Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Frederic J Hoerndli"'
Publikováno v:
eLife, Vol 13 (2024)
Our understanding of mitochondrial signaling in the nervous system has been limited by the technical challenge of analyzing mitochondrial function in vivo. In the transparent genetic model Caenorhabditis elegans, we were able to manipulate and measur
Externí odkaz:
https://doaj.org/article/fc1339337c274e029099f2ab6ad42094
Autor:
Rachel L. Doser, Frederic J. Hoerndli
Publikováno v:
Current Research in Neurobiology, Vol 2, Iss , Pp 100012- (2021)
Abstract:: Altered cognition and inefficient learning and memory are hallmarks of brain aging resulting from many small changes in the structure and function of neurons. One such change is a decrease in excitatory synaptic transmission mediated by gl
Externí odkaz:
https://doaj.org/article/157c91d21a5f47958754d909683ffa24
Publikováno v:
Lab Chip
Caenorhabditis elegans is an important genetic model for neuroscience studies, used for analyses of how genes control connectivity, neuronal function, and behavior. To date, however, most studies of neuronal function in C. elegans are incapable of ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3763b5f848cfca1fb370c981672d6cf9
https://europepmc.org/articles/PMC10091851/
https://europepmc.org/articles/PMC10091851/
Autor:
Rachel L, Doser, Frederic J, Hoerndli
Publikováno v:
microPublication biology. 2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54b44f3bafddb24bb12b4672285e8e72
https://pubmed.ncbi.nlm.nih.gov/35622512
https://pubmed.ncbi.nlm.nih.gov/35622512
Publikováno v:
J Neurosci
The AMPA subtype of synaptic glutamate receptors (AMPARs) plays an essential role in cognition. Their function, numbers, and change at synapses during synaptic plasticity are tightly regulated by neuronal activity. Although we know that long-distance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fae84ed0fa947027050edefe5e22f59
https://pubmed.ncbi.nlm.nih.gov/32847966
https://pubmed.ncbi.nlm.nih.gov/32847966
Publikováno v:
The European journal of neuroscience. 26(1)
Microarrays enable the observation of gene expression in experimental models of Alzheimer's disease (AD), with implications for the human pathology. Histopathologically, AD is characterized by Abeta-containing plaques and tau-containing neurofibrilla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcef8aa54dd5cd3c16d72846cd488c4b
https://pubmed.ncbi.nlm.nih.gov/17587323
https://pubmed.ncbi.nlm.nih.gov/17587323
Autor:
Frédéric J Hoerndli, Michael Walser, Erika Fröhli Hoier, Dominique de Quervain, Andreas Papassotiropoulos, Alex Hajnal
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4880 (2009)
BACKGROUND: Whole-genome association studies in humans have enabled the unbiased discovery of new genes associated with human memory performance. However, such studies do not allow for a functional or causal testing of newly identified candidate gene
Externí odkaz:
https://doaj.org/article/815f287dc46745609721cfd0cb41df2e
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/49d95d507a8d48b09671436fb6e5c625