells (NMPs) in the adjacent epiblast is the prime organizing center for axial elongation in mouse embryos. The T-box tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23036d9e2167cdc8e973557066778f7c
https://hdl.handle.net/21.11116/0000-0009-B873-621.11116/0000-0009-B875-4
https://hdl.handle.net/21.11116/0000-0009-B873-621.11116/0000-0009-B875-4
Autor:
Léo Guignard, Alexander Meissner, Leah Haut, Helene Kretzmer, Bernhard G. Herrmann, Dennis Schifferl, Manuela Scholze-Wittler, Adriano Bolondi, Jesse V. Veenvliet, Bernd Timmermann, Milena Pustet, Abhishek Sampath Kumar, Frederic Koch, Lars Wittler, René Buschow, Simon Heimann
Publikováno v:
Science
Trunk formation in a dish Building mammalian embryos from self-organizing stem cells in culture would accelerate the investigation of morphogenetic and differentiation processes that shape the body plan. Veenvliet et al. report a method for generatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc535e98aa724322b5517e1c9e211032
https://doi.org/10.1126/science.aba4937
https://doi.org/10.1126/science.aba4937
Autor:
Frederic Koch, Olivier Joffre, Amal Zine El Aabidine, Tom Sexton, Romain Fenouil, Jean-Christophe Andrau, Anne Molitor, Lan T.M. Dao, Muhammad Ahmad Maqbool, Nezih Karasu, Léo Pioger, Georges Lacaud, Salvatore Spicuglia, Francois van Laethem, Ivo Gut, Guillaume Charbonnier, Marta Gut, Sebastian Amigorena
Publikováno v:
Maqbool, M A, Pioger, L, El Aabidine, A Z, Karasu, N, Molitor, A M, Dao, L T M, Charbonnier, G, van Laethem, F, Fenouil, R, Koch, F, Lacaud, G, Gut, I, Gut, M, Amigorena, S, Joffre, O, Sexton, T, Spicuglia, S & Andrau, J-C 2020, ' Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation ', Cell Reports, vol. 32, no. 7, pp. 108048 . https://doi.org/10.1016/j.celrep.2020.108048
Cell Reports
Cell Reports, 2020, 32, ⟨10.1016/j.celrep.2020.108048⟩
Cell Reports, Elsevier Inc, 2020, 32, ⟨10.1016/j.celrep.2020.108048⟩
Cell Reports
Cell Reports, 2020, 32, ⟨10.1016/j.celrep.2020.108048⟩
Cell Reports, Elsevier Inc, 2020, 32, ⟨10.1016/j.celrep.2020.108048⟩
During thymic development and upon peripheral activation, T cells undergo extensive phenotypic and functional changes coordinated by lineage-specific developmental programs. To characterize the regulatory landscape controlling T cell identity, we per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3860bff576c8e4a0430b6ab759f0e31
https://research.manchester.ac.uk/en/publications/1beaedc3-fb54-4abc-8c8f-880dd2f6c67e
https://research.manchester.ac.uk/en/publications/1beaedc3-fb54-4abc-8c8f-880dd2f6c67e
Publikováno v:
Transcription
Pioneer transcription factors are defined by their ability to bind nucleosome-occupied regions. Here, we discuss the properties of nucleosomes bound by pioneers at enhancer regions. We describe how select pioneers bind nucleosome-occupied or -deplete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49811d0965ccb5dc74c79c021bc4b1ee
https://doi.org/10.1080/21541264.2017.1291395
https://doi.org/10.1080/21541264.2017.1291395
Autor:
Bernhard G. Herrmann, Anna D. Senft, Jinhua Liu, Frederic Koch, Phillip Grote, Matthias Marks, Lars Wittler, Anna Anurin, Smita Sudheer, Manuela Scholze, Karol Macura
Publikováno v:
Stem Cells. 34:1790-1800
Presomitic mesoderm (PSM) cells are the precursors of the somites, which flank both sides of the neural tube and give rise to the musculo-skeletal system shaping the vertebrate body. WNT and FGF signaling control the formation of both the PSM and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b496e96c06e1a19e449ff8885e9a36c
https://doi.org/10.1002/stem.2371
https://doi.org/10.1002/stem.2371
Autor:
Dennis Schifferl, Frederic Koch, Bernhard G. Herrmann, Smita Sudheer, Phillip Grote, Bernd Timmermann, Karol Macura, Lars Wittler, Manuela Scholze
Publikováno v:
Developmental Cell
The spinal cord and mesodermal tissues of the trunk such as the vertebral column and skeletal musculature derive from neuro-mesodermal progenitors (NMPs). Sox2, Brachyury (T), and Tbx6 have been correlated with NMP potency and lineage choice; however
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a98c06ddf37afeee8bc1d738a4b47e
https://hdl.handle.net/11858/00-001M-0000-002D-D639-B11858/00-001M-0000-002D-D637-F
https://hdl.handle.net/11858/00-001M-0000-002D-D639-B11858/00-001M-0000-002D-D637-F