Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Fred Y Shen"'
Autor:
Hrishikesh M Rao, Juan eSan Juan, Fred Y Shen, Jennifer E Villa, Kimia S Rafie, Marc A Sommer
Publikováno v:
Frontiers in Computational Neuroscience, Vol 10 (2016)
As we look around a scene, we perceive it as continuous and stable even though each saccadic eye movement changes the visual input to the retinas. How the brain achieves this perceptual stabilization is unknown, but a major hypothesis is that it reli
Externí odkaz:
https://doaj.org/article/f7afd4d3c3bf4c3bb49a1dedfce18308
Autor:
Fred Y. Shen, Margaret M. Harrington, Logan A. Walker, Hon Pong Jimmy Cheng, Edward S. Boyden, Dawen Cai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Mapping neuroanatomy is a foundational goal of connectomics, and the gold standard method is electron microscopy as light microscopy lacks nanoscale resolution. Here the authors develop a strategy using multicolor genetic labeling (Brainbow) and expa
Externí odkaz:
https://doaj.org/article/0eb3bbd03f284394bd5506dd6b183bad
Autor:
Lorraine R Horwitz, Hankyu Lee, Chia Chun Hor, Fred Y Shen, Wei Cai, Chen Li, Emily Ling-Lin Pai, Tin Long Rex Fung, Ilma Rovcanin, Kevin P Pipe, X.Z. Shawn Xu, Dawen Cai, Bo Duan
SUMMARYTemperature information is precisely processed in the nervous system. While progress has been made in identifying molecular thermosensors in the periphery, the neural circuits that process temperature information in the central nervous system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f1f4eb317a21af2eb918babacd9e14a
https://doi.org/10.1101/2022.03.23.485555
https://doi.org/10.1101/2022.03.23.485555
Autor:
Margaret M. Harrington, Dawen Cai, Edward S. Boyden, Logan A. Walker, Hon Pong Jimmy Cheng, Fred Y. Shen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Mapping neuroanatomy is a foundational goal towards understanding brain function. Electron microscopy (EM) has been the gold standard for connectivity analysis because nanoscale resolution is necessary to unambiguously resolve synapses. However, mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c955f999df50e1774fdf4d2a06f0a49f
https://doaj.org/article/0eb3bbd03f284394bd5506dd6b183bad
https://doaj.org/article/0eb3bbd03f284394bd5506dd6b183bad
Publikováno v:
ISBI
Reconstructing neuron morphology is central to uncovering the complexity of the nervous system. That is because the morphology of a neuron essentially provides the physical constraints to its intrinsic electrophysiological properties and its connecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7138f20aedbbe742ce6a126f6e84d9d
https://doi.org/10.1109/isbi48211.2021.9433932
https://doi.org/10.1109/isbi48211.2021.9433932
Autor:
Fred Y. Shen, Dawen Cai, Ye Li, Logan A. Walker, Nigel S. Michki, Kayvon Sanjasaz, Yimeng Zhao, Cheng Yu Lee
SUMMARYTheDrosophilatype-II neuroblast (NB) lineages present an attractive model to investigate the neural differentiation process. With only 16 stem cells, the type-II NB lineages generate many intermediate neural progenitors (INPs) to rapidly expan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dae0f7de8937a046885ac401e70f03c2
https://doi.org/10.1101/2020.07.02.184549
https://doi.org/10.1101/2020.07.02.184549
Autor:
Wenjia Cao, Yimeng Zhao, Cheng Yu Lee, Kayvon Sanjasaz, Ye Li, Fred Y. Shen, Nigel S. Michki, Dawen Cai, Logan A. Walker
Publikováno v:
Cell reports
SUMMARY The Drosophila type II neuroblast lineages present an attractive model to investigate the neurogenesis and differentiation process as they adapt to a process similar to that in the human outer subventricular zone. We perform targeted single-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3142b970e0d1c323b7ced518ac95555
https://doi.org/10.1016/j.celrep.2021.109039
https://doi.org/10.1016/j.celrep.2021.109039
Autor:
John M Webb, Tingxin Xiao, Yan Yan, Madeleine Vandenbrink, Lia Y Min, Benjamin V Sadis, Fred Y. Shen, Johanna S Stecher, Aslan S. Dizaji, Robert S Huth, Takao K. Hensch, Jeff W. Lichtman, Luke J Bogart, Erik D. Herzog, Douglas H. Roossien, Sriakhila Akula, Dawen Cai, Cristina Mazuski, Ye Li
Publikováno v:
Bioinformatics
Summary This note describes nTracer, an ImageJ plug-in for user-guided, semi-automated tracing of multispectral fluorescent tissue samples. This approach allows for rapid and accurate reconstruction of whole cell morphology of large neuronal populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c04600e12050efc6f1dbb206eff3aa
https://pubmed.ncbi.nlm.nih.gov/30715234
https://pubmed.ncbi.nlm.nih.gov/30715234
Autor:
Pimonrat Ketsawatsomkron, Mei Ling A. Joiner, Daniel W. Nuno, Olha M. Koval, Isabella M. Grumbach, Mark E. Anderson, William Kutschke, Fred Y. Shen, Weiwei Li, Curt D. Sigmund, Anand M. Prasad, Hui Li, Kathryn G. Lamping, Robert M. Weiss
Publikováno v:
Hypertension. 62:434-441
The multifunctional Ca 2+ /calmodulin-dependent kinase II (CaMKII) is activated by vasoconstrictors in vascular smooth muscle cells (VSMC), but its impact on vasoconstriction remains unknown. We hypothesized that CaMKII inhibition in VSMC decreases v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87d3d6b768ea24486715c52a6cb9f23
https://doi.org/10.1161/hypertensionaha.113.01508
https://doi.org/10.1161/hypertensionaha.113.01508
Autor:
Fred Y. Shen, Jeffrey M. Kidd
QuicK-mer is a unified pipeline for estimating genome copy-number from high-throughput Illumina sequencing data. QuicK-mer utilizes the Jellyfish application to efficiently tabulate counts of predefined sets of k-mers. The program performs GC-normali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b27a86b1b2a372eb6a7e77f3d193b8c
https://doi.org/10.1101/028225
https://doi.org/10.1101/028225