X-rays minibeam radiation therapy at a conventional irradiator: Pilot evaluation in F98-glioma bearing rats and dose calculations in a human phantom

Autor: Marios Sotiropoulos, Elise Brisebard, Marine Le Dudal, Gregory Jouvion, Marjorie Juchaux, Delphine Crépin, Catherine Sebrie, Laurene Jourdain, Dalila Labiod, Charlotte Lamirault, Frederic Pouzoulet, Yolanda Prezado

Publikováno v: Clinical and Translational Radiation Oncology, Vol 27, Iss , Pp 44-49 (2021)

Minibeam radiation therapy (MBRT) is a type of spatial fractionated radiotherapy that uses submillimetric beams. This work reports on a pilot study on normal tissue response and the increase of the lifespan of glioma-bearing rats when irradiated with

Externí odkaz: https://doaj.org/article/d700386a48644ea3ae949d7d045ca7d1

Mapping the Future of Particle Radiobiology in Europe: The INSPIRE Project

Autor: Nicholas T. Henthorn, Olga Sokol, Marco Durante, Ludovic De Marzi, Frederic Pouzoulet, Justyna Miszczyk, Pawel Olko, Sytze Brandenburg, Marc Jan van Goethem, Lara Barazzuol, Makbule Tambas, Johannes A. Langendijk, Marie Davídková, Vladimír Vondráĉek, Elisabeth Bodenstein, Joerg Pawelke, Antony J. Lomax, Damien C. Weber, Alexandru Dasu, Bo Stenerlöw, Per R. Poulsen, Brita S. Sørensen, Cai Grau, Mateusz K. Sitarz, Anne-Catherine Heuskin, Stephane Lucas, John W. Warmenhoven, Michael J. Merchant, Ran I. Mackay, Karen J. Kirkby

Publikováno v: Frontiers in Physics, Vol 8 (2020)

Particle therapy is a growing cancer treatment modality worldwide. However, there still remains a number of unanswered questions considering differences in the biological response between particles and photons. These questions, and probing of biologi

Externí odkaz: https://doaj.org/article/88275246ca1f4bacb94b8d81b66f3077

Differential normal skin transcriptomic response in total body irradiated mice exposed to scattered versus scanned proton beams

Autor: Frederic Pouzoulet, Jean-Louis Habrand, François Sichel, Alexandre Leduc, Ludovic De Marzi, Carine Laurent, Erwan Corre, Frédérique Mégnin-Chanet, Dinu Stefan, Samia Chaouni

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.5876. ⟨10.1038/s41598-021-85394-0⟩

Proton therapy allows to avoid excess radiation dose on normal tissues. However, there are some limitations. Indeed, passive delivery of proton beams results in an increase in the lateral dose upstream of the tumor and active scanning leads to strong

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aafffdcc663f4291cfaf5c47d403aac
https://doaj.org/article/4a4f1e1463b84baf95bd357afe03d024

Publisher Correction: Differential normal skin transcriptomic response in total body irradiated mice exposed to scattered versus scanned proton beams

Autor: Erwan Corre, Jean-Louis Habrand, Samia Chaouni, Carine Laurent, Frederic Pouzoulet, Dinu Stefan, François Sichel, Alexandre Leduc, Ludovic De Marzi, Frédérique Mégnin-Chanet

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Scientific Reports

Proton therapy allows to avoid excess radiation dose on normal tissues. However, there are some limitations. Indeed, passive delivery of proton beams results in an increase in the lateral dose upstream of the tumor and active scanning leads to strong

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511c08f4b90e1b39c27d7b816dddeed6
https://doi.org/10.1038/s41598-021-97156-z

Primary CNS lymphoma patient-derived orthotopic xenograft model capture the biological and molecular characteristics of the disease

Autor: Justine Guegan, Emmanuelle Menet, Mailys Daniau, Louis Royer-Perron, Frederic Davi, Matthieu Peyre, Khê Hoang-Xuan, Frederic Pouzoulet, Karima Mokhtari, Anne Schnitzler, Franck Assayag, Carole Soussain, Agusti Alentorn, Magali Le Garff-Tavernier, Dalila Labiod

Publikováno v: Blood Cells, Molecules, and Diseases. 75:1-10

Primary CNS lymphomas (PCNSL) are rare and poor prognosis diffuse large B-cell lymphomas. Because of the brain tumor environment and the restricted distribution of drugs in the CNS, specific PCNSL patient-derived orthotopic xenograft (PDOX) models ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f7e12ca8a36ffd5db247c1d864dd27
https://doi.org/10.1016/j.bcmd.2018.11.005