Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Freddy A. Bernal"'
Autor:
François Keiff, Freddy A. Bernal, Melanie Joch, Thibault J. W. Jacques dit Lapierre, Yan Li, Phil Liebing, Hans-Martin Dahse, Ivan Vilotijevic, Florian Kloss
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-8 (2024)
Abstract Tuberculosis, caused by Mycobacterium tuberculosis, remains a major public health concern, demanding new antibiotics with innovative therapeutic principles due to the emergence of resistant strains. Benzothiazinones (BTZs) have been develope
Externí odkaz:
https://doaj.org/article/b67cd7e422c1424b8c78cd29cda51297
Autor:
Freddy A. Bernal, Thomas J. Schmidt
Publikováno v:
Molecules, Vol 28, Iss 8, p 3399 (2023)
Leishmaniasis, a parasitic disease that represents a threat to the life of millions of people around the globe, is currently lacking effective treatments. We have previously reported on the antileishmanial activity of a series of synthetic 2-phenyl-2
Externí odkaz:
https://doaj.org/article/8995d39fa5174e348323835e353cf9b4
Autor:
Freddy A. Bernal, Ericsson Coy-Barrera
Publikováno v:
Molecules, Vol 27, Iss 9, p 2832 (2022)
Lupinus plants are well-recognized due to their significant alkaloid content, which has made them the subject of several studies. However, the lack of chemical and biological information on the Colombian Lupinus species remains a fact. Therefore, the
Externí odkaz:
https://doaj.org/article/6c4bf6136053406ea433b90b03faa77a
Publikováno v:
Molecules, Vol 26, Iss 17, p 5249 (2021)
On the basis of the finding that various aminoalkyl-substituted chromene and chromane derivatives possess strong and highly selective in vitro bioactivity against Plasmodium falciparum, the pathogen responsible for tropical malaria, we performed a st
Externí odkaz:
https://doaj.org/article/77b165c5294a41bba2b3acac28f1a01f
Publikováno v:
Molecules, Vol 25, Iss 23, p 5704 (2020)
Leishmaniasis is a parasitic morbid/fatal disease caused by Leishmania protozoa. Twelve million people worldwide are appraised to be currently infected, including ca. two million infections each year, and 350 million people in 88 countries are at ris
Externí odkaz:
https://doaj.org/article/50b879044822402a919e16da2d7b8023
Publikováno v:
Química Nova, Vol 39, Iss 2, Pp 160-166 (2016)
The calyxes of Hibiscus sabdariffa are used in traditional medicine around the world. However, quality assurance protocols and chemical variability have not been previously analyzed. In the present study, chemical characterization of a set of samples
Externí odkaz:
https://doaj.org/article/d6dc662f73a24a7f894b023c5e84420a
Autor:
Freddy A. Bernal, Ericsson Coy-Barrera
Publikováno v:
Molecules, Vol 20, Iss 7, Pp 13165-13204 (2015)
Xanthones are secondary metabolites which have drawn considerable interest over the last decades due to their antimicrobial properties, among others. A great number of this kind of compounds has been therefore reported, but there is a limited amount
Externí odkaz:
https://doaj.org/article/8e51188c5b134c4a87c160a89e26650f
Autor:
Freddy A. Bernal, Ericsson Coy-Barrera
Publikováno v:
Molecules, Vol 19, Iss 5, Pp 5550-5569 (2014)
A great number of sesquiterpenes are reported in the available literature as good antileishmanial leads. However, their mode of action at the molecular level has not been elucidated. The lack of molecular studies could be considered an impediment for
Externí odkaz:
https://doaj.org/article/2f9591929a734bbab88858d8a0ad4655
Publikováno v:
Chemistry & Biodiversity. 19
Magnolia grandiflora is an aromatic plant widely distributed around the world. In Colombia, and more specifically in Bogotá, M. grandiflora has been introduced as part of urban forestry programs, and their specimens are therefore subjected to severa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d72a90d6d7c8b6c59a19bea16ed1d7
https://doi.org/10.1002/cbdv.202200448
https://doi.org/10.1002/cbdv.202200448
Autor:
Sebastian Schieferdecker, Freddy A. Bernal, K. Philip Wojtas, François Keiff, Yan Li, Hans-Martin Dahse, Florian Kloss
Publikováno v:
Journal of medicinal chemistry. 65(9)
Nitrobenzothiazinones (BTZs) are a very potent class of antibiotics against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4970dbab551bd9d71b92203608fff72b
https://pubmed.ncbi.nlm.nih.gov/35502994
https://pubmed.ncbi.nlm.nih.gov/35502994