Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Frederic Bard"'
Akademický článek
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Autor:
Jeremy C Yeo, Felicia P Tay, Rebecca Bennion, Omar Loss, Jacquie Maignel, Laurent Pons, Keith Foster, Matthew Beard, Frederic Bard
Publikováno v:
eLife, Vol 12 (2024)
Botulinum neurotoxin A (BoNT/A) is a highly potent proteolytic toxin specific for neurons with numerous clinical and cosmetic uses. After uptake at the synapse, the protein is proposed to translocate from synaptic vesicles to the cytosol through a se
Externí odkaz:
https://doaj.org/article/fe90455008ae4419983b2985a8d0c38a
Autor:
Mona Nazemi, Bian Yanes, Montserrat Llanses Martinez, Heather J Walker, Khoa Pham, Mark O Collins, Frederic Bard, Elena Rainero
Publikováno v:
PLoS Biology, Vol 22, Iss 1, p e3002406 (2024)
Breast tumours are embedded in a collagen I-rich extracellular matrix (ECM) network, where nutrients are scarce due to limited blood flow and elevated tumour growth. Metabolic adaptation is required for cancer cells to endure these conditions. Here,
Externí odkaz:
https://doaj.org/article/73bd8338597b4be8864562ecae43c95e
Autor:
Shawn Jordan
Publikováno v:
The Journal of Cell Biology
Bard’s work focuses on how membrane trafficking regulates protein glycosylation and other cellular functions. At the age of seven, Frederic Bard’s father taught him about the atomic composition of water molecules. Bard was flabbergasted to learn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ab29a4baeebdbf848cad18a0853198
http://europepmc.org/articles/PMC4970336
http://europepmc.org/articles/PMC4970336
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Yew Chung Tang, Szu-Chi Ho, Elisabeth Tan, Alvin Wei Tian Ng, John R. McPherson, Germaine Yen Lin Goh, Bin Tean Teh, Frederic Bard, Steven G. Rozen
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-16 (2018)
Abstract Background Phosphatase and tensin homolog (PTEN) is one of the most frequently inactivated tumor suppressors in breast cancer. While PTEN itself is not considered a druggable target, PTEN synthetic-sick or synthetic-lethal (PTEN-SSL) genes a
Externí odkaz:
https://doaj.org/article/d5206bb396b84eb29668b60694b3e136
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214118 (2019)
The enzymes GALNTs add GalNAc sugar to Ser and Thr residues, forming the Tn glycan. GALNTs are activated by trafficking from Golgi to ER, a process driven by the Src kinase and negatively regulated by ERK8. This GALNTs activation (aka GALA) pathway i
Externí odkaz:
https://doaj.org/article/ec053ce163434cfc866fb2f9c383b961
Autor:
Kan Xing Wu, Patchara Phuektes, Pankaj Kumar, Germaine Yen Lin Goh, Dimitri Moreau, Vincent Tak Kwong Chow, Frederic Bard, Justin Jang Hann Chu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Enterovirus 71 (EV71) infection causes a spectrum of symptoms including neurological disease. To improve our understanding of EV71-host interactions, Wu et al. here perform a genome-wide RNAi screen, which implicates cell cycle regulation and ER-asso
Externí odkaz:
https://doaj.org/article/b570f2103dc44d409e3bad0d44e49be7
Autor:
David E Gordon, Joanne Chia, Kamburpola Jayawardena, Robin Antrobus, Frederic Bard, Andrew A Peden
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006698 (2017)
The cellular machinery required for the fusion of constitutive secretory vesicles with the plasma membrane in metazoans remains poorly defined. To address this problem we have developed a powerful, quantitative assay for measuring secretion and used
Externí odkaz:
https://doaj.org/article/92d90e1a7dd54c66888c6701d7f5eb15