Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Freddie Salsbury"'
Publikováno v:
Journal of Nucleic Acids, Vol 2011 (2011)
Topoisomerase 1 (Top1) enzymes regulate DNA superhelicity by forming covalent cleavage complexes that undergo controlled rotation. Substitution of nucleoside analogs at the +1 position of the DNA duplex relative to the Top1 cleavage site inhibits DNA
Externí odkaz:
https://doaj.org/article/750e52c6bb934f349072ab7d61525691
Autor:
Aksana Vasilyeva, Jill E. Clodfelter, Michael J. Gorczynski, Anthony R. Gerardi, S. Bruce King, Freddie Salsbury, Karin D. Scarpinato
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
Mismatch repair proteins modulate the cytotoxicity of several chemotherapeutic agents. We have recently proposed a “death conformation” of the MutS homologous proteins that is distinguishable from their “repair conformation.” This conformatio
Externí odkaz:
https://doaj.org/article/9dcf76a2d46946c4ba5aba5171c200da
Autor:
shimaa naguib, Omar Aly, Gamal Abourhma, Stephen King, Freddie Salsbury, Karin Scarpinato, Andrew Diamanduros
Publikováno v:
Octahedron Drug Research. 2:21-35
Autor:
Alia Ghoneum, Daniela Gonzalez, Hesham Afify, Junjun Shu, Abigail Hegarty, Jemima Adisa, Michael Kelly, Samuel Lentz, Freddie Salsbury, Neveen Said
Publikováno v:
Cancers; Volume 14; Issue 20; Pages: 5099
Epithelial Ovarian cancer (OvCa) is the leading cause of death from gynecologic malignancies in the United States, with most patients diagnosed at late stages. High-grade serous cancer (HGSC) is the most common and lethal subtype. Despite aggressive
Publikováno v:
Journal of Molecular Modeling; Feb2009, Vol. 15 Issue 2, p133-145, 13p