Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Frederic Cadet"'
Autor:
Juan Carlos García-Cruz, Xareni Rebollar-Juarez, Aldo Limones-Martinez, Cristian Sadalis Santos-Lopez, Shotaro Toya, Toshinari Maeda, Corina Diana Ceapă, Lucia Blasco, María Tomás, Clara Estela Díaz-Velásquez, Felipe Vaca-Paniagua, Miguel Díaz-Guerrero, Daniel Cazares, Adrián Cazares, Melisa Hernández-Durán, Luis Esaú López-Jácome, Rafael Franco-Cendejas, Fohad Mabood Husain, Altaf Khan, Mohammed Arshad, Rosario Morales-Espinosa, Ana María Fernández-Presas, Frederic Cadet, Thomas K. Wood, Rodolfo García-Contreras
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2024)
BackgroundBacteriophage therapy is becoming part of mainstream Western medicine since antibiotics of clinical use tend to fail. It involves applying lytic bacteriophages that self-replicate and induce cell lysis, thus killing their hosts. Nevertheles
Externí odkaz:
https://doaj.org/article/b573c91b9e694dc28bd73b1af83bdd96
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/391f961d6fe144f5a11ecae42fd59881
Autor:
Anamya Ajjolli Nagaraja, Nicolas Fontaine, Mathieu Delsaut, Philippe Charton, Cedric Damour, Bernard Offmann, Brigitte Grondin-Perez, Frederic Cadet
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216178 (2019)
The selection of optimal enzyme concentration in multienzyme cascade reactions for the highest product yield in practice is very expensive and time-consuming process. The modelling of biological pathways is a difficult process because of the complexi
Externí odkaz:
https://doaj.org/article/1ae056acf01a482199ba859325303fbe
Autor:
Anamya Ajjolli Nagaraja, Philippe Charton, Xavier F. Cadet, Nicolas Fontaine, Mathieu Delsaut, Birgit Wiltschi, Alena Voit, Bernard Offmann, Cedric Damour, Brigitte Grondin-Perez, Frederic Cadet
Publikováno v:
Catalysts, Vol 10, Iss 3, p 291 (2020)
The metabolic engineering of pathways has been used extensively to produce molecules of interest on an industrial scale. Methods like gene regulation or substrate channeling helped to improve the desired product yield. Cell-free systems are used to o
Externí odkaz:
https://doaj.org/article/1938e960c43e4520a544d74759afa4b7
Publikováno v:
ACS Catalysis. 12:14243-14263
Autor:
Ophélie Lo-Thong-Viramoutou, Philippe Charton, Xavier F. Cadet, Brigitte Grondin-Perez, Emma Saavedra, Cédric Damour, Frédéric Cadet
Publikováno v:
Frontiers in Artificial Intelligence, Vol 5 (2022)
The use of machine learning (ML) in life sciences has gained wide interest over the past years, as it speeds up the development of high performing models. Important modeling tools in biology have proven their worth for pathway design, such as mechani
Externí odkaz:
https://doaj.org/article/5e2368f34bbc4da9a09e2e2edb1c0a96
Autor:
Akhila Melarkode Vattekatte, Julien Diharce, Joseph Rebehmed, Frédéric Cadet, Fabrice Gardebien, Catherine Etchebest, Alexandre G. de Brevern
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4511 (2023)
Conformational flexibility plays an essential role in antibodies’ functional and structural stability. They facilitate and determine the strength of antigen–antibody interactions. Camelidae express an interesting subtype of single-chain antibody,
Externí odkaz:
https://doaj.org/article/874e1da153014e579857add084302e21
Autor:
Ophélie Lo-Thong, Philippe Charton, Xavier F. Cadet, Brigitte Grondin-Perez, Emma Saavedra, Cédric Damour, Frédéric Cadet
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-19 (2020)
Abstract Metabolic pathway modeling plays an increasing role in drug design by allowing better understanding of the underlying regulation and controlling networks in the metabolism of living organisms. However, despite rapid progress in this area, pa
Externí odkaz:
https://doaj.org/article/3a136d7e4cb74fb8882a1b9f52cfe5f0
Autor:
Poonam Vishwakarma, Akhila Melarkode Vattekatte, Nicolas Shinada, Julien Diharce, Carla Martins, Frédéric Cadet, Fabrice Gardebien, Catherine Etchebest, Aravindan Arun Nadaradjane, Alexandre G. de Brevern
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3721 (2022)
VHH, i.e., VH domains of camelid single-chain antibodies, are very promising therapeutic agents due to their significant physicochemical advantages compared to classical mammalian antibodies. The number of experimentally solved VHH structures has sig
Externí odkaz:
https://doaj.org/article/94018e1a837c4ac6a55d0c9c1aed1383
Autor:
Akhila Melarkode Vattekatte, Nicolas Ken Shinada, Tarun J. Narwani, Floriane Noël, Olivier Bertrand, Jean-Philippe Meyniel, Alain Malpertuy, Jean-Christophe Gelly, Frédéric Cadet, Alexandre G. de Brevern
Publikováno v:
PeerJ, Vol 8, p e8408 (2020)
Antigen binding by antibodies requires precise orientation of the complementarity- determining region (CDR) loops in the variable domain to establish the correct contact surface. Members of the family Camelidae have a modified form of immunoglobulin
Externí odkaz:
https://doaj.org/article/12fc66473bc242b3baf0e78022ec6ed9